anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) Anticorps

NFE2L1 encodes a protein that is involved in globin gene expression in erythrocytes. De plus, nous expédions NFE2L1 Kits (8) et NFE2L1 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
NFE2L1 4779 Q14494
NFE2L1 18023 Q61985
NFE2L1 360610  
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Top anti-NFE2L1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 70 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-NFE2L1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Spleen 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: NFE2L1 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml WB Suggested Anti-NFE2L1 Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: NFE2L1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis in mouse lung tissue lysates (35ug/lane) using NFE2L1  Antibody (C-term). This demonstrates this antibody detected the NFE2L1 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Détails
Boeuf (Vache) Lapin Inconjugué WB NFE2L1 (nuclear factor (erythroid-derived 2)-like 1) Antibody (against the middle region of NFE2L1) (50ug) validated by WB using Jurkat cell lysate at 0.2-1 ug/ml. 100 μL 2 to 3 Days
$319.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Souris Inconjugué ELISA, WB   100 μL Disponible
$363.46
Détails
Humain Lapin Inconjugué WB Western blot analysis in mouse lung tissue lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails
Humain Souris Inconjugué WB Western blot analysis of extracts of various cells, using NRF1 antibody. Western blot analysis of extracts of various cell lines, using NRF1 antibody (ABIN4905385) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s. 100 μL 11 to 13 Days
$433.51
Détails

Plus d’anticorps contre NFE2L1 partenaires d’interaction

Human Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) interaction partners

  1. study identified O-linked N-acetylglucosamine transferase (OGT) and host cell factor C1 (HCF-1) as two proteins capable of forming a complex with NRF1. O-GlcNAcylation catalyzed by OGT was essential for NRF1 stabilization and consequent upregulation of proteasome subunit genes

  2. Here, we tested the hypothesis that calpain-1 or -2 cleave TCF11/Nrf1. However, we did not find a role for calpain-1 or -2 in the activation of TCF11/Nrf1 after proteasome inhibition neither by using chemical inhibitors nor siRNA-mediated knockdown or overexpression of calpain subunits

  3. These findings indicate that NFE2L1(L) functions as a negative regulator of M1 polarization and pro-inflammatory response in macrophages

  4. The nascent Nrf1alpha (NFE2L1)/TCF11 polypeptide (non-glycosylated) is transiently translocated into the endoplasmic reticulum (ER).

  5. Low nuclear expression of Nrf1, high cytoplasmic expression of Nrf1, high nuclear expression of Nrf2 and low cytoplasmic expression of Keap1 are associated with adverse outcome in high-risk diffuse large B cell lymphomas treated with R-CHOEP

  6. Data show that Nrf1 can adopt several topologies within membranes that are determined by its NTD.

  7. Fbw7 as a regulator of Nrf1 expression and reveal a novel function of Fbw7 in cellular stress response.

  8. results indicate a novel role of Nrf1 in UVB-induced DNA damage repair and suggest Nrf1 as a tumor suppressor in the skin

  9. Data indicate both Nrf1a and Nrf1b isoforms transcripts were detected in different mouse and human cell lines, and in various mouse tissues.

  10. Nrf1 knockout resulted in the increased expression of GCLC and GCLM in human bronchial epithelial (HBE1) cells.

  11. while Nrf2 is crucial for MRE/ARE-mediated transcription in response to copper, Nrf1 may activate MT-1 expression by a mechanism different from that Nrf2 employs.

  12. Nrf1 physically interacts with androgen receptor and enhances it's DNA-binding activity, suggesting that the p65-Nrf1 isoform is a potential androgen receptor coactivator.

  13. The treatment with E2, Res, or VC significantly increased mRNA and protein expression levels of Nrf1.

  14. The results indicate that Nrf1 is a transcriptional activator of Herpud1 expression during ER stress, and they suggest Nrf1 is a key player in the regulation of the ER stress response in cells.

  15. This review outlines Nrf1 structure, function, regulation and its links to insulin resistance, diabetes and inflammation.

  16. Importantly, Nrf1 activity is positively and/or negatively regulated by distinct doses of proteasome and calpain inhibitors

  17. Together with molecular expression results, the authors thus suppose requirement of Nrf1alpha (and major derivates) for gene regulatory mechanisms repressing cancer cell process and malignant behaviour.

  18. These results uncover a new regulatory mechanism that USP15 activates Nrf1 against the beta-TrCP inhibition to maintain proteostasis.

  19. Here the authors show that the aspartyl protease DNA-damage inducible 1 homolog 2 (DDI2) is required to cleave and activate Nrf1.

  20. Nrf1 is regulated by O-GlcNAc transferase.

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) interaction partners

  1. Nrf1, RUVBL1, and TIP60 proteins were co-recruited to the promoter regions of proteasome genes after proteasome inhibitor treatments.

  2. Nrf1 (Nfe2l1) emerges as a novel guardian of brown adipocyte function, providing increased proteometabolic quality control for adapting to cold or to obesity.

