anti-Peptidyl Arginine Deiminase, Type II (PADI2) Anticorps

PADI2 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. De plus, nous expédions Peptidyl Arginine Deiminase, Type II Kits (16) et Peptidyl Arginine Deiminase, Type II Protéines (13) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PADI2 11240 Q9Y2J8
PADI2 18600 Q08642
PADI2 29511 P20717
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Top anti-Peptidyl Arginine Deiminase, Type II Anticorps sur anticorps-enligne.fr

Showing 10 out of 76 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PADI2 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Humain Lapin Inconjugué WB PADI2 Antibody (C-term) (ABIN658290) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the PADI2 antibody detected the PADI2 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué IHC, WB ABIN6272859 at 1/100 staining Mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of BxPC-3 cells, using PADI2 antibody. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.62 KDa) . Dilution: 1:500~1000 Detection limit for recombinant GST tagged PADI2 is approximately 0.3ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: PADI2 Antibody [NBP2-37918] - Staining of human hippocampus shows strong staining in a subset of glial cells. Immunohistochemistry-Paraffin: PADI2 Antibody  - Staining of human hippocampus shows strong staining in a subset of glial cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Rat Cerebrum lysate; Primary Ab: 3µg/ml Rabbit Anti-Human PADI2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg Connectez-vous pour afficher 13 to 16 Days
$350.00
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué WB PADI2 antibody used at 0.5 ug/ml to detect target protein. 50 μg Connectez-vous pour afficher 2 to 3 Days
$473.93
Détails
Humain Lapin Inconjugué WB Western Blot: PADI2 Antibody [NBP1-54958] - Jurkat cell lysate, concentration 0.2-1 ug/ml. Western Blot: PADI2 Antibody [NBP1-54958] - Hela Whole cell lysates, Antibody Dilution: 1.0 ug/ml. 100 μL Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails

anti-Peptidyl Arginine Deiminase, Type II Anticorps mieux référencés

  1. Human Monoclonal PADI2 Primary Antibody pour ELISA, WB - ABIN564891 : Blachère, Parveen, Fak, Frank, Orange: Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen. dans Arthritis research & therapy 2015 (PubMed)

Plus d’anticorps contre Peptidyl Arginine Deiminase, Type II partenaires d’interaction

Human Peptidyl Arginine Deiminase, Type II (PADI2) interaction partners

  1. the mRNA expression of PADI2, PADI4 (Montrer PADI4 Anticorps) and Sp1 (Montrer PSG1 Anticorps) is upregulated in rheumatoid arthritis bone marrow CD34 (Montrer CD34 Anticorps)+ cells independently of the systemic inflammation or treatment regimen.

  2. These data suggest that overexpression of the human PAD2 transgene in the epidermis of transgenic mice increases the malignant conversion rate of benign tumors by promoting an inflammatory microenvironment.

  3. Brain gene expression of PADI2, ZNF385A (Montrer ZNF385A Anticorps), PSD2, and A2ML1 (Montrer A2ML1 Anticorps) and DNA methylation (Montrer HELLS Anticorps) dysregulations are implicated in the alteration of brain tissue properties associated with late-life cognitive decline above and beyond the influence of common neuropathologic conditions.

  4. Peptidyl arginine deiminase 2 (PADI2) is required for activation of androgen receptor (AR (Montrer AR Anticorps)) signaling under androgen-deprived condition.

  5. Data suggest that protein-arginine deiminase 2 (PADI2) suppresses the proliferation of colonic epithelial cells through catalysis of protein citrullination, and that downregulation of PADI2 expression might therefore contribute to colon carcinogenesis.

  6. Downregulation of PADI2 is an early event in the pathogenesis of colorectal cancer associated with poor prognosis and points toward a possible role of citrullination in modulating tumor cells and their microenvironment.

  7. Multiple proteins citrullinated by hypoxia-induced PADs were identified. In addition, the extracellular domain of vascular endothelial growth factor receptor 2 was citrullinated by human PAD2 in vitro. CONCLUSION: Our data may contribute to understanding of pathophysiology of malignant gliomas from the aspects of protein citrullination.

  8. Deimination of myelin basic protein (MBP) by peptidylarginine deiminase (PAD) prevents its binding to the proteasome and decelerates its degradation by the proteasome in mammalian cells. Potential anticancer drug tetrazole analogue of chloramidine 2, at concentrations greater than 1 microM inhibits the enzymatic activity of PAD in vitro.

