anti-PDZ Domain Containing 1 (PDZK1) Anticorps

PDZK1 encodes a PDZ domain-containing scaffolding protein. De plus, nous expédions PDZK1 Kits (7) et PDZK1 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PDZK1 5174 Q5T2W1
PDZK1 59020 Q9JIL4
PDZK1 65144 Q9JJ40
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Top anti-PDZK1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 119 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PDZK1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate PDZK1 is supported by BioGPS gene expression data to be expressed in HepG2 WB Suggested Anti-PDZK1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate <br /> PDZK1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué ICC, IF, IHC, IHC (p), SimWes, WB 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$415.44
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PDZK1 Antibody [NBP1-82572] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & vesicles. Immunohistochemistry-Paraffin: PDZK1 Antibody [NBP1-82572] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with PDZK1 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of PDZK1 Antibody (Center) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the PDZK1 antibody detected the PDZK1 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: PDZK1 Antibody [NBP1-82573] - Staining of human kidney shows strong cytoplasmic and luminal positivity in tubular cells. Immunocytochemistry/Immunofluorescence: PDZK1 Antibody [NBP1-82573] - Staining of human cell line U-2 OS shows positivity in endoplasmic reticulum. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of A549 whole cell lysates, using PDZK1 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277517 at 1/100 staining Mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IF, WB Flow Cytometry: PDZK1 Antibody (1A2) [NBP2-22568] - Analysis of PDZK1 in Hep3B cell line, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line). Immunocytochemistry/Immunofluorescence: PDZK1 Antibody (1A2) [NBP2-22568] - Analysis of PDKZ1 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PDKZ1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). 0.1 mL Connectez-vous pour afficher 12 to 15 Days
$415.44
Détails
Humain Souris Inconjugué ELISA, IHC, IHC (p), WB Anti-PDZK1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μL Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails

anti-PDZK1 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal PDZK1 Primary Antibody pour ICC, IF - ABIN152917 : Lan, Silver: Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal PDZK1 Primary Antibody pour IHC (p), ELISA - ABIN562170 : Walker, MacLeod, Williams, Cameron, Smyth, Langdon: Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer. dans Gynecologic oncology 2007 (PubMed)

Plus d’anticorps contre PDZK1 partenaires d’interaction

Human PDZ Domain Containing 1 (PDZK1) interaction partners

  1. PDZK1 directly interacts with OATP2B1 (Montrer SLCO2B1 Anticorps) resulting in a change of the amount of transporter in the membrane, and thereby in an increased transport function.

  2. These findings have provided first lines of evidences that PDZK1 expression is negatively correlated with SHP-1 activation and poor clinical outcomes in clear cell renal cell carcinoma (ccRCC) . PDZK1 was identified as a novel tumor suppressor in ccRCC by negating SHP-1 activity

  3. HNF1alpha (Montrer HNF1A Anticorps), which has previously been described as a modulator of several transporters of the renal transportosome, is also a key determinant of PDZK1 transcription.

  4. a PDZK1 single nucleotide polymorphism rs12129861 was found to be significantly associated with gout susceptibility (meta-analysis)

  5. PDZK1 was defined as an independent prognostic factor for both OS and DFS (Montrer FST Anticorps). These findings indicated that low level of PDZK1 could predict poor clinical outcome in patients with ccRCC.

  6. Inflammation-induced loss of PDZK1 expression may contribute to the NHE3 (Montrer SLC9A3 Anticorps) dysfunction observed in the inflamed intestine.

  7. PARP (Montrer COL11A2 Anticorps) regulates estradiol-mediated cell growth by controlling the ER/IGF-1R (Montrer IGF1R Anticorps)/PDZK1 axis.

  8. PDZK1, negatively regulates 5-HT2AR endocytosis and has no effect upon 5-HT2AR-mediated ERK1/2 phosphorylation.

  9. Described is a structure of D-AKAP2 (Montrer AKAP10 Anticorps) in complex with two interacting partners and the exact mechanism by which a segment that on its own is disordered presents an alpha-helix to PKA and a beta (Montrer SUCLA2 Anticorps)-strand to PDZK1.

  10. PDZK1 and NHERF1 regulate the transport function of OATP1A2 by modulating protein internalization via a clathrin-dependent pathway and by enhancing protein stability.

