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NPSR1 is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. De plus, nous expédions NPSR1 Anticorps (62) et NPSR1 Kits (12) et beaucoup plus de produits pour cette protéine.
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Findings demonstrate that neuropeptide S (Montrer NPS Protéines), via selective activation of the neurons bearing neuropeptide S receptor in the subiculum complex, ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 in mice.
Study demonstrated that NPS (Montrer NPS Protéines) produces anti-aggressive effects in mice through the selective activation of NPSR and that the endogenous NPS (Montrer NPS Protéines)/NPSR system can exert a role in the control of aggressiveness levels under the present experimental conditions
the deletion of NPSR did not lead to compensatory changes in the vigilance-promoting effects of the CRF (Montrer CRH Protéines) and Hcrt (Montrer OX Protéines)-1/Ox-A systems.
A single nucleotide polymorphism in Npsr1 that increases its activity is linked to higher anxiety.
In conclusion, the present study indicates that the NPS (Montrer NPS Protéines)/NPSR system does not tonically control locomotion, sensitivity to diazepam, anxiety, depressive-like behaviours, memory and pain transmission in mice.
These results support an important role of neuropeptide S (Montrer NPS Protéines) in regulating locomotor activity.
NPSR1 is essential in mediating NPS (Montrer NPS Protéines) effects on behavior.
GPRA may contribute to the asthmatic phenotype by altering the activity of other pathways, such as neurally mediated mechanisms, that contribute to disease
The isolation and characterization of an arginine vasotocin receptor in mice is reported.
Results show higher fronto-limbic connectivity in adolescent A allele carriers vs. children carrying the A allele, a pattern which could not be discerned in TT homozygotes. Adolescent NPSR1 TT risk genotype carriers vs. adolescent A allele carriers displayed a reduced fronto-amygdala and fronto-insula effective connectivity suggesting basis of risk-increasing effect of the NPSR1T allele for anxiety.
Sequence variation in NPSR1 may contribute to sex differences in stress regulation.
we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5 (Montrer CCL5 Protéines), HPGDS (Montrer HPGDS Protéines), and NPSR1) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS (Montrer HPGDS Protéines) and NPSR1 in plasma.
The interaction between 5-HTT (Montrer SLC6A4 Protéines) (LL) and BDNF (A (Montrer BDNF Protéines)+) increased the risk of anxiety, and the interaction between BDNF (A (Montrer BDNF Protéines)+, GG) and NPSR1 (AA, T+) increased the risk of depression in asthmatic patients.
findings demonstrate that hNPS-(1-10) is a biased agonist favoring Galphaq (Montrer GNAQ Protéines)-dependent signaling. It may represent a valuable chemical probe for further investigation of the therapeutic potential of human NPS (Montrer NPS Protéines) receptor-directed signalingin vivo.
anxiety sensitivity correlated negatively with prefrontal activity in NPSR1 rs324981 carriers possibly suggesting a decompensation of the adaptive compensatory upregulation
Results suggest the functional NPSR1 gene A/T variant to influence glutamate (Montrer GRIN1 Protéines)+glutamine (Montrer GFPT1 Protéines) concentrations in the bilateral anterior cingulate cortex in healthy male subjects during CCK-4 (Montrer PTK7 Protéines) induced panic
The T-allele of the NPSR1 rs324981 polymorphism is associated with increased impulsivity and ADHD-related traits in non-clinical cohorts.
The results suggest neuropeptide S receptor gene variation to be associated with alterations of prefrontal functioning in the attentional functions alerting and executive control partly modulated by anxiety sensitivity.
Results show that NPSR1 polymorphism is associated with AUD and alcohol consumption, dependent on sex, environment and age.
GPRA variants are not an important contributor to childhood asthma and atopy susceptibility in a Mexican population.
This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.
G protein-coupled receptor 154
, G protein-coupled receptor PGR14
, G-protein coupled receptor 154
, G-protein coupled receptor PGR14
, neuropeptide S receptor
, vasotocin receptor
, G protein-coupled receptor for asthma susceptibility
, G-protein coupled receptor for asthma susceptibility
, vasopressin receptor-related receptor 1