NSFL1 (p97) Cofactor (p47) Protéines (NSFL1C)

N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. De plus, nous expédions NSFL1C Anticorps (26) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
NSFL1C 55968 Q9UNZ2
NSFL1C 386649 Q9CZ44
NSFL1C 83809 O35987
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Top NSFL1C Protéines sur anticorps-enligne.fr

Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails
Levure Rat His tag   1 mg 60 to 71 Days
$3,014.00
Détails
Levure Boeuf (Vache) His tag   1 mg 60 to 71 Days
$3,014.00
Détails

NSFL1C Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour NSFL1 (p97) Cofactor (p47) (NSFL1C) partenaires d'interaction

Human NSFL1 (p97) Cofactor (p47) (NSFL1C) interaction partners

  1. p47 promotes, whereas SASK1 delays the degradation of a single ERAD substrate, alpha-TCR. Additionally, we found that SAKS1 selectively inhibits the degradation of ERAD substrates without affecting cytosolic proteasomal substrates.

  2. The present results for the first time demonstrate that BDNF induces NADPH oxidase -derived reactive oxygen species generation through activation of p47 phox in a TrkB receptor-dependent manner

  3. human p37/p47 and their C. elegans orthologue UBXN-2 regulate centrosome function in prophase by limiting the recruitment of Aurora A

  4. The binding of p47 to polyubiquitinated NEMO triggers the lysosomal degradation of NEMO, thereby inhibiting IKK activation.

  5. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.

Mouse (Murine) NSFL1 (p97) Cofactor (p47) (NSFL1C) interaction partners

  1. our data identify EBP50 as a previously unidentified regulator of Nox1 and support that it promotes Nox1 activity by binding p47(phox) This interaction is pivotal for agonist-induced smooth muscle ROS, hypertrophy, and vasoconstriction and has implications for ROS-mediated physiological and pathophysiological processes.

  2. Data suggest that NADPH oxidase-derived cytosolic superoxide is increased in islets upon oleate exposure and leads to beta cell dysfunction; whole-body NADPH oxidase inhibition (via p47 knockout) decreases superoxide and restores islet function.

  3. that p47 ubiquitin regulatory X domain domains may act as general p97/valosin containing protein/CDC48 binding modules and that adaptor binding for N-ethylmaleimide sensitive factor and p97 might involve different binding sites

  4. genetic ablation of components of NADPH oxidase enhances susceptibility to the proinflammatory effects of CS leading to airspace enlargement and alveolar damage.

Profil protéine NSFL1C

Profil protéine

N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.

Gene names and symbols associated with NSFL1C

  • NSFL1 cofactor (NSFL1C)
  • NSFL1 (p97) cofactor (p47) (nsfl1c)
  • NSFL1 (p97) cofactor (p47) (Nsfl1c)
  • NSFL1 cofactor (Nsfl1c)
  • dJ776F14.1 Protéine
  • hm:zehn2383 Protéine
  • Munc-18c Protéine
  • p47 Protéine
  • Stxbp3a Protéine
  • UBX1 Protéine
  • UBXD10 Protéine
  • UBXN2C Protéine
  • wu:fc88f08 Protéine
  • XY40 Protéine
  • zehn2383 Protéine
  • zgc:101636 Protéine

Protein level used designations for NSFL1C

p47 protein , NSFL1 cofactor p47 , NSFL1 (p97) cofactor (p47) , p97 cofactor p47 , NSFL1 cofactor p47-like , SHP1 homolog , UBX domain-containing protein 2C , XY body-associated protein XY40

GENE ID SPECIES
469859 Pan troglodytes
492805 Danio rerio
715743 Macaca mulatta
100013261 Monodelphis domestica
100172420 Pongo abelii
100340741 Oryctolagus cuniculus
100398828 Callithrix jacchus
55968 Homo sapiens
386649 Mus musculus
83809 Rattus norvegicus
526612 Bos taurus
419268 Gallus gallus
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