Profil protéine

Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002

Gene names and symbols associated with PDZD3

• PDZ domain containing 3 (Pdzd3) anticorps
• PDZ domain containing 3b (pdzd3b) anticorps
• PDZ domain containing 3 (PDZD3) anticorps

• IKEPP anticorps
• NaPi-Cap2 anticorps
• NHERF4 anticorps
• Pdzk2 anticorps
• RGD1559807 anticorps
• Afficher tous les alias de synonymes
• zgc:194812 anticorps

Protein level used designations for PDZD3

Na(+)/H(+) exchange regulatory cofactor NHE-RF4 , PDZ domain containing 3 , NHERF-4 , PDZ domain containing 2 , PDZ domain-containing protein 2 , PDZ domain-containing protein 3 , intestinal and kidney enriched PDZ protein , intestinal and kidney-enriched PDZ protein , na/Pi cotransporter C-terminal-associated protein 2 , naPi-Cap2 , natrium-phosphate cotransporter IIa C-terminal-associated protein 2 , sodium-hydrogen exchanger regulatory factor 4 , sodium-phosphate cotransporter IIa C-terminal-associated protein 2