anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) Anticorps

The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. De plus, nous expédions Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
NACC1 112939 Q96RE7
NACC1 66830 Q7TSZ8
NACC1 171454 O35260
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Top anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Anticorps sur anticorps-enligne.fr

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Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-BTBD14B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  721_B cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN190827 (0.5µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-BTBD14B Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Human Lung 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-BTBD14B Antibody Titration:  5.0ug/ml  Positive Control:  HepG2 cell lysate Human Intestine 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$610.50
Détails
Humain Souris Inconjugué ELISA, IHC, WB Figure 1: Western blot analysis using NACC1 mAb against HEK293 (1) and NACC1(AA: 165-438)-hIgGFc transfected HEK293 (2) cell lysate. Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues (left) and ovarian cancer tissues (right) using NACC1 mouse mAb with DAB staining. Dilution: 1/200 - 1/1000 100 μL Connectez-vous pour afficher 8 to 11 Days
$491.79
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Souris Inconjugué ELISA, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$522.50
Détails

anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Anticorps mieux référencés

  1. Human Polyclonal NACC1 Primary Antibody pour ELISA, WB - ABIN188846 : Wang, Rao, Chu, Shen, Levasseur, Theunissen, Orkin: A protein interaction network for pluripotency of embryonic stem cells. dans Nature 2006 (PubMed)

Plus d’anticorps contre Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing partenaires d’interaction

Human Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) interaction partners

  1. knockdown of HOXA9 abrogated NAC1induced drug resistance.

  2. NAC1 forms a protein complex to function as a transcriptional regulator in cancer cells

  3. a mutation in NACC1 causes microcephaly, profound developmental delays and/or intellectual disability, cataracts, severe epilepsy including infantile spasms, irritability, failure to thrive, and stereotypic hand movements

  4. miR-339-5p inhibits migration and invasion in ovarian cancer by targeting NACC1 and BCL6. miR-339-5p may be a biomarker of metastasis in ovarian cancer; NACC1 had a predictive value for ovarian cancer progression

  5. NAC1 has potential as a marker for distinguishing OED from CIS/OSCC

  6. NACC1 can be modified by SUMO paralogues, and cooperates with promyelocytic leukemia protein.

  7. strategy for the purification of tethered POZ domains that form forced heterodimers is described, and crystal structures of the heterodimeric POZ domains of Miz1/BCL6 and of Miz1/NAC1 are reported

  8. NAC1 is essential and sufficient for activation of FOXQ1

  9. low expression of NAC1 predicts poor prognosis for patients with pancreatic ductal adenocarcinoma.

  10. The identification of an NAC1 NLS thus clarifies the mechanism through which NAC1 translocates to the nucleus to regulate the transcription of genes involved in oncogenicity and pluripotency.

  11. Uterine sarcomas with NAC1 overexpression are clinically the most aggressive, chemoresistant, and radioresistant tumors.

  12. Results not only reveal a previously unrecognized function of NAC1, the molecular pathway involved and its impact on pathogenesis of tumor initiation and development, but also identify a novel senescence regulator

  13. NAC1 expression was significantly correlated with FASN expression in both OCCC samples and OCCC cell lines.

  14. NAC1 overexpression is critical to the growth and survival of cervical carcinomas irrespective of histologic type.

  15. NAC1 is identified as a novel regulator of autophagy

  16. These data suggest that the acetylation status of CTTN modulated by the NACC1-HDAC6 deacetylation system induces acceleration of melanoma cell migration activity via an actin-dependent cellular process

  17. Our data suggest that amplification at the ch19p13.2 NACC1 locus, leading to NAC1 overexpression, is one of the molecular genetic alterations associated with early tumor recurrence in ovarian cancer.

  18. These results indicate that a cell cycle-dependent regulatory mechanism controls NAC1 body formation in the nucleus and suggest that NAC1 body dynamics are associated with mitosis or cytokinesis.

  19. NAC1 is a potential stem cell pluripotency factor expression in normal endometrium, endometrial hyperplasia and endometrial carcinoma

  20. NAC1 over-expression is critical to the growth and survival of ovarian cancers. Furthermore, they suggest that NAC1 silencing RNA-induced phenotypes depend on the expression status of the targeted cell line.

Mouse (Murine) Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) interaction partners

  1. NAC1 downregulates the E-cadherin repressor ZEB1 directly via transcriptional repression.

  2. Nac1 overexpression promotes ESC proliferation and delays ESC differentiation in the absence of leukemia inhibitory factor (LIF). Furthermore, we demonstrated that Nac1 directly binds to the c-Myc promoter and regulates c-Myc transcription.

  3. a sub-network of four factors, Nac1, Oct4, Tcf3, and Sox2, regulates mouse embryonic stem cell differentiation into the alternative mesendodermal and neuroectodermal fates.

  4. The interaction of Nac1 with Miz1 may thus be relevant to its mechanism of tumourigenesis in ovarian cancer.

  5. NAC1 participates in the motility and differentiation of developing chondrocytes and cartilaginous tissues, and its expression is necessary to maintain normal axial patterning of murine skeleton.

  6. The mouse Nac1 gene consist of six exons, with exon 2 containing an alternative splice donor, providing a molecular explanation of the splice variants observed in mouse and rat.

  7. these data indicate involvement of NAC1 in the acute behavioral and neurochemical responses to psychomotor stimulants

  8. Nanog interacts with Nac1 through WNAAP to regulate the cell cycle of stem cells via the ERas/phosphatidylinositol 3-kinase/Akt pathway, but not pluripotency

Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) profil antigène

Profil protéine

This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9.

Gene names and symbols associated with NACC1

  • nucleus accumbens associated 1 (NACC1) anticorps
  • nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (Nacc1) anticorps
  • nucleus accumbens associated 1 (Nacc1) anticorps
  • 2010001H03Rik anticorps
  • 4930511N13Rik anticorps
  • BEND8 anticorps
  • Btbd14b anticorps
  • BTBD30 anticorps
  • Nac-1 anticorps
  • Nac1 anticorps
  • NACC1 anticorps

Protein level used designations for NACC1

BEN domain containing 8 , BTB/POZ domain-containing protein 14B , nucleus accumbens-associated protein 1 , transcriptional repressor NAC1 , nucleus accumbens associated 1, BEN and BTB (POZ) domain containing , BTB (POZ) domain containing 14B , NAC-1 , nucleus accumbens-1

GENE ID SPECIES
112939 Homo sapiens
484918 Canis lupus familiaris
525378 Bos taurus
66830 Mus musculus
171454 Rattus norvegicus
100063244 Equus caballus
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