anti-Nyctalopin (NYX) Anticorps

The product of NYX belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. De plus, nous expédions Nyctalopin Protéines (3) et Nyctalopin Kits (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
NYX 60506 Q9GZU5
NYX 236690 P83503
Anti-Rat NYX NYX 302516  
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Top anti-Nyctalopin Anticorps sur anticorps-enligne.fr

Showing 10 out of 29 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of Nyctalopin Antibody (N-term) in HL-60 cell line lysates (35ug/lane). NYX (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of NYX Antibody in HL-60 cell line lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of 293T cells, using NYX antibody. Immunohistochemistry of paraffin-embedded human prostate using NYX antibody at dilution of 1:100 (40x lens). 100 μL 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of 293T cells, using NYX antibody. Immunohistochemistry of paraffin-embedded human prostate using NYX antibody. 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué IHC, WB 100 μL 11 to 18 Days
$383.76
Détails
Humain Lapin Inconjugué ELISA, WB   200 μL 11 to 16 Days
$658.43
Détails
Humain Lapin Alkaline Phosphatase (AP) ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin APC ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin PE ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin Biotin ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails

Plus d’anticorps contre Nyctalopin partenaires d’interaction

Zebrafish Nyctalopin (NYX) interaction partners

  1. Nyctalopin is essential for synaptic transmission in the cone dominated zebrafish retina.

Human Nyctalopin (NYX) interaction partners

  1. Two Novel NYX Gene Mutations in the Chinese Families with X-linked Congenital Stationary Night Blindness were described.

  2. Four potential pathogenic variations in the NYX gene were found in four families with high myopia with or without CSNB1.

  3. Loss of ERG amplitude and apparent ON-pathway dysfunction at high temporal frequencies distinguish this patient with a Trp237Ter NYX mutation from those with other previously reported NYX mutations.

  4. A missense mutation (c.529_530GC>AT or p.Ala177Met) was identified in one male subject with high myopia, but not in 200 male emmetropes.

  5. A mutation was identified in NYX in 20 male patients with Congenital Stationary Night Blindness 1.

  6. The results expand the mutation spectrum of NYX, CACNA1F and GRM6. They also suggest that NYX mutations are a common cause of congenital stationary night blindness (CSNB).

  7. A proteomic search for proteins associated with nyctalopin in the retina identified TRPM1 as the binding partner and nyctalopin additionally interacts with mGluR6 receptor.

  8. Phenotypic expression of the complete type of X-linked congenital stationary night blindness in patients with different mutations in the NYX gene.

  9. Seven in-frame deletion, splicing, missense, nonsense, and frameshift mutations were identified segregating with X-linked congenital stationary night blindness in the NYX gene.

  10. Human and mouse nyctalopin are membrane-bound extracellular proteins and are functionally conserved.

  11. The results implicated a specific on-pathway signaling deficiency in CSNB1-NYX males with no evidence of off-pathway involvement. Likewise, rapid-on/off ramping stimuli also indicated that the functional deficit was localized to the on pathway.

  12. In a pool of eight diagnosed XLCSNB (X-linked congenital stationary night blindness) patients, five showed a sequence variation in the CACNA1F and two in the NYX gene.

  13. Results support a role for nyctalopin in synaptic transmission and/or synapse formation at ribbon synapses in the retina.

  14. Novel mutations of NYX were identified in two Chinese families with CSNB1 and myopia.

  15. Mutations in NYX may cause high myopia without congenital stationary night blindness.

  16. The c.855delG deletion in NYX seems to be a common mutation associated with CSNB in the Flemish population from Belgium.

  17. The nob (no b-wave) mouse model of CSNB1 (complete form of human X-linked congenital stationary night blindness) involves an 85-bp deletion in the nyx gene.

Mouse (Murine) Nyctalopin (NYX) interaction partners

  1. murine nyctalopin is anchored to the plasma membrane by a single transmembrane domain, such that the leucin-rich repeat domain is located in the extracellular space.

  2. The results of this study suggested that the nyctalopin is acting as an accessory TRP channel subunit critical for proper channel localization to the synapse.

  3. The nob phenotype is caused by an 85-bp deletion in the mouse nyx gene, which encodes the nyctalopin protein.

  4. These data suggest an important function of the Nyx protein in the inner retina and provide evidence that CSNB1 is based on a defect in the inner retinal circuitry.

  5. Human and mouse nyctalopin are membrane-bound extracellular proteins and are functionally conserved.

  6. Absence of nyctalopin does not disrupt the expression pattern of other proteins known to be required for synaptic transmission.

  7. No differences in nob mice and carriers suggesting equal susceptibility to light-induced photoreceptor degeneration.

Nyctalopin (NYX) profil antigène

Profil protéine

The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

Gene names and symbols associated with anti-Nyctalopin (NYX) Anticorps

  • nyctalopin (NYX) anticorps
  • nyctalopin L homeolog (nyx.L) anticorps
  • uncharacterized LOC491837 (LOC491837) anticorps
  • nyctalopin (nyx) anticorps
  • nyctalopin (Nyx) anticorps
  • CLNP anticorps
  • CLRP anticorps
  • CSNB1 anticorps
  • CSNB1A anticorps
  • CSNB4 anticorps
  • MGC84276 anticorps
  • NBM1 anticorps
  • nob anticorps
  • RGD1561300 anticorps

Protein level used designations for anti-Nyctalopin (NYX) Anticorps

nyctalopin , leucine-rich repeat protein , no b wave

GENE ID SPECIES
418566 Gallus gallus
447568 Xenopus laevis
473571 Pan troglodytes
491837 Canis lupus familiaris
568821 Danio rerio
100343596 Oryctolagus cuniculus
100585745 Nomascus leucogenys
100620950 Sus scrofa
60506 Homo sapiens
236690 Mus musculus
302516 Rattus norvegicus
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