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Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.. De plus, nous expédions Natural Cytotoxicity Triggering Receptor 2 Protéines (8) et Natural Cytotoxicity Triggering Receptor 2 Kits (4) et beaucoup plus de produits pour cette protéine.
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Human Monoclonal NCR2 Primary Antibody pour Agon, CyTOF - ABIN5012967
Shi, Tricot, Garg, Malaviarachchi, Szmania, Kellum, Storrie, Mulder, Shaughnessy, Barlogie, van Rhee: Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. dans Blood 2008
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Human Monoclonal NCR2 Primary Antibody pour FACS - ABIN2480069
Fuchs, Cella, Kondo, Colonna: Paradoxic inhibition of human natural interferon-producing cells by the activating receptor NKp44. dans Blood 2005
Human Monoclonal NCR2 Primary Antibody pour FACS - ABIN4896419
Longman, Diehl, Victorio, Huh, Galan, Miraldi, Swaminath, Bonneau, Scherl, Littman: CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. dans The Journal of experimental medicine 2014
Study identified a novel ligand for NKp44 on astrocytes. Expression of this novel ligand decreased with increasing HIV-3S peptide concentration and blocking this novel ligand decreased NK cell killing. NK cell killing of astrocytes was decreased when astrocytes were incubated with HIV-3S peptide. NKp44 has a protective effect on astrocytes from NK cell mediated killing during HIV infection and impact astrocyte's role.
NKp44 and NKp30 (Montrer NCR3 Anticorps) splice variants profiles are tissue/condition specific and demonstrate similarity between placenta and cancerous tissues.
NKp44-1 expression was significantly associated with poor survival of AML (Montrer RUNX1 Anticorps) patients. Moreover, activation of PBMC from healthy controls showed co-dominant expression of NKp44-1 and NKp44-3, while primary NK clones show more diverse NKp44 splice variant profiles.
On CD56 (Montrer NCAM1 Anticorps)(+) CD3 (Montrer CD3 Anticorps)(-) cells, NKp44 and NKp46 (Montrer NCR1 Anticorps) expressions were high in the acute hepatitis E patients, whereas NKp30 (Montrer NCR3 Anticorps), NKp44, NKp46 (Montrer NCR1 Anticorps) and NKG2D (Montrer KLRK1 Anticorps) were high in the recovered individuals.
demonstrated that the mitogen and iK562 exposure to peripheral blood mononuclear cells can significantly improve NK activity which is co-related to the higher expression of NKp44 and NKG2D (Montrer KLRK1 Anticorps)
NCR(+) ILC3 from skin and blood of psoriasis patients produced IL-22 (Montrer IL22 Anticorps), which is regarded as a key driver of epidermal thickening, suggesting that NCR(+) ILC3 may participate in psoriasis pathology.
Balance between activating NKG2D (Montrer KLRK1 Anticorps), DNAM-1 (Montrer CD226 Anticorps), NKp44 and NKp46 (Montrer NCR1 Anticorps) and inhibitory CD94 (Montrer KLRD1 Anticorps)/NKG2A (Montrer KLRC1 Anticorps) receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
NKp44+ ILC3 are expressed in human skin and blood and may have a role in psoriasis pathogenesis
Expression of NKp44 ligand by normal articular chondrocytes is not involved in their killing by unstimulated NK cells; however, it is responsible for anti-chondrocyte cytotoxicity mediated by long-term activated NK cells.
MLL5 (Montrer MLL5 Anticorps) is a cellular ligand for the natural cytotoxicity receptor NKp44.
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
natural cytotoxicity triggering receptor 2
, NK cell activating receptor (NKp44)
, NK cell-activating receptor
, lymphocyte antigen 95 (activating NK-receptor; NK-p44)
, lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44)
, natural killer cell p44-related protein