anti-Neutrophil Cytosolic Factor 2 (NCF2) Anticorps

NCF2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain NCF2 NCF2 4688 P19878
Anti-Souris NCF2 NCF2 17970 O70145
Anti-Rat NCF2 NCF2 364018 A7E3N2
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Top anti-NCF2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 57 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-NCF2 Antibody Titration: 1.0 ug/ml Positive Control: MCF7 Whole Cell 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunofluorescence: p67phox/NOXA2 Antibody [NBP1-82542] - Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm. Western Blot: p67phox/NOXA2 Antibody [NBP1-82542] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Porcine Spleen lysate; Primary Ab: 5µg/ml Rabbit Anti-Human NCF2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Connectez-vous pour afficher 15 to 18 Days
$314.00
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Spleen, Neutrophils (formalin-fixed, paraffin-embedded) stained with NCF2 antibody ABIN305776 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$727.83
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Souris Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Mouse Spleen lysate; Primary Ab: 2µg/ml Rabbit Anti-Mouse NCF2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Connectez-vous pour afficher 13 to 16 Days
$324.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IP, WB Immunohistochemistry of paraffin-embedded mouse heart using NCF2 antibody at dilution of 1:100 (400x lens). 100 μL Connectez-vous pour afficher 16 Days
$334.02
Détails
Humain Lapin Inconjugué IC, IF, IP, IHC, WB Immunofluorescent analysis of p67 phox staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo Immunohistochemical analysis of p67 phox staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with th 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IP, ELISA, WB Human NCF2 / NCF-2 / P67phox Western blot (WB) 13611 100 μg Connectez-vous pour afficher 20 to 21 Days
$218.90
Détails
Souris Lapin Inconjugué IHC, WB Immunofluorescence analysis of HeLa cell using NCF2 antibody. Blue: DAPI for nuclear staining. 100 μL Connectez-vous pour afficher 13 to 14 Days
$357.50
Détails

anti-NCF2 Anticorps mieux référencés

  1. Human Polyclonal NCF2 Primary Antibody pour ICC, IF - ABIN4343179 : Lomnytska, Becker, Bodin, Olsson, Hellman, Hellström, Mints, Hellman, Auer, Andersson: Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value. dans British journal of cancer 2011 (PubMed)

Plus d’anticorps contre NCF2 partenaires d’interaction

Pig (Porcine) Neutrophil Cytosolic Factor 2 (NCF2) interaction partners

  1. analysis of NCF2, BCKDHB (Montrer BCKDHB Anticorps) and BCKDHA (Montrer BCKDHA Anticorps) in pig

Human Neutrophil Cytosolic Factor 2 (NCF2) interaction partners

  1. We analyzed the clinical and laboratory findings of CGD (Montrer CYBB Anticorps) with mutations in the NCF2 gene from amongst our cohort of CGD (Montrer CYBB Anticorps) patients. A homozygous mutation (c.835_836delAC, p.T279fsX294), a deletion in NCF2 gene was found in two cases. In the third case, two heterozygous mutations were detected, IVS13-2A>T on one allele and c.1099C>T (p.) on the other allele.

  2. All investigated patients presented the same mutation (c.257 + 2T > C) in NCF2 gene. We show that this mutation is responsible for a drastic decrease of p67phox mRNA and leads to the skipping of exon 3 detected in the low amount of residual mRNA.

  3. Phosphoinositol 3-phosphate regulates reactive oxygen species production by maintaining p40phox (Montrer NCF4 Anticorps) and p67phox at the phagosomal membrane.

  4. TLR4 (Montrer TLR4 Anticorps)- and TLR2-induced IRAK (Montrer IRAK1 Anticorps)-ERK (Montrer EPHB2 Anticorps) pathway cross-talks with p67phox-Nox-2 (Montrer CYBB Anticorps) for reactive oxygen species generation, thus regulating IL-1beta (Montrer IL1B Anticorps) transcription and processing in monocytic cells.

  5. Skeletal muscle protein expression of the NADPH oxidase (Montrer NOX1 Anticorps) subunits p22(phox (Montrer CYBA Anticorps)), p47(phox), and p67(phox) was increased in obese relative to lean subjects, where p22(phox (Montrer CYBA Anticorps)) and p67(phox) expression was attenuated by exercise training in obese subjects.

  6. A novel homozygous mutation in NCF2.

  7. results reveal an essential role for the Cys (Montrer DNAJC5 Anticorps)-Gly-Cys (Montrer DNAJC5 Anticorps) triad in Nox2 (Montrer CYBB Anticorps) in binding p67(phox), seconded by an additional binding region, comprising residues C terminal to Cys (Montrer DNAJC5 Anticorps)-Gly-Cys (Montrer DNAJC5 Anticorps). The 2 regions interact with distinct partner sites in p67(phox).

