anti-Nicotinamide N-Methyltransferase (NNMT) Anticorps

N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. De plus, nous expédions NNMT Protéines (17) et NNMT Kits (10) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
NNMT 4837 P40261
NNMT 18113 O55239
NNMT 300691  
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Top anti-NNMT Anticorps sur anticorps-enligne.fr

Showing 10 out of 112 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-NNMT Antibody Titration:  2.5ug/ml  Positive Control:  HepG2 cell lysate 100 μL 2 to 3 Days
$249.00
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Chien Souris Inconjugué FACS, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg 6 to 7 Days
$429.87
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg 6 to 7 Days
$429.87
Détails
Humain Lapin Inconjugué WB 100 μg 2 to 3 Days
$265.00
Détails
Humain Lapin Inconjugué ICC, IHC, WB 100 μL 13 to 16 Days
$245.00
Détails
Humain Souris Inconjugué FACS, IF, IHC, IHC (p), WB Anti-NNMT antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. 100 μL 11 to 14 Days
$639.83
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB Anti-NNMT antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. O ... 100 μL 11 to 14 Days
$639.83
Détails
Humain Souris Inconjugué IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NNMT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NNMT. Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-NNMT mouse monoclonal antibody. (ABIN2454303) 0.1 mL 2 to 3 Days
$482.90
Détails

anti-NNMT Anticorps mieux référencés

  1. Human Polyclonal NNMT Primary Antibody pour IHC (p), ELISA - ABIN543155 : Roessler, Rollinger, Palme, Hagmann, Berndt, Engel, Schneidinger, Pfeffer, Andres, Karl, Bodenmüller, Rüschoff, Henkel, Rohr, Rossol, Rösch, Langen, Zolg, Tacke: Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2005 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal NNMT Primary Antibody pour FACS, ICC - ABIN4339635 : Chen, Wang, Huang, Yong, Shen, Tang, Zhu, Ni, Feng: Nicotinamide N-methyltransferase: a potential biomarker for worse prognosis in gastric carcinoma. dans American journal of cancer research 2016 (PubMed)
    Show all 2 Pubmed References

  3. Dog (Canine) Polyclonal NNMT Primary Antibody pour WB - ABIN2775335 : Ulanovskaya, Zuhl, Cravatt: NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink. dans Nature chemical biology 2013 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre NNMT partenaires d’interaction

Human Nicotinamide N-Methyltransferase (NNMT) interaction partners

  1. The results of this study demonstrate a novel correlation between the NNMT expression level and patient survival, suggesting that NNMT has the potential to become a new prognostic biomarker to predict the treatment outcomes of the clinical chemotherapy in breast cancer.

  2. The metabolism-regulatory activity of NNMT depends on the precursor substrate methionine and the presence of IL6.

  3. Polymorphisms in rs694539-NNMT gene (mutant AA-genotype) could be a genetic risk factor for developing NAFLD and NASH (indicating susceptibility for progression and complications).

  4. This sudu used a combination of site-directed mutagenesis, kinetics, and circular dichoism experiments to demonstrate that citrullination of R132 leads to a structural perturbation that ultimately promotes NNMT inactivation.

  5. Results obtained showed significantly (P<0.0001) higher NNMT expression in melanoma compared with that detected in nevi. In addition, a significant (P<0.05) inverse relationship was found between enzyme levels and Breslow thickness, Clark level, the presence/number of mitoses, and ulceration.

  6. TGF-beta1 is significantly overexpressed in tumor tissue samples of clear cell Renal cell carcinoma patients. TGF-beta1 up-regulation could be responsible for the high levels of NNMT observed in clear cell Renal cell carcinoma tissues.

  7. Our data indicate that NNMT is a promising biomarker that could be used to support the early and noninvasive diagnosis of Bladder cancer

  8. Here we explored the association between NNMT gene polymorphisms and obesity. The subjects were recruited from male Chinese Han college student... the variation of the tagSNP, rs10891644, is significantly associated with obesity and the GT carriers are the susceptible population

  9. our results suggest that the ZEB1/NNMT signaling axis induces phenotypic and metabolic plasticity, as well as mesenchymal gene expression in ovarian cancer cells upon chronic glucose deprivation

  10. We demonstrate that NNMT outcompetes leucine carboxyl methyl transferase 1 (LCMT1) for methyl transfer from principal methyl donor SAM in biological systems. Inhibiting NNMT increased the availability of methyl groups for LCMT1 to methylate PP2A, resulting in the inhibition of oncogenic serine/threonine kinases (STK).

