NPC1 Kits ELISA

NPC1 encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.

Qualité de données
  • 1
Type
  • 5
    Kit
Antigène
  • 5
Réactivité
  • 1
  • 1
  • 1
  • 1
  • 1
Application
  • 5
Type de méthode
  • 2
Analytical Method
  • 5
Méthode de détection
  • 5
Plate
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Sample
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5 Produits
Pre-coated, Type d'échantillon: Serum, Plasma, Tissue Homogenate, Cell Lysate
ReactivitéSouris
Méthode de détectionColorimetric, Sandwich ELISA
Portée de detection31.25-2000 pg/mL
Détails de la commande Cat. No. ABIN846124
$910.56
Plus shipping costs $45.00
Envoi sous 15 à 18 jours ouvrables
Pre-coated, Type d'échantillon: Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
ReactivitéMouton
Méthode de détectionColorimetric,
Portée de detectionQuantitative
Détails de la commande Cat. No. ABIN1056424
$707.14
96 tests
Plus shipping costs $45.00
Envoi sous 15 à 18 jours ouvrables
Pre-coated, Type d'échantillon: Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
ReactivitéSinge
Méthode de détectionColorimetric,
Portée de detectionQuantitative
Détails de la commande Cat. No. ABIN1056423
$707.14
96 tests
Plus shipping costs $45.00
Envoi sous 15 à 18 jours ouvrables
Pre-coated, Type d'échantillon: Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
ReactivitéPoulet
Méthode de détectionColorimetric,
Portée de detectionQuantitative
Détails de la commande Cat. No. ABIN1056422
$707.14
96 tests
Plus shipping costs $45.00
Envoi sous 15 à 18 jours ouvrables
ReactivitéHumain
Méthode de détectionColorimetric, Sandwich ELISA
Portée de detectionQuantitative
Détails de la commande Cat. No. ABIN2093811
$1,161.29
Plus shipping costs $45.00
Envoi sous 16 à 21 jours ouvrables
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NPC1 profil antigène

Profil protéine

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

Gene names and symbols associated with NPC1

  • NPC intracellular cholesterol transporter 1 (NPC1) anticorps
  • Niemann-Pick disease, type C1 (npc1) anticorps
  • Niemann-Pick C1 protein (LOC579887) anticorps
  • NPC intracellular cholesterol transporter 1 (Npc1) anticorps
  • A430089E03Rik anticorps
  • C85354 anticorps
  • Cdig2 anticorps
  • D18Ertd139e anticorps
  • D18Ertd723e anticorps
  • im:7149020 anticorps
  • lcsd anticorps
  • nmf164 anticorps
  • NPC anticorps
  • spm anticorps
  • wu:fb53a12 anticorps
  • wu:fc29a12 anticorps

Protein level used designations for NPC1

Niemann-Pick C1 protein , Niemann-Pick type C1 disease protein , Nasopharyngeal carcinoma 1 , Niemann-Pick C1 , Niemann-Pick disease, type C1 , sphingomyelinosis , Niemann-Pick C disease protein

GENE ID SPECIES
403698 Canis lupus familiaris
455338 Pan troglodytes
493693 Felis catus
553330 Danio rerio
579887 Strongylocentrotus purpuratus
100008746 Oryctolagus cuniculus
18145 Mus musculus
4864 Homo sapiens
397591 Sus scrofa
421076 Gallus gallus
266732 Rattus norvegicus
100718604 Cavia porcellus
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