anti-Peroxiredoxin 6 (PRDX6) Anticorps

The protein encoded by PRDX6 is a member of the thiol-specific antioxidant protein family. De plus, nous expédions Peroxiredoxin 6 Protéines (31) et Peroxiredoxin 6 Kits (26) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PRDX6 9588 P30041
PRDX6 11758 O08709
PRDX6 94167 O35244
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Top anti-Peroxiredoxin 6 Anticorps sur anticorps-enligne.fr

Showing 10 out of 197 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-PRDX6 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human Muscle 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PRDX6 Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate PRDX6 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Host:  Rat  Target Name:  PRDX6  Sample Tissue:  Rat Liver  Antibody Dilution:  1ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- Peroxiredoxin 6 Picoband antibody, Western blotting All lanes: Anti Peroxiredoxin 6  at 0.5ug/ml Lane 1: Mouse Liver Tissue Lysate at 50ug Lane 2: 293T Whole Cell Lysate at 40ug Predicted bind size: 25KD Observed bind size: 25KD IHC(P): Human Mammary Cancer Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB PRDX6 Antibody (Center) (ABIN650765) western blot analysis in 293 cell line lysates (35 µg/lane).This demonstrates the PRDX6 antibody detected the PRDX6 protein (arrow). PRDX6 Antibody (Center) (ABIN650765) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of PRDX6 Antibody (C-term) (ABIN389471) in CEM cell line lysates (35 µg/lane). PRDX6 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of PRDX6 (arrow) using rabbit polyclonal PRDX6 Antibody (C-term) (ABIN389471). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PRDX6 gene (Lane 2) . 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-PRDX6 / Peroxiredoxin 6 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this pr ... 50 μg Connectez-vous pour afficher 11 to 14 Days
$727.83
Détails
Humain Souris Inconjugué ELISA, WB PRDX6 monoclonal antibody (M01), clone S1. Western Blot analysis of PRDX6 expression in MCF-7. PRDX6 monoclonal antibody (M01), clone 3A10-2A11. Western Blot analysis of PRDX6 expression in human liver. 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails

anti-Peroxiredoxin 6 Anticorps mieux référencés

  1. Human Monoclonal Peroxiredoxin 6 Primary Antibody pour ELISA, WB - ABIN564140 : Jia, Veiseth-Kent, Grove, Kuziora, Aass, Hildrum, Hollung: Peroxiredoxin-6--a potential protein marker for meat tenderness in bovine longissimus thoracis muscle. dans Journal of animal science 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal Peroxiredoxin 6 Primary Antibody pour IP, ELISA - ABIN532621 : Rhee, Kang, Chang, Jeong, Kim: Peroxiredoxin, a novel family of peroxidases. dans IUBMB life 2002 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal Peroxiredoxin 6 Primary Antibody pour IF, IP - ABIN532556 : Wood, Schröder, Robin Harris, Poole: Structure, mechanism and regulation of peroxiredoxins. dans Trends in biochemical sciences 2003 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal Peroxiredoxin 6 Primary Antibody pour IHC, IHC (p) - ABIN4344944 : Dammeyer, Arnér: Human Protein Atlas of redox systems - what can be learnt? dans Biochimica et biophysica acta 2010 (PubMed)

  5. Human Polyclonal Peroxiredoxin 6 Primary Antibody pour WB - ABIN4344942 : Hossain, De Souza, Bagul, MacPhee, Kessaris, Morsy: HSP70, Peroxiredoxin-3 and -6 are upregulated during renal warm ischaemia in a donation after circulatory death model. dans Journal of proteomics 2014 (PubMed)

Plus d’anticorps contre Peroxiredoxin 6 partenaires d’interaction

Human Peroxiredoxin 6 (PRDX6) interaction partners

  1. we examined the therapeutic efficacy of the Ginkgolic acid (GA), a Sumoylation antagonist, to disrupt aberrant Sumoylation signaling in human and mouse lens epithelial cells (LECs) ...our study revealed an unprecedented role for GA in LECs and provided new mechanistic insights into the use of GA in rescuing LECs from aging/oxidative stress-evoked dysregulation of Sp1/Prdx6 protective molecules

  2. These findings demonstrated that PRDX6 expression plays a characteristic growth-promoting role in Colorectal Cancer metastasis.