  11. High expression level of NNMT is associated with pancreatic cancer.

  12. This finding, for the first time, suggests the involvement of the NNMT gene rs694539 variant in the etiology of epilepsy.

  13. this study provides the first demonstration that NNMT plays a role in the resistance to 5-fluorouracil in colorectal cancer cells

  14. We suggest that lymph node metastatic adenoid cystic carcinoma (AdCC) cells acquire cancer stem cell features involving the up-regulation of NNMT and the loss of gap junction protein alpha-1, leading to epithelial-mesenchymal transition and consequent AdCC metastasis.

  15. Progression of pulmonary hypertension is associated with the activation of the NNMT-1-methylnicotinamide pathway.

  16. no SNP in NNMT is significantly associated with performance in 50-m run but rs2256292 is significantly associated with performance in 1000-m run in male Chinese college students

  17. These findings indicate that the repression of NNMT may underlie nickel-induced H3K9 dimethylation by altering the cellular SAM/SAH ratio.

  18. NNMT expression is significantly upregulated in human masticatory mucosa during wound healing

  19. The results show that a SNP (rs1941404) in NNMT is significantly associated with hyperlipidemia, and the influence of rs1941404 variation on the resting energy expenditure may be the possible mechanism for rs1941404 variation to induce hyperlipidemia.

  20. NNMT gene rs694539 variant is a genetic risk factor for migraine in women.

Mouse (Murine) Nicotinamide N-Methyltransferase (NNMT) interaction partners

  1. These data indicate that NNMT links the NAD(+) and methionine metabolic pathways and promotes liver steatosis and fibrosis.

  2. by co-opting the enzymes of the methionine cycle, Nnmt aids the recycling of homocysteine to S-adenosylmethionine for another round of methylation.

  3. Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide have been presented.

  4. NNMT is a novel regulator of histone methylation, polyamine flux and NAD(+)-dependent SIRT1 signalling, and is a unique and attractive target for treating obesity and type 2 diabetes

  5. Brain NNMT expression was not altered in hyperhomocysteinemia.

  6. Adipose tissue is a source of nicotinamide N-methyltransferase and homocysteine.

  7. the progression of vascular inflammation and atherosclerosis was associated with the upregulation of hepatic nicotinamide N-methyltransferase activity and subsequent increase in endogenous MNA plasma levels

NNMT profil antigène

Profil protéine

N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.

Gene names and symbols associated with NNMT

  • nicotinamide N-methyltransferase S homeolog (nnmt.S) anticorps
  • nicotinamide N-methyltransferase (CNG02680) anticorps
  • nicotinamide N-methyltransferase (AFUA_1G17750) anticorps
  • nicotinamide N-methyltransferase (AOR_1_1132194) anticorps
  • nicotinamide N-methyltransferase (AOR_1_1124014) anticorps
  • nicotinamide N-methyltransferase (CC1G_02598) anticorps
  • nicotinamide n-methyltransferase (VDBG_08111) anticorps
  • nicotinamide N-methyltransferase (TERG_00572) anticorps
  • nicotinamide N-methyltransferase (Tsp_04293) anticorps
  • Nicotinamide N-methyltransferase (nnmt) anticorps
  • nicotinamide N-methyltransferase (NNMT) anticorps
  • nicotinamide N-methyltransferase (Nnmt) anticorps
  • Afu1g17750 anticorps
  • AO090026000620 anticorps
  • MGC64498 anticorps
  • nnmt anticorps

Protein level used designations for NNMT

nicotinamide N-methyltransferase , nicotinamide n-methyltransferase , Nicotinamide N-methyltransferase

GENE ID SPECIES
379432 Xenopus laevis
3258655 Cryptococcus neoformans var. neoformans JEC21
3510174 Aspergillus fumigatus Af293
5988105 Aspergillus oryzae RIB40
5994073 Aspergillus oryzae RIB40
6016766 Coprinopsis cinerea okayama7130
9529830 Verticillium alfalfae VaMs.102
10374048 Trichophyton rubrum CBS 118892
10905204 Trichinella spiralis
100286563 Salmo salar
4837 Homo sapiens
489396 Canis lupus familiaris
100144485 Sus scrofa
18113 Mus musculus
300691 Rattus norvegicus
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