Opsin 1 (Cone Pigments), Short-Wave-Sensitive Protéines (OPN1SW)

OPN1SW belongs to the G-protein coupled receptor 1 family, opsin subfamily. De plus, nous expédions OPN1SW Anticorps (6) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
OPN1SW 611 P03999
Rat OPN1SW OPN1SW 81644 Q63652
OPN1SW 12057 P51491
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
Détails
Wheat germ Humain Inconjugué   2 μg Connectez-vous pour afficher 11 to 12 Days
$491.43
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OPN1SW Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,

Mouse (Murine)

Plus protéines pour Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) partenaires d'interaction

Zebrafish Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) interaction partners

  1. found a 0.3-kb region between 0.6 and 0.3 kb 5' of the SWS2 initiation codon, encompassing four cone-rod homeobox (Montrer CRX Protéines)-binding sites (OTX sequences)

Guinea Pig Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) interaction partners

  1. Changes of opsin (Montrer RHO Protéines) expression might play a role in the occurrence of experimental myopia in guinea pig.

Human Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) interaction partners

  1. LVAVA haplotype of the OPN1LW gene and MVAVA haplotype of the OPN1MW (Montrer OPN1MW Protéines) gene cause apparently nonsyndromic high myopia in young patients but lead to progressive cone-rod dystrophy with deuteranopia and protanopia in middle-aged patients corresponding to a previously unknown disease course.

  2. Data suggest that insights into dimerization interface of red cone opsin should aid investigations of the structure and function of GPCR cell signaling.

  3. A novel homozygous PDE6C mutation was identified as the cause of ACHM. In addition, we identified an OPN1SW mutation in the sibling with complete achromatopsia.

  4. Individuals with the T190I S-opsin mutation behaved as mild tritans at 12.3-92.3Td, but as tritanopes at 1.2-9.2Td, for both light-adapted and dark-adapted conditions. The results are consistent with the mutant opsin (Montrer RHO Protéines) causing abnormal S-cone function.

  5. A novel mutation(prolin/leucine) in the short-wavelength-sensitive cone pigment gene associated with a tritan color vision defect.

  6. 11-cis (Montrer CISH Protéines)-retinol had no significant effect on the activity of human blue cone opsin

  7. Immunoreactivity to anti-OPN1SW antibodies was seen in the upper layer of human epidermis & reconstructed skin. The opsin (Montrer RHO Protéines) mRNA was seen in total RNA from human skin. Neither immunoreactivity nor mRNA expression was seen in cultured human keratinocytes.

Mouse (Murine) Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW) interaction partners

  1. These findings indicate that the aggregation of S-opsin induced by exposure to blue -emitting diode light causes endoplasmic reticulum stress, and ATF4 (Montrer ATF4 Protéines) activation in particular.

  2. quantitative FRET analysis in acutely isolated cone OS revealed that the cone degeneration-causing V268I mutation in peripherin-2 (Montrer PRPH2 Protéines) selectively reduced binding to M-opsin without affecting the peripherin-2 (Montrer PRPH2 Protéines) interaction to S-opsin or rhodopsin (Montrer RHO Protéines)

  3. Deletion of one allele of S-opsin from Lrat (Montrer LRAT Protéines)(-) (/-) mice (model of Leber congenital amaurosis) is sufficient to prevent rapid cone degeneration for at least 1 month. Deletion of both alleles of S-opsin prevents cone degeneration for at least 12 months.

  4. Thus, the three types of mouse opsin (Montrer RHO Protéines) appear distinctive in the degree to which their bleached, unregenerated opsins generate "dark light."

  5. Opn1sw is a target gene for RORbeta (Montrer RORB Protéines).

  6. TR beta (Montrer TXNRD2 Protéines) 2 and S opsin are expressed in cone photoreceptors only. Both are transcribed by E13, and their levels increase with cone genesis.

Profil protéine OPN1SW

Profil protéine

This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic.

Gene names and symbols associated with OPN1SW

  • opsin 1 (cone pigments), short-wave-sensitive 2 (opn1sw2)
  • opsin 1, short wave sensitive (OPN1SW)
  • blue-sensitive opsin (Blop)
  • KFH-B protein (kfh-b)
  • opsin 1 (cone pigments), short-wave-sensitive (opn1sw)
  • opsin 1, short wave sensitive (Opn1sw)
  • blue sensitive cone opsin (OPN2SW)
  • opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) (Opn1sw)
  • AW551857 Protéine
  • Bcp Protéine
  • Blop Protéine
  • bluops Protéine
  • BOP Protéine
  • CBT Protéine
  • CHK-2 Protéine
  • GB13493 Protéine
  • SI:zK13A21.5 (blue-sensitive opsin) Protéine
  • SWS1 Protéine
  • SWS2 Protéine
  • zfblue Protéine

Protein level used designations for OPN1SW

opsin-1, short-wave-sensitive 2 , opsin SWS-2 , blue-sensitive opsin , blue cone photoreceptor pigment , blue-sensitive visual pigment opsin , opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) , SWS1 opsin , short-wave sensitive type 1 opsin , violet cone opsin , short-wave-sensitive (color blindness, tritan) , violet-sensitive visual pigment , opsin CHK-2 , short-wave-sensitive opsin 1 , BOP , blue cone opsin-like pigment , s opsin , short wavelength-sensitive cone opsin , cone pigment , blue opsin , Blue cone photoreceptor pigment , Blue-sensitive opsin , Short-wave-sensitive opsin 1 , S opsin , SWS opsin , UV cone pigment , blue cone opsin , blue cone pigment , blue/UV opsin , short wavelength sensitive opsin

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