  3. These findings implicate miR-371-3p as a suppressor of PRDX6 and suggest that co-targeting of peroxiredoxin 6 or modulating miR-371-3p expression together with targeted cancer therapies may delay or prevent acquired drug resistance.

  4. The present data suggest that PS2 mutations suppress lung tumor development by inhibiting the iPLA2 activity of PRDX6 via a gamma-secretase cleavage mechanism and may explain the inverse relationship between lung cancer and Alzheimer's disease incidence.

  5. The increased HDL and plasma levels of PRDX6 in AAA patients support the potential of PRDX6 as a new biomarker of AAA.

  6. These observations demonstrated that the expression and localization of NPM affected the homeostatic balance of oxidative stress in tumor cells via PRDX6 protein. The regulation axis of NPM/PRDX/ROS may provide a novel therapeutic target for cancer treatment.

  7. the transition-state substrate analogue inhibitor of Prdx6 phospholipase A2 activity (MJ-33) was shown to suppress Nox1 activity, suggesting Nox1 activity is regulated by the phospholipase activity of Prdx6. Finally, wild type Prdx6, but not lipase or peroxidase mutant forms, supports Nox1-mediated cell migration in the HCT-116 colon epithelial cell model of wound closure

  8. The constitutive elevations of Prdx6 and NF-kappaB during Clonorchis sinensis infection may be associated with more severe persistent hepatobiliary abnormalities mediated by clonorchiasis.

  9. Peroxidase activity was markedly reduced by mutation at either of the Leu sites and was essentially abolished by the double mutation, while PLA2 activity was unaffected. Decreased peroxidase activity following mutation of the interfacial leucines presumably is mediated via impaired heterodimerization of Prdx6 with piGST that is required for reduction and re-activation of the oxidized enzyme.

  10. PRX6 protein is associated with fetal esophageal development and cancer differentiation.

  11. Mutational analysis of functional sites showed that both peroxidase and PLA2 active sites were necessary for mutant Prdx6 function, and that Prdx6 phosphorylation (at T177 residue) was essential for optimum PLA2 activity.Mutant Prdx6 at its Sumo1 sites escapes and abates this adverse process by maintaining its integrity and gaining function

  12. PRDX6 inhibited the carcinogenesis of hepatocellular carcinoma, and the calcium-independent phospholipase A2 activity of PRDX6 promoted cancer cell death induced by TNF-alpha.

  13. the data demonstrate that Prdx6 interrupts the formation of TRAF6-ECSIT complex induced by TLR4 stimulation, leading to suppression of bactericidal activity because of inhibited mROS production in mitochondria and the inhibition of NF-kappaB activation in the cytoplasm.

  14. Thus far only the crystal structure of Prx in the oxidized state has been reported. In this study, we present the crystal structures of human Prx6 in the reduced (SH) and the sulfinic acid (SO2H) forms.

  15. Peroxiredoxin 6 has a role in the repair of peroxidized cell membranes and cell signaling [review]

  16. PRDX6-anion exchanger 1 interaction contributes to the maintenance of anion exchanger 1 during cellular stress such as during metabolic acidosis.

  17. Prdx6 is a complete enzyme comprising both PLA2and LPCAT activities

  18. Our study provides new insight into the initial regulatory mechanisms of mitophagy and reveals the protective role of PRDX6 in the clearance of damaged mitochondria.

  19. Thr can substitute for Ser for the enzymatic activities of Prdx6 but not for its targeting to LB. These results confirm an important role for LB Prdx6 in the degradation and remodeling of lung surfactant phosphatidylcholine.