Mouse (Murine) PDZ Domain Containing 1 (PDZK1) interaction partners

  1. Dysfunction of intestinal OCTN1 (Montrer SLC22A4 Anticorps) in mouse model of chronic kidney disease (CKD) impaired the OCTN1 (Montrer SLC22A4 Anticorps)-ergothioneine axis, an adaptive antioxidant system, and that decreased antioxidant ergothioneine levels may contribute to CKD progression in a PDZK1-dependent manner.

  2. These results suggest that the PDZ domain (Montrer INADL Anticorps) of PICK1 (Montrer PICK1 Anticorps) directly interacts with calcineurin B (Montrer CAN Anticorps) in osteoclast progenitor cells and promotes osteoclast differentiation through activation of calcineurin-NFAT (Montrer NFATC1 Anticorps) signaling.

  3. Inflammation-induced loss of PDZK1 expression may contribute to the NHE3 (Montrer SLC9A3 Anticorps) dysfunction observed in the inflamed intestine.

  4. PDZK1 has novel SR-BI (Montrer SCARB1 Anticorps)-independent function in VSM that affords protection from neointima formation, and this involves PDZK1 suppression of VSM cell proliferation via an inhibitory interaction with Bcr (Montrer BCR Anticorps)

  5. Data show that interaction of the inducible nitric oxide synthase (iNOS (Montrer NOS2 Anticorps)) C-terminus with the PDZ (Montrer INADL Anticorps) domains of EBP50 (Montrer SLC9A3R1 Anticorps) protein or Pdzk1 protein CAP70 resulted greater nitric oxide (NO) synthesis.

  6. PDZK1 regulates intracellular trafficking of Oatp1a1.

  7. PDZK1(NHERF3) is entirely non-raft associated with lipid rafts in brush border membrane fractions of NHE3 (Montrer SLC9A3 Anticorps).

  8. NHERF3 is a key regulator of organic transport in the kidney, particularly MRP4-mediated clearance of drug molecules.

  9. SR-BI (Montrer SCARB1 Anticorps) and PDZK1 protein and mRNA expression levels fell rapidly in primary hepatocyte cultures, indicating this system does not adequately mimic hepatocytes in vivo for analysis of the PDZK1 dependence of SR-BI (Montrer SCARB1 Anticorps).

  10. the localization of PDZK1 on hepatocyte cell surface membranes in vivo is dependent on its PDZ4 domain and the presence of SR-BI (Montrer SCARB1 Anticorps).

PDZK1 profil antigène

Profil protéine

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with PDZK1

  • PDZ domain containing 1 (PDZK1) anticorps
  • PDZ domain containing 1 L homeolog (pdzk1.L) anticorps
  • PDZ domain containing 1 (pdzk1) anticorps
  • PDZ domain containing 1 (Pdzk1) anticorps
  • 1700023D20Rik anticorps
  • 2610507N21Rik anticorps
  • 4921513F16Rik anticorps
  • AI267131 anticorps
  • AI314638 anticorps
  • AL022680 anticorps
  • CAP70 anticorps
  • Clamp anticorps
  • D3Ertd537e anticorps
  • mPDZK1 anticorps
  • NHERF-3 anticorps
  • NHERF3 anticorps
  • Pdzd1 anticorps
  • PDZK1 anticorps
  • xpdzk1 anticorps

Protein level used designations for PDZK1

PDZ domain containing 1 , Na(+)/H(+) exchange regulatory cofactor NHE-RF3-like , CFTR-associated protein of 70 kDa , Na(+)/H(+) exchange regulatory cofactor NHE-RF3 , PDZ-containing kidney protein 1 , na/Pi cotransporter C-terminal-associated protein 1 , naPi-Cap1 , sodium-hydrogen exchanger regulatory factor 3 , NHERF-3 , Na(+)/H(+) exchanger regulatory factor 3 , PDZ domain-containing protein 1 , PDZK1-like protein , C-terminal linking and modulating protein , C-terminal-linking and modulating protein , dietary Pi-regulated RNA-1 , diphor-1

GENE ID SPECIES
418460 Gallus gallus
446272 Xenopus laevis
696698 Macaca mulatta
100065636 Equus caballus
100145801 Xenopus (Silurana) tropicalis
100152549 Sus scrofa
100403156 Callithrix jacchus
100482698 Ailuropoda melanoleuca
100012609 Monodelphis domestica
100588075 Nomascus leucogenys
100611671 Pan troglodytes
5174 Homo sapiens
59020 Mus musculus
475823 Canis lupus familiaris
534439 Bos taurus
100008900 Oryctolagus cuniculus
65144 Rattus norvegicus
100173285 Pongo abelii
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