  3. These findings indicate that NFE2L1(L) functions as a negative regulator of M1 polarization and pro-inflammatory response in macrophages

  4. Putative ubiquitination of Nrf1 (Nf2el1) is not a prerequisite necessary for involvement of p97 in the client processing.

  5. The nascent Nrf1alpha (NFE2L1)/TCF11 polypeptide (non-glycosylated) is transiently translocated into the endoplasmic reticulum (ER).

  6. Mechanistic studies revealed that Nfe2l1 deficiency may disturb the expression of lipolytic genes in adipocytes, leading to adipocyte hypertrophy followed by inflammation, pyroptosis, and insulin resistance.

  7. our investigation shows that the ER membrane protein TCF11/Nrf1 is an essential component of the cellular stress response mechanism. In response to cytotoxic stress, TCF11/Nrf1 is retrotranslocated and transferred to the nucleus where it induces proteasome subunit expression via binding to the ARE region of the relevant promoter.

  8. Deficiency of long isoforms of Nfe2l1 in pancreatic beta-cells increased susceptibility to acute arsenite-induced cytotoxicity by promoting arsenic biotransformation and intracellular MMA levels.

  9. Nrf1 is negatively regulated by its O-GlcNAcylation status that depends on the glucose concentrations

  10. Denervation induced proteasomal activation via NFE2L1 nuclear translocation in control mice

  11. This stduy identify the bZIP transcription factor Nfe2l1 and demonstrate that it promotes glial fate under direct Sox9 regulatory control.

  12. The study identifies casein kinase 2 as an NRF1-binding protein and finds that the knockdown of casein kinase 2 enhances the Nrf1-dependent expression of the proteasome subunit genes.

  13. Nrf1 plays an integral role in the maintenance of proteasome function in hepatocytes and in the prevention of liver steatosis development.

  14. findings suggest that nuclear-related factor erythroid 2 transcription factor (Nrf1) may play a role in maintaining genomic integrity, and that Nrf1 dysregulation may induce tumorigenesis

  15. The transcription factor, TCF11, is at the crossroads of oxidative stress and the ubiquitin proteasome system.

  16. Data show that nuclear factor erythroid-derived 2-related factor 1 (Nrf1), but not the related Nrf2, is necessary for induced proteasome gene transcription in mouse embryonic fibroblasts.

  17. the first in vivo experimental evidence that NFE2L1 produced by osteoblasts is involved in regulating osterix expression, osteoblast differentiation, and bone formation

  18. may promote cell survival by maintaining redox balance and protecting embryonic hepatocytes from TNF-mediated apoptosis during development

  19. the physical interaction between Nrf1 and C/EBPbeta provide a novel mechanism for the transcriptional regulation of DSPP in odontoblasts.

  20. Nrf1 is normally targeted to the endoplasmic reticulum membrane, and endoplasmic reticulum stress may play a role in modulating Nrf1 function as a transcriptional activator

NFE2L1 profil antigène

Profil protéine

This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.

Gene names and symbols associated with NFE2L1

  • nuclear factor, erythroid 2 like 1 (NFE2L1) anticorps
  • nuclear factor, erythroid derived 2,-like 1 (Nfe2l1) anticorps
  • nuclear factor, erythroid 2-like 1 (Nfe2l1) anticorps
  • nuclear factor, erythroid 2 like 1 (Nfe2l1) anticorps
  • nuclear factor, erythroid 2 like 1 S homeolog (nfe2l1.S) anticorps
  • nuclear factor, erythroid 2-like 1a (nfe2l1a) anticorps
  • AA408798 anticorps
  • AW212678 anticorps
  • LCR-F1 anticorps
  • Lcrf1 anticorps
  • nfe2l1 anticorps
  • NRF1 anticorps
  • TCF-11 anticorps
  • TCF11 anticorps

Protein level used designations for NFE2L1

NF-E2-related factor 1 , NFE2-related factor 1 , TCF-11 , locus control region-factor 1 , nuclear factor (erythroid-derived 2)-like 1 , nuclear factor erythroid 2-related factor 1 , nuclear factor, erythroid derived 2, like 1 , transcription factor 11 (basic leucine zipper type) , transcription factor HBZ17 , transcription factor LCR-F1 , nuclear factor erythroid 2-like 1 , nuclear factor, erythroid 2 like 1 S homeolog , nuclear factor, erythroid 2-like 1 , nrf1a , nuclear factor, erythroid derived 2,-like 1 , nuclear factor, erythroid derived 2,-like 1a , nuclear factor-like 1 , nuclear factor-like 1a protein

GENE ID SPECIES
4779 Homo sapiens
18023 Mus musculus
360610 Rattus norvegicus
417987 Gallus gallus
534582 Bos taurus
100172747 Pongo abelii
100716712 Cavia porcellus
379703 Xenopus laevis
405781 Danio rerio
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