  20. Prdx6 and its PLA2 activity have a protective role in donors after brain death livers.

Mouse (Murine) Peroxiredoxin 6 (PRDX6) interaction partners

  1. we examined the therapeutic efficacy of the Ginkgolic acid (GA), a Sumoylation antagonist, to disrupt aberrant Sumoylation signaling in human and mouse lens epithelial cells (LECs) ...our study revealed an unprecedented role for GA in LECs and provided new mechanistic insights into the use of GA in rescuing LECs from aging/oxidative stress-evoked dysregulation of Sp1/Prdx6 protective molecules

  2. Data (including data from studies in transgenic rats and knockout mice) suggest that Nfe2l2 and Prdx6 are involved in biosynthesis of palmitic acid ester of 9-hydroxystearic acid in white adipose tissue (WAT); these proteins appear to be play roles in defense against oxidative stress in WAT. (Nfe2l2 = nuclear factor erythroid 2-like 2 nuclear factor; Prdx6 = peroxiredoxin-6)

  3. Our data indicate that a lack of the antioxidant enzyme PRDX6 protects against the development of acute and chronic experimental colitis and is associated with increased expression and function of other antioxidant enzymes

  4. The constitutive elevations of Prdx6 and NF-kappaB during Clonorchis sinensis infection may be associated with more severe persistent hepatobiliary abnormalities mediated by clonorchiasis.

  5. Detailed analysis of the redox-active cysteine in one protein in the nerve of old mice that is key to redox signalling (Peroxiredoxin 6, Cys 47) showed a minor increase in reversible oxidation that would be compatible with a change in its redox signalling function

  6. The results suggest that PRDX1 contributes to host defenses against M. tuberculosis PRDX1 positively regulates IL-12 production by inducing c-Rel and activating p38 MAPK, and it positively regulates NO production by suppressing Arg1 expression in macrophages infected with M. tuberculosis.

  7. This study indicated that Prdx6 decreased LPS-induced Muc5ac increase and played important roles in mucin hypersecretion after LPS exposure.

  8. PRDX6 inhibited the carcinogenesis of hepatocellular carcinoma, and the calcium-independent phospholipase A2 activity of PRDX6 promoted cancer cell death induced by TNF-alpha.

  9. Studies in knockout and knock-in mice showed that the phospholipase A2 activity of peroxiredoxin 6 activates NOX2 in cultured pulmonary endothelial cells and alveolar macrophages, clarifying the metabolism of lysophosphatidyl chold to lysophosphatidic acid.

  10. Prdx6 knockout males are more vulnerable to oxidative stress than WT males, resulting in impairment of sperm quality and ability to fertilize the oocyte, compatible with the subfertility phenotype observed in these knockout mice.

  11. Thr can substitute for Ser for the enzymatic activities of Prdx6 but not for its targeting to LB. These results confirm an important role for LB Prdx6 in the degradation and remodeling of lung surfactant phosphatidylcholine.

  12. AP-3-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 and PRDX6 in vitro and in vivo

  13. Prdx6 plays a critical role in the repair of peroxidized phospholipids in cell membranes and the recovery of lung cells from peroxidative stress; the peroxidase and PLA(2) activity each contribute to the recovery process.

  14. The ventral signal observed from E13.5 to E18.5 colocalized with motor neuron markers Isl1/2 and FoxP1 and the strong ventral signal colocalizing with Isl1/2 was observed in all rostrocaudal segments of the spinal cord.

  15. PRDX6 has a role in controlling multiple sclerosis by suppressing inflammation and blood brain barrier disruption

  16. PRDX6 has an important role in dopaminergic neurodegeneration of Parkinson's disease.

  17. Our findings suggest that overexpression of peroxiredoxin 6 might promote development of rheumatoid arthritis through NF-kappaB and AP-1 activity via the JNK pathway.

  18. AA (arachidonic acid) as a crucial effector of PRDX6-dependent proliferation and inducer of Src family kinase activation.

