Ornithine Decarboxylase Antizyme 1 (OAZ1) Kits ELISA

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. De plus, nous expédions OAZ1 Anticorps (38) et OAZ1 Protéines (12) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
OAZ1 4946 P54368
OAZ1 18245 P54369
OAZ1 25502 P54370
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$736.84
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Souris < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
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Rat < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
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Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$1,029.60
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Poulet
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$1,095.60
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Plus Kits ELISA pour OAZ1 partenaires d'interaction

Human Ornithine Decarboxylase Antizyme 1 (OAZ1) interaction partners

  1. Data show the the interplay between the enzyme ornithine decarboxylase (ODC) and two regulatory proteins: antizyme (Az) and inhibitor (AzIN).

  2. the effects of AZ on cell growth are independent of polyamines.

  3. Results show that ornithine decarboxylase antizyme 1 (OAZ1) simultaneously inhibits the proliferation and induces the differentiation of oral cancer cells.

  4. To further understand its functions in CML pathogenesis, OAZ1 was overexpressed, and PCR array analysis was used to monitor the expression of key genes commonly involved in leukemia development.

  5. Gene expression studies have identified altered expression of ornithine decarboxylase antizyme 1 in suicide completers with a history of mood disorders.

  6. This study demomistrated that H3K4me3 modification plays an important role in up regulation of AOAZ1 in prefrontal cortex.

  7. In the absence of amino acids, mTORC1 is inhibited, whereas mTORC2 is activated, leading to the inhibition of global protein synthesis and increased AZ1 synthesis via a cap-independent mechanism.

  8. AZ_95-176 is the minimal AZ peptide that is fully functioning in the binding of ODC and AZI and inhibition of their function.

  9. the differences in residues 125 and 140 in ODC and AZI are responsible for the differential antizyme-binding affinities

  10. Data show that OAZ promotes the removal of Mps1 from centrosomes, and centrosome overproduction caused by reducing OAZ activity requires Mps1.

  11. These data together demonstrate the existence of a c-Jun-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

  12. Human AZI is capable of acting as a general inhibitor for all members of the antizyme family.

  13. Special polymorphism haplotype of OAZ gene is associated with Chinese systemic lupus erythematosus. OAZ may suggest a new pathway for lupus.

  14. This study also suggests that highly expressed AZI may be partly responsible for increased ODC activity and cellular transformation.

  15. OAZ can alter the intensity and duration of the BMP4 stimulus through Smad6

  16. Ornithine decarboxylase antizyme 1 enhances the ability of UM1 human oral squamous cancer cells to repair DNA double-strand breaks by the nonhomologous end-joining pathway.

  17. Identified the OAZ1+2222A/G polymorphism as a potential genetic marker of vascular events.

  18. Yeast antizyme mediates degradation of yeast ornithine decarboxylase by yeast but not by mammalian proteasome: new insights on yeast antizyme

  19. Data suggest that residue 331 may play a major role in the dimerization of AZI, and the mutating Ser-331 to Tyr in AZI (AZI-S331Y) caused a shift from a monomer configuration to a dimer.

  20. antizyme expression requires programmed, ribosomal frameshifting

Mouse (Murine) Ornithine Decarboxylase Antizyme 1 (OAZ1) interaction partners

  1. Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ).

  2. we have generated transgenic mice overexpressing mouse antizyme 1 gene under its own regulatory sequences

  3. Ornithine decarboxylase antizyme expression reduces tumor incidence, multiplicity and size even in the absence of p53.

  4. The activity of AZ1 was low in the virgin and involuting stages, but increased markedly during late pregnancy and early lactation.

  5. These data together demonstrate the existence of a c-Jun-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

  6. Testosterone treatment enhanced AZ1 and N1-SSAT mRNA levels in a time-dependent manner

  7. antizyme and glycosaminoglycans have roles in polyamine transport

  8. OAZ can alter the intensity and duration of the BMP4 stimulus through Smad6

  9. Az-1 has a central and meaningful role in modulation of polyamine homeostasis, and in regulating cellular proliferation and transformation properties.

  10. required for the proper formation of forebrain and hindbrain midline structures

  11. The data-driven docking results suggest that both proteins occupy the same binding site on Az1, with Az1 binding within a large groove in antizyme inhibitor (AzI) and Ornithine Decarboxylase (ODC).

  12. antizyme expression requires programmed, ribosomal frameshifting

Xenopus laevis Ornithine Decarboxylase Antizyme 1 (OAZ1) interaction partners

  1. antizyme expression requires programmed,+1 ribosomal frameshifting

OAZ1 profil antigène

Antigen Summary

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation.

Gene names and symbols associated with OAZ1

  • ornithine decarboxylase antizyme 1 (OAZ1) anticorps
  • ornithine decarboxylase antizyme 1 (Oaz1) anticorps
  • ornithine decarboxylase antizyme 1 S homeolog (oaz1.S) anticorps
  • ornithine decarboxylase antizyme 1a (oaz1a) anticorps
  • Antizyme anticorps
  • AZ-1 anticorps
  • AZ1 anticorps
  • AZI anticorps
  • AZS anticorps
  • oaz anticorps
  • oaz1 anticorps
  • ODC-Az anticorps
  • ODCAC anticorps

Protein level used designations for OAZ1

ODC-Az , antizyme 1 , ODC antizyme , ODC-Az-S , ornithine decarboxylase antizyme 1

GENE ID SPECIES
4946 Homo sapiens
18245 Mus musculus
25502 Rattus norvegicus
506973 Bos taurus
395746 Gallus gallus
379737 Xenopus laevis
101826304 Mesocricetus auratus
259192 Danio rerio
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