anti-Neutrophil Cytosolic Factor 4, 40kDa Anticorps
The protein encoded by NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense.
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anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Internal Region) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (pTyr243) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 260-289), (C-Term) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (N-Term) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Middle Region) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (C-Term) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 115-170) anticorps Primary Antibody
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anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Center) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 90-170) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 90-170), (pThr154) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Thr117) anticorps Primary Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) anticorps Primary Antibody
Neutrophil Cytosolic Factor 4, 40kDa (NCF4) profil antigène
Profil protéine
The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene names and symbols associated with NCF4
- neutrophil cytosolic factor 4 (ncf4) anticorps
- neutrophil cytosolic factor 4 (Ncf4) anticorps
- neutrophil cytosolic factor 4 (NCF4) anticorps
- AI451400 anticorps
- NCF anticorps
- P40PHOX anticorps
- SH3PXD4 anticorps
Protein level used designations for NCF4
p40phox protein , neutrophil cytosolic factor 4 , NADPH oxidase cytosolic protein p40phox , NCF-4 , neutrophil NADPH oxidase factor 4 , neutrophil cytosol factor 4 , p40-phox , SH3 and PX domain-containing protein 4
| GENE ID | SPECIES |
|---|---|
| 445891 | Takifugu rubripes |
| 100136241 | Oncorhynchus mykiss |
| 17972 | Mus musculus |
| 500904 | Rattus norvegicus |
| 4689 | Homo sapiens |
| 481277 | Canis lupus familiaris |
| 507859 | Bos taurus |
| 100009359 | Oryctolagus cuniculus |