Peroxidasin Homolog (Drosophila) (PXDN) Kits ELISA

Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). De plus, nous expédions PXDN Anticorps (19) et PXDN Protéines (9) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PXDN 7837 Q92626
PXDN 69675 Q3UQ28
PXDN    
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Top PXDN Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 8 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.065 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$810.53
Détails
Souris 23.43 pg/mL 93.75-6000 pg/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
Détails
Rat 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$880.00
Détails

Plus Kits ELISA pour PXDN partenaires d'interaction

Human Peroxidasin Homolog (Drosophila) (PXDN) interaction partners

  1. PXDN knockdown followed by proteomic analysis revealed an increase in oxidative stress, mitochondrial dysfunction and gluconeogenesis pathways.

  2. we conclude that VPO1 is a crucial regulator of cardiac fibrosis after MI by mediating HOCl/Smad2/3 and ERK1/2 signaling pathways, implying a promising therapeutic target in ischemic cardiomyopathy.

  3. VPO1 is upregulated in abdominal aortic aneurysmal tissues compared with healthy control tissues.

  4. PXDN might play a promoter role in the proliferation, invasion and migration of ovarian cancer (OC) cells through regulating the activation of PI3K/Akt pathway. Therefore, PXDN might be regarded as a potential target for OC therapy.

  5. e showed that collagen IV crosslinks remain intact even under strongly hypoxic conditions. Our hypothesis is that during collagen IV network formation PXDN cooperates with a NOX/DUOX-independent H2O2 source that is functional also at very low ambient oxygen levels.

  6. Data indicate that VPO1 plays a critical role in regulating eNOS expression and activity by structural change and de-phosphorylation. VPO1 expression was up-regulated in Ang-treated HUVECs. Knockdown of VPO1 was su ffi cient to attenuate the Ang induced decrease in eNOS expression and activity. Moreover, the e ff ect of VPO1 on eNOS was mainly achieved by HOCl formation.

  7. Results show that PXDN expression decreases with TGF-beta1 treatment in cervical carcinoma cell lines, and is regulated by the EMT master transcription factor Snai1. This implicates PXDN in cancer development and processes that involve EMT.

  8. Data suggest that VPO1 contributes to oxidation and retention of LDL in vessel walls, and formation foam cells, indicating VPO1 as a novel potential mediator of atherosclerosis.

  9. VPO1 plays a critical role in asymmetric dimethylarginine production via H2O2-VPO1-hypochlorous acid pathways, which may contribute to endothelial dysfunction in hypertension.

  10. The kinetic data unravel the substrate specificity and mechanism of halide oxidation of human peroxidasin 1. The heme enzyme is shown to follow the halogenation cycle that is induced by the rapid H2O2-mediated oxidation of the ferric enzyme to the redox intermediate compound I. Chloride cannot act as a two-electron donor of compound I, whereas thiocyanate, iodide, and bromide efficiently restore the ferric state.

  11. PC processing of Pxdn is a key regulatory step that contributes to its function and, therefore, supports BM integrity and homeostasis.

  12. PXDN expression is significantly upregulated in human masticatory mucosa during wound healing

  13. The catalytic domain of peroxidasin and its immunoglobulin (Ig) domains are required for efficient sulfilimine bond formation.

  14. Novel mutations in PXDN cause microphthalmia and anterior segment dysgenesis

  15. Despite sequence homology at the active site and biophysical properties similar to human peroxidases, the catalytic efficiency of bromide oxidation (kcat/KM(app)) of full-length hsPxd01 is rather low but increased upon truncation.

  16. Peroxidasin is essential for eye development in the mouse.

  17. MiR-4782-3p inhibited cell proliferation in NSCLC by targeting USP14, ZEB2 and XIAP.

  18. studies demonstrate the enzymatic properties and substrate specificity of VPO1 are similar to MPO; however, significantly lower catalytic rate constants of VPO1 relative to MPO suggest the possibility of other physiologic roles for this peroxidase

  19. VPO1 is likely to participate in host defense, with bactericidal activity mediated through the generation of HOCl.

  20. Results from this study indicate that the 2p25.3 duplication disrupting PXDN and MYT1L is a potential autism-causing variant in the pedigree reported here and should receive further consideration as a candidate for autism

Mouse (Murine) Peroxidasin Homolog (Drosophila) (PXDN) interaction partners

  1. Peroxidasin contributes to renal fibrosis in the murine unilateral ureteral obstruction model.

  2. we conclude that VPO1 is a crucial regulator of cardiac fibrosis after MI by mediating HOCl/Smad2/3 and ERK1/2 signaling pathways, implying a promising therapeutic target in ischemic cardiomyopathy.

  3. Vpo1 is upregulated in elastase-induced mouse abdominal aortic aneurysmal tissues compared with healthy control tissues.

  4. Data suggest that VPO1 contributes to oxidation and retention of LDL in vessel walls, and formation foam cells, indicating VPO1 as a novel potential mediator of atherosclerosis.

  5. Embryo implantation triggers dynamic spatiotemporal expression of the basement membrane toolkit (Col4a1, GPBP, Lamc1, peroxidasin) during uterine reprogramming.

  6. Cdkn1b exert its effects via the inhibition of proliferation and is mediated by miR-24 and targeted by the transcription factors FOXO4 and AP4 in the peroxidasin (Pxdn) mutation-induced eye disorders, such as glaucoma.

PXDN profil antigène

Antigen Summary

Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999

Gene names and symbols associated with PXDN

  • peroxidasin (PXDN) anticorps
  • peroxidasin (Pxdn) anticorps
  • 2310075M15Rik anticorps
  • C85409 anticorps
  • D2S448 anticorps
  • D2S448E anticorps
  • E330004E07 anticorps
  • MG50 anticorps
  • mKIAA0230 anticorps
  • PRG2 anticorps
  • PXN anticorps
  • VPO anticorps
  • VPO1 anticorps

Protein level used designations for PXDN

melanoma-associated antigen MG50 , p53-responsive gene 2 protein , peroxidasin homolog , vascular peroxidase 1

GENE ID SPECIES
7837 Homo sapiens
69675 Mus musculus
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