anti-PR Domain Containing 5 (PRDM5) Anticorps

The protein encoded by PRDM5 is a transcription factor of the PR-domain protein family. De plus, nous expédions PRDM5 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PRDM5 11107 Q9NQX1
PRDM5 70779 Q9CXE0
PRDM5 689788  
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Top anti-PRDM5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 61 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-PRDM5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  721_B cell lysate Immunohistochemistry with Human Small Intestine tissue at an antibody concentration of 5.0ug/ml using anti-PRDM5 antibody 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PRDM5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  293T cell lysate 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  PRDM5  Sample Type:  ACHN Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PRDM5 antibody ABIN462186 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PRDM5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. ... 100 μL 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using PRDM5 antibody. Immunohistochemistry of paraffin-embedded rat spleen using PRDM5 antibody at dilution of 1:100 (x400 lens). 100 μL 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with PRDM5 antibody ABIN241580 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PRDM5 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$581.17
Détails
Humain Lapin Inconjugué IF, IHC, WB Western blot analysis of extracts of various cell lines, using PRDM5 antibody. Immunohistochemistry of paraffin-embedded rat spleen using PRDM5 antibody. 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué IHC (p), WB 50 μg 6 to 8 Days
$495.00
Détails
Humain Lapin Inconjugué WB Western blot analysis in MDA-MB231 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails

anti-PRDM5 Anticorps mieux référencés

  1. Human Monoclonal PRDM5 Primary Antibody pour CyTOF, ELISA - ABIN4347214 : Zhou, Chen, Li, Sun, Tan, Wang, Chu, Zhang, Cheng, Zhou, Wang, Yuan: Overexpression of PRDM5 promotes acute myeloid leukemia cell proliferation and migration by activating the JNK pathway. dans Cancer medicine 2019 (PubMed)

Plus d’anticorps contre PRDM5 partenaires d’interaction

Human PR Domain Containing 5 (PRDM5) interaction partners

  1. Truncations may be the primary mutation type in PITX2. Glaucoma onset may be earlier in patients with mutations in PITX2 than in those without mutations in PITX2 and FOXC1. A block of the anterior chamber angle by the end of the iris might represent the main factor influencing the development of glaucoma in ARS patients with an asymmetric aniridia phenotype.

  2. Inhibiting PRDM5 expression by siRNA attenuated the IFN-gamma-triggered accumulation of active caspase-3 and cleaved PARP in intestinal epithelial cells. Moreover, flow cytometry assay and CCK-8 analysis revealed that PRDM5 knockdown significantly alleviated the IFN-gamma-induced cellular apoptosis in HT29 cells.

  3. Both Prdm 4 and Prdm 5 are expressed in human corneal endothelium, primary hCECs and in HCECs-12 cells, characterised by expression of the Na(+)/K(+)-ATPase.

  4. The miR-182 promoter is rarely methylated in epithelial ovarian cancers (EOCs), and its methylation status is associated with lower miR-182 expression. Deletion of the PRDM5 locus may play a supportive role in miR-182 overexpression in EOC. miR-182 is an unfavorable prognostic factor in EOC.

  5. The current study revealed a novel mutation in the PRDM5 gene in a Brittle cornea syndrome (BCS) family and recurrent mutation in a sporadic BCS patient.

  6. Genetic variants in PRDM5 can lead to various syndromic and nonsyndromic disorders affecting the anterior segment of the eye.

  7. Defective interaction of PRDM5 with repressive complexes, and dysregulation of H3K9me2, play a role in PRDM5-associated disease.

  8. Reduced expression of PRDM5 was observed in the cornea and retina of brittle cornea syndrome patients.

  9. These data suggest that PRDM5 is a relevant tumour suppressor gene that is frequently targeted in colorectal tumourigenesis.

  10. PRDM2, PRDM5, PRDM16 promoters are methylated and their expression is suppressed in lung cancer cells.

  11. Data provide the first causal link between Prdm5 loss and intestinal carcinogenesis, and uncover an extensive and novel PRDM5 target repertoire likely facilitating the tumor-suppressive functions of PRDM5.

  12. Promoter methylation-mediated downregulation of PRDM5 contributes to the development of lung squamous cell carcinoma.

  13. Frequent epigenetic silencing of PRDM5 is involved in multiple tumorigeneses, which could serve as a tumor biomarker

  14. ZNF469 and PRDM5, two genes that when mutated cause brittle cornea syndrome, participate in the same regulatory pathway.

  15. Data show that reduced expression of PRDM5 may play an important role in the pathogenesis and/or development of cervical cancer, and is considered to be caused in part by aberrant DNA methylation.

  16. PRDM5 caused G2/M arrest and apoptosis upon infection of tumor cells. These results suggest that inactivation of PRDM5 may play a role in carcinogenesis.

  17. Results identify PRDM5, which acts as a sequence-specific, DNA binding transcription factor that targets hematopoiesis-associated protein-coding and microRNA genes, some of which are targets of Gfi1.

  18. Data suggest that epigenetic alteration of PRDM5 (e.g., methylation of its 5'-CpG island or trimethylation of Lys(27) of histone H3) likely plays a key role in the progression of gastrointestinal cancers and may be a useful molecular marker.

Zebrafish PR Domain Containing 5 (PRDM5) interaction partners

  1. Prdm5 is expressed specifically in the area of the forming neurocranium during craniofacial development.

  2. PRDM5 regulates the expression of components of both canonical and non canonical wnt pathways and negatively modulates wnt signaling in vivo

Mouse (Murine) PR Domain Containing 5 (PRDM5) interaction partners

  1. PRDM5 promotes the proliferation and invasion of murine melanoma cells through up-regulating JNK expression and strategies targeting PRDM5 may be promising for the therapy of melanoma.

  2. Data provide the first causal link between Prdm5 loss and intestinal carcinogenesis, and uncover an extensive and novel PRDM5 target repertoire likely facilitating the tumor-suppressive functions of PRDM5.

  3. These data indicate how Prdm5 modulates transcription by interacting with factors involved in genome organization in mouse embryonic stem cells.

  4. we show that Prdm5 controls both Collagen I transcription and fibrillogenesis by binding inside the Col1a1 gene body and maintaining RNA polymerase II occupancy

PRDM5 profil antigène

Profil protéine

The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis.

Gene names and symbols associated with PRDM5

  • PR/SET domain 5 (PRDM5) anticorps
  • PR/SET domain 5 (prdm5) anticorps
  • PR domain containing 5 (prdm5) anticorps
  • PR domain containing 5 (Prdm5) anticorps
  • PR/SET domain 5 (Prdm5) anticorps
  • 4432417F03Rik anticorps
  • 6530401I24Rik anticorps
  • AI197291 anticorps
  • BCS2 anticorps
  • E130112L17Rik anticorps
  • PFM2 anticorps
  • PRDM5 anticorps

Protein level used designations for PRDM5

PR domain containing 5 , PR domain zinc finger protein 5-like , PR domain zinc finger protein 5 , un-named hi61 , unm hi61 , PR domain-containing protein 5

GENE ID SPECIES
461462 Pan troglodytes
537500 Bos taurus
708790 Macaca mulatta
100072313 Equus caballus
100341114 Oryctolagus cuniculus
100447786 Pongo abelii
100481358 Ailuropoda melanoleuca
100522885 Sus scrofa
100560261 Anolis carolinensis
100583964 Nomascus leucogenys
100538934 Meleagris gallopavo
11107 Homo sapiens
432371 Danio rerio
422673 Gallus gallus
483850 Canis lupus familiaris
70779 Mus musculus
689788 Rattus norvegicus
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