  9. this study shows that a miR (Montrer MLXIP Anticorps)-4728 downregulates PADI2, a novel rheumatoid arthritis risk gene

  10. We identified the presence of PADI3 (Montrer PADI3 Anticorps) mRNA expression in synovial tissue and PADI2 and PADI4 (Montrer PADI4 Anticorps) mRNA expressions in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

Cow (Bovine) Peptidyl Arginine Deiminase, Type II (PADI2) interaction partners

Mouse (Murine) Peptidyl Arginine Deiminase, Type II (PADI2) interaction partners

  1. PADi2 contributes to TNFalpha (Montrer TNF Anticorps)-induced citrullination and arthritis, but is not required for neutrophil extracellular traps formation

  2. Taken together, our study is the first to indicate the potential role of Padi2 as an angiogenesis-regulating gene. The characterization of Padi2 and other genes in associated pathways may provide new understanding of angiogenesis regulation and novel targets for diagnosis and treatment of a wide variety of angiogenesis-dependent diseases.

  3. GPx7 (Montrer GPX7 Anticorps) is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys (Montrer DNAJC5 Anticorps) mechanism in which GSH and PDI (Montrer PDIA3 Anticorps) are alternative substrates.

  4. Results suggest that PADI2 may function as an important new biomarker for HER2/ERBB2 (Montrer ERBB2 Anticorps)+ tumors and that Cl-amidine represents a new candidate for breast cancer therapy.

  5. Activation of the P2X7 purinergic receptor (P2X7 (Montrer P2RX7 Anticorps)) by the inflammatory danger signal ATP induces PAD2 activity and robust protein citrullination in mast cells.

  6. different subcellular compartmentalization of PADi2 and citrullinated proteins may have different physiological roles in normal and neurodegenerative conditions

  7. PAD2 interacts with IKKgamma (Montrer IKBKG Anticorps) and suppresses NF-kappaB (Montrer NFKB1 Anticorps) activity.

  8. Results suggest that peptidylarginine deiminase 2-catalyzed citrullination is not essential to the development of experimental autoimmune encephalomyelitis.

  9. An increase in citrullinated proteins resulting from increased PAD2 and 4 is an important change in the pathogenesis of multiple sclerosis.

  10. This study suggests that accumulated citrullinated proteins and abnormal activation of PAD2 may function in the pathogenesis of prion (Montrer PRNP Anticorps) diseases and serve as potential therapeutic targets.

Peptidyl Arginine Deiminase, Type II (PADI2) profil antigène

Profil protéine

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Gene names and symbols associated with PADI2

  • peptidyl arginine deiminase 2 (PADI2) anticorps
  • peptidyl arginine deiminase, type II (padi2) anticorps
  • protein-arginine deiminase type-2 (LOC100357368) anticorps
  • peptidyl arginine deiminase, type II S homeolog (padi2.S) anticorps
  • peptidyl arginine deiminase, type II (PADI2) anticorps
  • peptidyl arginine deiminase, type II (Padi2) anticorps
  • peptidyl arginine deiminase 2 (Padi2) anticorps
  • mKIAA0994 anticorps
  • PAD-H19 anticorps
  • PAD2 anticorps
  • PADI2 anticorps
  • Pdi anticorps
  • Pdi2 anticorps

Protein level used designations for PADI2

peptidyl arginine deiminase, type II , protein-arginine deiminase type-2-like , peptidlyarginine deiminase type II , peptidylarginine deiminase II , protein arginine deiminase , protein-arginine deiminase type II , protein-arginine deiminase type-2 , peptidyl arginine deiminase, type 2 , PAD type II , peptidyl arginine deiminase, type II; PAD type II

GENE ID SPECIES
456527 Pan troglodytes
711044 Macaca mulatta
100050025 Equus caballus
100125112 Xenopus (Silurana) tropicalis
100357368 Oryctolagus cuniculus
100437331 Pongo abelii
100473552 Ailuropoda melanoleuca
11240 Homo sapiens
380061 Xenopus laevis
428172 Gallus gallus
617851 Bos taurus
18600 Mus musculus
29511 Rattus norvegicus
487414 Canis lupus familiaris
100621356 Sus scrofa
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