  19. PRDX6 promotes lung tumor development via its mediated and CCL5-associated activation of the JAK2/STAT3 pathway.

  20. Data show that adduction of peroxiredoxin-6 sensitizes male C57BL/6 mice to toxicity by acetaminophen.

Cow (Bovine) Peroxiredoxin 6 (PRDX6) interaction partners

  1. study demonstrated involvement of cytosolic and calcium-independent phospholipase A(2) and the contribution of cyclooxygenase-2 products in E. coli invasion of brain microvascular endothelial cells

  2. dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by iPLA2.

  3. PRDX6 upregulation in cumulus-oocyte complexes during in vitro maturation is mutually regulated by both cell types.

Xenopus laevis Peroxiredoxin 6 (PRDX6) interaction partners

  1. Gene expressionof Prx6 increased during development, especially at stages 33-43 during formation of the lungs.

Pig (Porcine) Peroxiredoxin 6 (PRDX6) interaction partners

  1. The expression of porcine Prdx6 gene is up-regulated by C/EBPbeta and CREB.

  2. The SNP of PRDX6 gene was significantly associated with the intramuscular fat and water moisture.

Peroxiredoxin 6 (PRDX6) profil antigène

Profil protéine

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell\; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Gene names and symbols associated with anti-Peroxiredoxin 6 (PRDX6) Anticorps

  • peroxiredoxin 6 (PRDX6) anticorps
  • peroxiredoxin 6 (Prdx6) anticorps
  • peroxiredoxin 6 (prdx6) anticorps
  • peroxiredoxin 6 S homeolog (prdx6.S) anticorps
  • peroxiredoxin 6 L homeolog (prdx6.L) anticorps
  • 1-Cys anticorps
  • 1-cysPrx anticorps
  • 9430088D19Rik anticorps
  • AA690119 anticorps
  • aiPLA2 anticorps
  • aop2 anticorps
  • Aop2-rs3 anticorps
  • Brp-12 anticorps
  • CC26 anticorps
  • CP-3 anticorps
  • GPx anticorps
  • Ltw-4 anticorps
  • Ltw4 anticorps
  • Lvtw-4 anticorps
  • mKIAA0106 anticorps
  • NSGP anticorps
  • NSGPx anticorps
  • ORF06 anticorps
  • p29 anticorps
  • PHGPX anticorps
  • Prdx5 anticorps
  • prdx6 anticorps
  • Prdx6-rs3 anticorps
  • PRX anticorps
  • prx-6 anticorps
  • prx6 anticorps
  • zgc:73360 anticorps

Protein level used designations for anti-Peroxiredoxin 6 (PRDX6) Anticorps

1-Cys PRX , 1-Cys peroxiredoxin , 24 kDa protein , acidic calcium-independent phospholipase A2 , antioxidant protein 2 , liver 2D page spot 40 , non-selenium glutathione peroxidase , peroxiredoxin-6 , red blood cells page spot 12 , 1-Cys Prx , anti-oxidant protein 2, related sequence 3 , peroxiredoxin 5, related sequence 3 , peroxiredoxin 6, related sequence 3 , NSGPx , aiPLA2 , thiol-specific antioxidant protein , PHGPx , anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) , calcium-independent phospholipase A2 , ciliary body glutathione peroxidase , peroxiredoxin 6 , non-selenium glutathione phospholipid hydroperoxide peroxidase

GENE ID SPECIES
9588 Homo sapiens
11758 Mus musculus
94167 Rattus norvegicus
282438 Bos taurus
393778 Danio rerio
394706 Xenopus (Silurana) tropicalis
398641 Xenopus laevis
399434 Xenopus laevis
429062 Gallus gallus
496787 Xenopus (Silurana) tropicalis
100304983 Ictalurus punctatus
399538 Sus scrofa
100173342 Pongo abelii
101842872 Mesocricetus auratus
100731397 Cavia porcellus
480069 Canis lupus familiaris
101112748 Ovis aries
101691344 Mustela putorius furo
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