Oxysterol Binding Protein Protéines (OSBP)

Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008].. De plus, nous expédions Oxysterol Binding Protein Anticorps (63) et Oxysterol Binding Protein Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
OSBP 5007 P22059
OSBP 76303 Q3B7Z2
Rat OSBP OSBP 365410  
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Top Oxysterol Binding Protein Protéines sur anticorps-enligne.fr

Showing 5 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,376.85
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,376.85
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Escherichia coli (E. coli) Humain Inconjugué SDS-PAGE analysis of Human OSBP Protein. 100 μg 11 to 18 Days
$605.00
Détails

OSBP Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, , ,
Mouse (Murine)

Plus protéines pour Oxysterol Binding Protein (OSBP) partenaires d'interaction

Fruit Fly (Drosophila melanogaster) Oxysterol Binding Protein (OSBP) interaction partners

  1. Study identified an OSBP- and FAN-mediated sterol requirement in Drosophila spermatogenesis

Human Oxysterol Binding Protein (OSBP) interaction partners

  1. membrane cholesterol distribution contributes to insulin homeostasis at production, packaging, and export levels through the actions of OSBP and ABCs G1 and A1.

  2. the component proteins of the machinery, OSBP, VAP, SAC1, and PITPNB, are all essential host factors for AiV replication. Importantly, the machinery is directly recruited to the RNA replication sites through previously unknown interactions of VAP/OSBP/SAC1 with the AiV proteins and with ACBD3.

  3. results demonstrate that Sac1 expression in either the ER or Golgi apparatus has a minimal impact on the PI-4P that regulates OSBP activity or recruitment to contact sites

  4. Cholesterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP have been described.

  5. Data suggest that OSBP shifts the distribution of phosphatidylinositol 4-phosphate upon localization to endoplasmic reticulum-Golgi contact sites.

  6. Our results identify OspB as a regulator of mTORC1 and mTORC1-dependent cell proliferation early during S. flexneri infection and establish a role for IQGAP1 in mTORC1 signaling

  7. These results suggest that poliovirus proteins modulate PI4KB activity and provide PI4P for recruitment of OSBP to accumulate unesterified cholesterol on virus-induced membrane structure for formation of a virus replication complex.

  8. OSBP-mediated back transfer of phosphatidylinositol 4-phosphate might coordinate the transfer of other lipid species at the endoplasmic reticulum-Golgi interface.

  9. OSBP is required for efficient replication of intracellular S. Typhimurium.

  10. Data indicate that phosphorylation on two serine-rich motifs, S381-S391 (site 1) and S192, S195, S200 (site 2), specifically controls oxysterol-binding protein (OSBP) activity at the endoplasmic reticulum (ER).

  11. PKD negatively regulates HCV secretion/release by attenuating OSBP and CERT functions by phosphorylation inhibition. This study identifies the key role of the Golgi components in the HCV maturation process.

  12. Results identify a novel substrate of protein kinase D at the Golgi, the oxysterol-binding protein OSBP.

  13. This review summarizes recent evidence of sterol transfer activity by OSBP, suggesting seemingly disparate functions that could be the result of alterations in membrane sterol distribution or ancillary to this primary activity.

  14. Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies.

  15. OSBP was found to function as a cholesterol-binding scaffolding protein coordinating the activity of two phosphatases to control the extracellular signal-regulated kinase (ERK) signaling pathway

  16. Regulation of ceramide transport protein by OSBP, sterols, and vesicle-associated protein reveals a novel mechanism for integrating sterol regulatory signals with ceramide transport and phingomyelin synthesis in the Golgi apparatus.

  17. OSBP is able to sense both membrane cholesterol and oxidized sterols and link this information to the ERK1/2 signaling pathway.

  18. functional role of OSBP in the HCV maturation process.

Mouse (Murine) Oxysterol Binding Protein (OSBP) interaction partners

  1. OSBP may be a target and downstream effector of miR-124 for regulating neurite outgrowth and elongation.

  2. roles of different ORP proteins as regulators of macrophage lipid composition, with implications for inflammatory signaling

  3. Partitioning of Osbp between the endoplasmic reticulum and the Golgi apparatus is regulated by Vapa.

  4. OSBP opposes the activity of LXR by negatively regulating ABCA1 activity in the cytoplasm by sterol-binding domain-dependent protein destabilization

Rabbit Oxysterol Binding Protein (OSBP) interaction partners

  1. Oxysterol-binding protein is required for the perinuclear localization of intra-Golgi v-SNAREs.

Profil protéine Oxysterol Binding Protein (OSBP)

Profil protéine

Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase

Gene names and symbols associated with OSBP

  • Oxysterol binding protein (Osbp)
  • oxysterol binding protein (OSBP)
  • oxysterol binding protein (Osbp)
  • 1110018F06Rik Protéine
  • AW559088 Protéine
  • CG6708 Protéine
  • Dmel\\CG6708 Protéine
  • mKIAA4220 Protéine
  • osbp Protéine
  • OSBP-Dm Protéine
  • OSBP1 Protéine

Protein level used designations for OSBP

CG6708-PA , Osbp-PA , oxysterol binding protein , oxysterol-binding protein , oxysterol-binding protein 1

GENE ID SPECIES
42985 Drosophila melanogaster
5007 Homo sapiens
483448 Canis lupus familiaris
530000 Bos taurus
76303 Mus musculus
365410 Rattus norvegicus
451213 Pan troglodytes
100009048 Oryctolagus cuniculus
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