Neuropeptide S Receptor 1 Protéines (NPSR1)

NPSR1 is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. De plus, nous expédions NPSR1 Anticorps (63) et NPSR1 Kits (12) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
NPSR1 319239 Q8BZP8
Rat NPSR1 NPSR1 300458  
NPSR1 387129 Q6W5P4
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,262.31
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,493.38
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Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Humain Inconjugué   100 μg Connectez-vous pour afficher 11 to 18 Days
$582.75
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NPSR1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human , ,
,

Plus protéines pour Neuropeptide S Receptor 1 (NPSR1) partenaires d'interaction

Mouse (Murine) Neuropeptide S Receptor 1 (NPSR1) interaction partners

  1. Findings demonstrate that neuropeptide S, via selective activation of the neurons bearing neuropeptide S receptor in the subiculum complex, ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 in mice.

  2. Study demonstrated that NPS produces anti-aggressive effects in mice through the selective activation of NPSR and that the endogenous NPS/NPSR system can exert a role in the control of aggressiveness levels under the present experimental conditions

  3. the deletion of NPSR did not lead to compensatory changes in the vigilance-promoting effects of the CRF and Hcrt-1/Ox-A systems.

  4. A single nucleotide polymorphism in Npsr1 that increases its activity is linked to higher anxiety.

  5. In conclusion, the present study indicates that the NPS/NPSR system does not tonically control locomotion, sensitivity to diazepam, anxiety, depressive-like behaviours, memory and pain transmission in mice.

  6. These results support an important role of neuropeptide S in regulating locomotor activity.

  7. NPSR1 is essential in mediating NPS effects on behavior.

  8. GPRA may contribute to the asthmatic phenotype by altering the activity of other pathways, such as neurally mediated mechanisms, that contribute to disease

  9. The isolation and characterization of an arginine vasotocin receptor in mice is reported.

Human Neuropeptide S Receptor 1 (NPSR1) interaction partners

  1. A decreased risk of psychological stress was only found in TT of NPSR1 (rs324981): A allele carriers vs. TT genotype (OR 1.64, 95% CI 1.11, 2.42), and AT genotype vs. TT genotype (OR 1.76, 95% CI 1.17, 2.65). We found that the NPSR1 (rs324981) T/T genotype decreased the risk of psychological stress, while the overall coping style was a risk factor for psychological stress.

  2. Results show higher fronto-limbic connectivity in adolescent A allele carriers vs. children carrying the A allele, a pattern which could not be discerned in TT homozygotes. Adolescent NPSR1 TT risk genotype carriers vs. adolescent A allele carriers displayed a reduced fronto-amygdala and fronto-insula effective connectivity suggesting basis of risk-increasing effect of the NPSR1T allele for anxiety.

  3. Sequence variation in NPSR1 may contribute to sex differences in stress regulation.

  4. we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5, HPGDS, and NPSR1) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS and NPSR1 in plasma.

  5. The interaction between 5-HTT (LL) and BDNF (A+) increased the risk of anxiety, and the interaction between BDNF (A+, GG) and NPSR1 (AA, T+) increased the risk of depression in asthmatic patients.

  6. findings demonstrate that hNPS-(1-10) is a biased agonist favoring Galphaq-dependent signaling. It may represent a valuable chemical probe for further investigation of the therapeutic potential of human NPS receptor-directed signalingin vivo.

  7. anxiety sensitivity correlated negatively with prefrontal activity in NPSR1 rs324981 carriers possibly suggesting a decompensation of the adaptive compensatory upregulation

  8. Results suggest the functional NPSR1 gene A/T variant to influence glutamate+glutamine concentrations in the bilateral anterior cingulate cortex in healthy male subjects during CCK-4 induced panic

  9. The T-allele of the NPSR1 rs324981 polymorphism is associated with increased impulsivity and ADHD-related traits in non-clinical cohorts.

  10. The results suggest neuropeptide S receptor gene variation to be associated with alterations of prefrontal functioning in the attentional functions alerting and executive control partly modulated by anxiety sensitivity.

  11. Results show that NPSR1 polymorphism is associated with AUD and alcohol consumption, dependent on sex, environment and age.

  12. gene polymorphism is a risk factor for high IgE-associated atopic eczema at the age of two years in Finland if there is no probiotic treatment

  13. The functional SNP rs324981 located in the gene of NPSR1 was significantly associated with objectively obtained sleep parameters in a sample of elderly white subjects

  14. results suggest a potential protective function of the NPSR1 rs324981 A/A genotype against pathologically enhanced anxiety that might be explained by stronger reflective prefrontal regulation over the subcortical fear response.

  15. Genetic variation at the NPSR1 locus impacts children's predisposition to ecurrent abdominal pain episodes in a Swedish population.

  16. study provides first evidence for the assumption that a NPSR1 variant modulates brain activation under stress, interacting with the environmental risk factor urban upbringing

  17. In the Estonian population, NPSR1 A/T polymorphism together with environmental factors is associated with anxious, depressive and activity-related traits, increased prevalence of affective/anxiety disorders and a higher likelihood of suicidal behaviour.

  18. NPSR1 A/T polymorphism is associated with impulsivity, ADHD symptoms and personality, mirroring the activity- and anxiety-mediating role of NPSR1.

  19. Neuropeptide S receptor 1 (NPSR1) activates cancer-related pathways and is widely expressed in neuroendocrine tumors.

  20. Differential gene-environment effects of the NPSR rs324981 T allele indicate recent life events with respect to anxiety sensitivity.

Rhesus Monkey Neuropeptide S Receptor 1 (NPSR1) interaction partners

  1. GPRA variants are not an important contributor to childhood asthma and atopy susceptibility in a Mexican population.

Profil protéine NPSR1

Profil protéine

This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Gene names and symbols associated with NPSR1

  • neuropeptide S receptor 1 (Npsr1)
  • neuropeptide S receptor 1 (NPSR1)
  • 9330128H10Rik Protéine
  • ASRT2 Protéine
  • GPR154 Protéine
  • GPRA Protéine
  • MVTR Protéine
  • NPSR Protéine
  • PGR14 Protéine
  • RGD1564154 Protéine
  • VRR1 Protéine

Protein level used designations for NPSR1

G protein-coupled receptor 154 , G protein-coupled receptor PGR14 , G-protein coupled receptor 154 , G-protein coupled receptor PGR14 , neuropeptide S receptor , vasotocin receptor , G protein-coupled receptor for asthma susceptibility , G-protein coupled receptor for asthma susceptibility , vasopressin receptor-related receptor 1

GENE ID SPECIES
319239 Mus musculus
300458 Rattus norvegicus
387129 Homo sapiens
574355 Macaca mulatta
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