NK2 Homeobox 6 Protéines (NKX2-6)

NKX2-6 encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. De plus, nous expédions NK2 Homeobox 6 Anticorps (50) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
NKX2-6 137814 A6NCS4
NKX2-6 18092 P43688
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Top NK2 Homeobox 6 Protéines sur anticorps-enligne.fr

Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,749.58
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,749.58
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails

NKX2-6 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour NK2 Homeobox 6 (NKX2-6) partenaires d'interaction

Xenopus laevis NK2 Homeobox 6 (NKX2-6) interaction partners

  1. Results suggest that XNkx2-10, like XNkx2-3 and XNkx2-5, is necessary for normal Xenopus heart development.

Human NK2 Homeobox 6 (NKX2-6) interaction partners

  1. This study firstly links NKX2.6 loss-of-function mutation with increased susceptibility to isolated VSD.

  2. Data associated genetically defective NK2 homeobox 6 (NKX2-6) with enhanced susceptibility to atrial fibrillation (AF).

  3. Heterozygous mutations in Nkx2.6, p.V176M and p.K177X, were identified in 2 unrelated patients, one with tetralogy of Fallot and one with double outlet of right ventricle and ventricular septal defect. Increased vulnerability to TOF or DORV is discussed.

  4. NKX2-6 plays a role in human cardiogenesis.

  5. weakly activates transcription of a Cx40 promoter, may have role in heart development

  6. NKX2.5/NKX2.6 mutations are not a common cause of isolated type 1 truncus arteriosus in a small cohort of multiethnic cases.

Profil protéine NK2 Homeobox 6 (NKX2-6)

Profil protéine

This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.

Gene names and symbols associated with NK2 Homeobox 6 Protéines (NKX2-6)

  • NK2 homeobox 6 L homeolog (nkx2-6.L)
  • NK2 homeobox 6 (NKX2-6)
  • NK2 homeobox 6 (nkx2-6)
  • NK2 homeobox 6 (Nkx2-6)
  • AV044928 Protéine
  • CSX2 Protéine
  • Nkx-2.6 Protéine
  • nkx2-10-A Protéine
  • Nkx2.6 Protéine
  • NKX2.8 Protéine
  • NKX2F Protéine
  • NKX4-2 Protéine
  • tinman Protéine
  • Tix Protéine
  • Xnkx2-10 Protéine

Protein level used designations for NK2 Homeobox 6 Protéines (NKX2-6)

NK2 transcription factor related, locus 6 , homeodomain protein XNkx2-10 , homeobox protein Nkx-2.6 , homeobox protein Nkx-2.8 , NK2 transcription factor related, locus 6 (Drosophila) , homeobox protein NK2 homolog F , homeobox protein NKX2.6 , tinman paralog , Drosophila NK2 transcription factor related, locus 6 , homeobox protein NK-2 homolog F

GENE ID SPECIES
373736 Xenopus laevis
396037 Gallus gallus
464060 Pan troglodytes
486113 Canis lupus familiaris
100038094 Xenopus (Silurana) tropicalis
137814 Homo sapiens
18092 Mus musculus
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