  8. This model assigns a central role to Arg-395 in the structure and stability of the quaternary NCF2/NCF4 (Montrer NCF4 Anticorps)/VAV1 (Montrer VAV1 Anticorps)/RAC1 NADPH oxidase (Montrer NOX1 Anticorps) complex.

  9. Data indicate that arachidonic acid induces the direct interaction of Rac (Montrer AKT1 Anticorps)-GTP (Montrer AK3 Anticorps)-bound p67(phox) with the C-terminal cytosolic region of phagocyte NADPH oxidase (Montrer NOX1 Anticorps) Nox2 (Montrer CYBB Anticorps).

  10. Four novel mutations in the NCF1 (Montrer NCF1 Anticorps), NCF2, and CYBB (Montrer CYBB Anticorps) genees have been identified in chronic granulomatous disease patients in Morocco.

Mouse (Murine) Neutrophil Cytosolic Factor 2 (NCF2) interaction partners

  1. Just as patients with chronic granulomatous disease who lack NADPH oxidase (Montrer NOX1 Anticorps) rarely develop SLE, NCF-2-null mice on a nonautoimmune background were susceptible to a chronic granulomatous disease-like opportunistic infection but did not develop lupus. In contrast, on a lupus-prone background, even haploinsufficiency of NCF-2 accelerated the development of full-blown lupus disease.

  2. p67(phox) binds to phosphoPrdx6 and inhibits its PLA2 (Montrer PLA2G2A Anticorps) activity, an interaction that could function to terminate the PLA2 (Montrer PLA2G2A Anticorps)-mediated NOX2 (Montrer CYBB Anticorps) activation signal.

  3. The results of this study suggested that repeated stress promotes depressive behavior through the upregulation of NADPH (Montrer FDXR Anticorps) oxidasesubunit (67kDa (Montrer RPSA Anticorps)) and the resultant metabolic oxidative stress.

  4. Data suggest that a cytosolic source of reactive oxygen species, probably p67(phox) subunit of cardiac NADPH oxidase 2 (NOX2 (Montrer CYBB Anticorps)), may contribute to the hypertrophic phenotype in glucose transporter 4 gene (GLUT4 (Montrer SLC2A4 Anticorps)-/-) mice.

  5. This report evaluates neutrophil cytosolic factor 2 (Ncf2) as a candidate Salmonella susceptibility gene for Ity3.

  6. This study demonstrates the involvement of ROS (Montrer ROS1 Anticorps) from NADPH oxidase (Montrer NOX1 Anticorps) in mediating paraquat cytotoxicity in BV-2 microglial cells and this process is mediated through PKCdelta (Montrer PKCd Anticorps)- and ERK (Montrer EPHB2 Anticorps)-dependent pathways.

NCF2 profil antigène

Profil protéine

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with NCF2

  • neutrophil cytosolic factor 2 (NCF2) anticorps
  • neutrophil cytosolic factor 2 L homeolog (ncf2.L) anticorps
  • neutrophil cytosolic factor 2 (ncf2) anticorps
  • neutrophil cytosolic factor 2 (p67phox) anticorps
  • neutrophil cytosol factor 2 (VDBG_06643) anticorps
  • hypothetical protein (PGTG_05816) anticorps
  • neutrophil cytosolic factor 2 (LOC100136240) anticorps
  • neutrophil cytosolic factor 2 (Ncf2) anticorps
  • MGC81877 anticorps
  • Ncf-2 anticorps
  • NOXA2 anticorps
  • P67-PHOX anticorps
  • P67PHOX anticorps
  • zgc:158405 anticorps

Protein level used designations for NCF2

neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2) , neutrophil cytosolic factor 2 , neutrophil cytosol factor 2 , predicted neutrophil cytosolic factor 2 , p67phox , p67-phox , NADPH oxidase cytosolic protein p67phox , NADPH oxidase cytosolic protein , 67 kDa neutrophil oxidase factor , NADPH oxidase activator 2 , chronic granulomatous disease, autosomal 2 , neutrophil NADPH oxidase factor 2 , neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2) , NADPH oxidase subunit (67 kD) , NADPH oxidase subunit (67kDa) , NCF-2

GENE ID SPECIES
424445 Gallus gallus
444487 Xenopus laevis
457573 Pan troglodytes
480036 Canis lupus familiaris
562473 Danio rerio
619224 Ciona intestinalis
619367 Xenopus (Silurana) tropicalis
9537124 Verticillium alfalfae VaMs.102
10531323 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100008802 Oryctolagus cuniculus
100136240 Oncorhynchus mykiss
100142665 Sus scrofa
100174692 Pongo abelii
100270811 Salmo salar
4688 Homo sapiens
17970 Mus musculus
364018 Rattus norvegicus
281346 Bos taurus
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