Paired Box 7 Protéines (PAX7)

PAX7 is a member of the paired box (PAX) family of transcription factors. De plus, nous expédions PAX7 Anticorps (263) et PAX7 Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PAX7 5081 P23759
Rat PAX7 PAX7 500574  
PAX7 18509 P47239
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Showing 3 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,626.73
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,626.73
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

PAX7 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Paired Box 7 (PAX7) partenaires d'interaction

Turkey Paired Box 7 (PAX7) interaction partners

  1. These data suggested that expression of the myogenic regulatory transcription factors are dependent upon expression of glypican-1 and syndecan-4 during satellite cell proliferation and differentiation, and Pax7 expression is influenced by glypican-1.

Human Paired Box 7 (PAX7) interaction partners

  1. Data suggest that paired box gene 7 protein (PAX7) target gene repression is a hallmark of facioscapulohumeral muscular dystrophy (FSHD) that should be considered in the investigation of FSHD pathology and therapy.

  2. Transfection experiments showed that the PAX7 splice-site mutation putatively causes nonsense-mediated mRNA decay affecting onlyPAX7 isoform 3.

  3. The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain.

  4. EWSR1 fusion protein is required for PAX7 expression in Ewing sarcoma and identify a candidate EWSR1-FLI1-bound PAX7 enhancer that coincides with both a consensus GGAA repeat-containing binding site and a peak of regulatory H3K27 acetylation.

  5. miR-206 acts as a tumor suppressor in fusion-negative RMS at least partially through downregulation of PAX7.

  6. PAX7 expression is a useful marker of skeletal muscle differentiation in rhabdomyosarcoma, particularly of the embryonal subtype, with specificity for rhabdomyosarcoma and Ewing sarcoma.

  7. NTN1 rs9788972 is identified as a risk locus for nonsyndromic orofacial clefts susceptibility in a northern Chinese population; SNPs in PAX7 were not associated with any increased risk

  8. Our results on Pax7 and MyoD protein expression suggest that proliferation and differentiation of skeletal muscle stem cells are affected in ALS patients, and the myogenic processes cannot overcome the denervation-induced wasting.

  9. these results suggest that sarcoma metastasis can be partially controlled through Pax7/MyoD-dependent activation of miR-182 and provide insight into the role that myogenic transcription factors have in sarcoma progression

  10. RAGE upregulates myogenin which upregulates MyoD and downregulates PAX7, with consequent inhibition of proliferation and stimulation of differentiation.

  11. Pax7 responds to NF-kappaB by impairing the regenerative capacity of myogenic cells in the muscle microenvironment to drive muscle wasting in cancer.

  12. High prevalence of 1p36 microdeletions in B-cell non-Hodgkin lymphomas is associated with PAX7 loss.

  13. Our study replicated previous GWAS findings for markers in VAX1 in the Asian population, and identified rare variants in PAX7 and VAX1 that may contribute to the etiology of CL(P)

  14. In addition, eight genes classified as 'second tier' hits in the original study (PAX7, THADA, COL8A1/FILIP1L, DCAF4L2, GADD45G, NTN1, RBFOX3 and FOXE1) showed evidence of linkage and association in this replication sample.

  15. SUMOylation of Pax7 is essential for neural crest development in chick embryos and for the inhibitory roles of Pax7 in C2C12-muscle differentiation.

  16. PAX3/7-FKHR gene fusions expression was detected in 56% of ARMS tumor samples.

  17. Detection of PAX3/PAX7-FKHR fusion transcripts is a novel tool for Rhabdomyosarcoma diagnosis

  18. PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation.

  19. The presence of PAX3/7-FOXO1 translocation was significantly associated with a higher frequency of metastatic disease.

  20. Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury and disease.

Xenopus laevis Paired Box 7 (PAX7) interaction partners

  1. Our results show that the expression of Pax6 and Pax7 is widely maintained in the adult brain of Xenopus

  2. The Pax3 and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos.

  3. Results show that inhibition of pax7 does not prevent differentiation of satellite cells to myofibres, but it does prevent their maintenance as a stem cell population.

Cow (Bovine) Paired Box 7 (PAX7) interaction partners

  1. The authors detected a novel 10-bp insertion/deletion (indel) polymorphism in the bovine PAX7 promoter and revealed that the indel altered the binding of the transcriptional factor ZNF219.

  2. four novel polymorphisms were identified in the Pax7 gene; the association analysis of genotypes in the single and combined SNP(s) revealed consistent effects on growth traits in NY cattle

Zebrafish Paired Box 7 (PAX7) interaction partners

  1. Cells marked by pax7a only or by both pax7a and pax7b enter the wound rapidly and contribute to muscle wound repair, but each behaves differently.

  2. Pax7 is required for adult skeletal muscle repair.

  3. Pax7 identifies neural crest, chromatophore lineages and pigment stem cells during development.

Profil protéine PAX7

Profil protéine

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Paired Box 7 Protéines (PAX7)

  • paired box 7 (PAX7)
  • paired box protein Pax-7 (PAX7)
  • paired box 7 L homeolog (pax7.L)
  • paired box protein Pax-7 (LOC536229)
  • paired box 7 (Pax7)
  • paired box 7a (pax7a)
  • HUP1 Protéine
  • Pax-7 Protéine
  • pax7 Protéine
  • PAX7B Protéine
  • pax7c Protéine
  • pax7d Protéine
  • pax7e Protéine
  • RGD1564360 Protéine
  • RMS2 Protéine

Protein level used designations for Paired Box 7 Protéines (PAX7)

paired box 7 , paired box gene 7 , transcription factor pax-7 , PAX7 transcriptional factor , paired box homeotic gene 7 , paired box protein Pax-7 , paired domain gene 7 , myogenic specification paired-box transcription factor Pax7 , paired box transcription factor PAX7 , paired box homeotic gene 7a , paired box homeotic gene 7c , paired box homeotic gene 7d , paired box homeotic gene 7e

GENE ID SPECIES
456574 Pan troglodytes
494466 Sus scrofa
100322892 Meleagris gallopavo
100346989 Oryctolagus cuniculus
5081 Homo sapiens
496378 Xenopus laevis
395942 Gallus gallus
487408 Canis lupus familiaris
536229 Bos taurus
500574 Rattus norvegicus
18509 Mus musculus
30587 Danio rerio
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