PDS5, Regulator of Cohesion Maintenance, Homolog A (S. Cerevisiae) Protéines (PDS5A)

The protein encoded by PDS5A binds to the cohesin complex and associates with chromatin through most of the cell cycle. De plus, nous expédions PDS5A Anticorps (63) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PDS5A 23244 Q29RF7
PDS5A 71521  
Rat PDS5A PDS5A 305343 A4L9P7
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
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PDS5A Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour PDS5, Regulator of Cohesion Maintenance, Homolog A (S. Cerevisiae) (PDS5A) partenaires d'interaction

Human PDS5, Regulator of Cohesion Maintenance, Homolog A (S. Cerevisiae) (PDS5A) interaction partners

  1. The results show that cohesin has an essential genome-wide function in mediating long-range chromatin interactions and support the hypothesis that cohesin creates these by loop extrusion, until it is delayed by CTCF in a manner dependent on PDS5 proteins, or until it is released from DNA by WAPL.

  2. These results provide the first evidence indicating a tumor suppressor role of SA1 (Montrer STAG1 Protéines) in early colon carcinogenesis

  3. By interacting with a unique domain of Esco1, Pds5 recruits Esco1 to chromatin-bound cohesin complexes to form cohesion.

  4. The data show a downregulation of proliferation-associated host gene PDS5A and suggest a role of PDS5A in HIV-1-induced cellular pathogenesis but not viral replication.

  5. Data show that the siRNA-mediated knockdown of Pds5A affects sister chromatid cohesion but does not influence mitotic checkpoint (Montrer BUB3 Protéines) function or the proliferation and survival of glioblastoma multiforme cells.

  6. Findings suggest that the SCC-112 gene expression is likely to be associated with normal cell growth and proliferation.

  7. SCC-112 improve cell proliferation and contributes to tumorigenesis by interacting with p63 (Montrer RPE65 Protéines) and promoting cell cycling.

Mouse (Murine) PDS5, Regulator of Cohesion Maintenance, Homolog A (S. Cerevisiae) (PDS5A) interaction partners

  1. While Pds5A(-/-) and Pds5B(-/-) mice die at birth, embryos harboring 3 mutant Pds5 alleles die between E11.5 and E12.5 most likely of heart failure, indicating that total Pds5 gene dosage is critical for normal development.

Profil protéine PDS5A

Profil protéine

The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PDS5A

  • PDS5 cohesin associated factor A (PDS5A)
  • PDS5 cohesin associated factor A S homeolog (pds5a.S)
  • PDS5 cohesin associated factor A (Pds5a)
  • PDS5 cohesin associated factor A (pds5a)
  • 9030416H16Rik Protéine
  • Aprin Protéine
  • E230024D05Rik Protéine
  • mKIAA0648 Protéine
  • PDS5A Protéine
  • pds5a-A Protéine
  • pds5a-B Protéine
  • RGD1307094 Protéine
  • Scc-112 Protéine
  • SCC112 Protéine
  • zgc:66331 Protéine
  • zgc:153878 Protéine

Protein level used designations for PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) , SCC-112 protein , sister chromatid cohesion protein PDS5 homolog A-A , sister chromatid cohesion protein PDS5 homolog A-B , sister chromatid cohesion protein Pds5A , cell proliferation-inducing gene 54 protein , sister chromatid cohesion protein 112 , sister chromatid cohesion protein PDS5 homolog A

GENE ID SPECIES
471172 Pan troglodytes
735137 Xenopus laevis
23244 Homo sapiens
479103 Canis lupus familiaris
533206 Bos taurus
71521 Mus musculus
305343 Rattus norvegicus
422787 Gallus gallus
393967 Danio rerio
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