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The protein encoded by NPPC is proteolytically processed to form a secreted hormone of the natriuretic peptide family. De plus, nous expédions Natriuretic Peptide Precursor C Anticorps (17) et beaucoup plus de produits pour cette protéine.
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C-type natriuretic peptide (CNP)administration significantly decreased the secretion and expression of MMP-2 (Montrer MMP2 Kits ELISA) and MMP-9 (Montrer MMP9 Kits ELISA) in the cultured mesangial cells ; (2) the secretion and expression of TIMP-1 (Montrer TIMP1 Kits ELISA) progressively elevated after treatment with CNP (Montrer CNP Kits ELISA) for 24 and 48 h, whereas declined at later time point; (3) CNP (Montrer CNP Kits ELISA) expression was negatively correlated with MMP-2 (Montrer MMP2 Kits ELISA) and MMP-9 (Montrer MMP9 Kits ELISA) expression.
CNP (Montrer CNP Kits ELISA) level in pericardial fluid is a more sensitive marker of LV dysfunction than CNP (Montrer CNP Kits ELISA) levels in plasma in coronary artery disease patients undergoing coronary artery bypass grafting.
Data suggest mutations in NPR2 in patients with skeletal overgrowth alter conformation: A488P/R655C missense mutations yield conformation mimicking allosterically activated NPR2; A488P mutation sets phosphorylation as requirement for CNP (Montrer CNP Kits ELISA)-dependent activation; R655C mutation abrogates need for phosphorylation; ATP analog inhibits mutants. (NPR2 = atrial natriuretic factor (Montrer NPPA Kits ELISA) receptor B; CNP (Montrer CNP Kits ELISA) = C-type natriuretic peptide)
CNP (Montrer CNP Kits ELISA) may play a more important role than BNP and ANP (Montrer NPPA Kits ELISA) related peptides, as risk marker of obesity
CNP (Montrer CNP Kits ELISA) and FGF-23 (Montrer FGF23 Kits ELISA) act through a close or reciprocal pathway and are in agreement with recent studies demonstrating a down-regulatory role of the mitogen-activated protein kinase (Montrer MAPK1 Kits ELISA) activity by CNP (Montrer CNP Kits ELISA)
CNP (Montrer CNP Kits ELISA)/NPR-B (Montrer NPR2 Kits ELISA) can affect sperm motility and acrosome reaction, thus regulating the reproductive function of males
CNP (Montrer CNP Kits ELISA) levels rose after paroxysmal supraventricular tachycardia and continued to rise after the termination.
examined whether CNP reduces hyaluronan production and export via members of the multidrug resistance protein (MRP) and diminishes pro-inflammatory effects in chondrocytes
Plasma CNP (Montrer CNP Kits ELISA) might serve as a useful predictor for the therapeutic efficacy of metoprolol on postural tachycardia syndrome in children.
CNP (Montrer CNP Kits ELISA)/proCNP could be new markers in human prostate cancer
CNP and BNP serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals.
The first intron in the CNP sequence does not contain any additional enhancer-binding sites. However, the signal sequence is indispensable for secretion of CNP and its appropriate physiological function.
Inhibition of restenosis without compromising reendothelialization makes use of gene transfer into endothelial cells and muscle, smooth, vascular cells by administration of CNP.
Regional differences in BNP and CNP expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.
Data suggest natriuretic peptide precursor C (NPPC) can regulate oogenesis/gap junction mediated communication between oocytes and cumulus cells; here, NPPC is used in non-pharmacological coordination of meiotic prophase in vitro oocyte maturation.
E2-ERs system was functional in maintaining oocyte meiotic arrest by regulating the expression of natriuretic peptide C and natriuretic peptide receptor 2 (NPPC/NPR2)
CNP (Montrer CNP Kits ELISA) activates bone turnover and remodeling in vivo and possibly accelerates fracture healing in a mouse model.
The up-to-day world-wide data about the structure, distribution, and physiological effects of the most poorly known among the natriuretic peptides--the C-type (CNP (Montrer CNP Kits ELISA))--are summarized in the review.
Connexin mimetics directed against connexin-43 (Cx43 (Montrer GJA1 Kits ELISA) CMP (Montrer MATN1 Kits ELISA)) overcame NPPC-mediated meiotic arrest in both isolated cumulus oocyte complexes and antral follicles.
CNP (Montrer CNP Kits ELISA)/NPR-C (Montrer NPR3 Kits ELISA) pathway has potential as a disease-modifying therapeutic target for cardiovascular disorders
Data indicate an important, previously neglected, role of NEP (Montrer MME Kits ELISA) for regulation of luminal factors in the epididymis and suggest a novel role for CNP (Montrer CNP Kits ELISA)/guanylyl cyclase B in the epididymal epithelium
CNP (Montrer CNP Kits ELISA) overexpression in chondrocytes can prevent endochondral growth delay and protect against cartilage damage in a mouse model of inflammatory arthritis.
Data suggest that intracerebroventricular administration of C-type natriuretic peptide (CNP-22 or CNP (Montrer CNP Kits ELISA)-53) has anorexigenic effect on hypothalamic neurons via activation of melanocortin/melanocortin receptor signal transduction.
CNP (Montrer CNP Kits ELISA)/NPR2 signaling is essential for oocyte meiotic arrest in early antral follicles and activated LH/amphiregulin (Montrer AREG Kits ELISA)/EGFR (Montrer EGFR Kits ELISA) signaling pathway suppresses this signal by downregulating Nppc expression.
we show that CNP (Montrer CNP Kits ELISA) plays important region-specific roles in the GI tract of mice.
The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic.
C-type natriuretic peptide
, natriuretic peptide precursor C
, natriuretic peptide precursor type C
, C-type natriuretic peptide 3