Phosphate Cytidylyltransferase 2, Ethanolamine Protéines (PCYT2)

PCYT2 encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. De plus, nous expédions PCYT2 Anticorps (45) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PCYT2 5833 Q99447
PCYT2 68671 Q922E4
PCYT2 89841 O88637
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Top PCYT2 Protéines sur anticorps-enligne.fr

Showing 7 out of 9 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$547.80
Détails
Escherichia coli (E. coli) Humain His tag 50 μg Connectez-vous pour afficher 15 to 19 Days
$953.85
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,072.67
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,120.33
Détails

PCYT2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) partenaires d'interaction

Human Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) interaction partners

  1. differences in phosphorylation between Pcyt2 isoforms

  2. Pcyt2 expression is responsive to tumor nutritional micro-environment, up-regulated in response to metabolic stress under conditions of serum deprivation.

  3. The Pcyt2 promoter is driven by a functional CAAT box (-90/-73) and by negative (-385/-255) and positive regulatory elements (-255/-153) in the upstream regions.

  4. EGR1 (Montrer EGR1 Protéines) is an important transcriptional stimulator of the human PCYT2 and that conditions that modify EGR1 (Montrer EGR1 Protéines) also affect the function of ECT and consequently PE synthesis

Mouse (Murine) Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) interaction partners

  1. we conclude that NF-Y and YY1 (Montrer YY1 Protéines) are important for the basal transcription of Pcyt2 and that NF-Y is involved in the inhibitory effects of 25-HC on Pcyt2 transcription.

  2. The data identify Pcyt2 and membrane Phosphatidylethanolamine biogenesis as important determinants of gender-specific differences in cardiac lipids and heart function.

  3. differences in phosphorylation between Pcyt2 isoforms

  4. hypertriglyceridemia that accompanies Pcyt2 deficiency is the result of multiple metabolic adaptations

  5. data unambiguously establish that the TAG accumulation present in Pcyt2-deficient hepatocytes is a direct consequence of Pcyt2 gene deficiency and reduced functioning of the de novo Kennedy pathway

  6. single Pcyt2 allele in heterozygotes can maintain phospholipid homeostasis

  7. PE phospholipids, Pcyt2 deficiency generates compensatory changes in triglyceride and energy substrate metabolism, resulting in a progressive development of liver steatosis, hypertriglyceridemia, obesity, and insulin (Montrer INS Protéines) resistance

  8. Regulation of the mouse CTP (Montrer PCYT1A Protéines): phosphoethanolamine cytidylyltransferase gene Pcyt2 during myogenesis

  9. study of the importance of the CDP (Montrer CUX1 Protéines)-ethanolamine pathway in controlling the molecular species composition of phosphatidylethanolamine via Phosphoethanolamine cytidylyltransferase knock-out

Profil protéine PCYT2

Profil protéine

This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PCYT2

  • ethanolamine-phosphate cytidylyltransferase (Tc00.1047053511727.120)
  • ethanolamine-phosphate cytidylyltransferase (Tb11.01.5730)
  • ethanolamine-phosphate cytidylyltransferase (LINJ_32_0940)
  • ethanolamine-phosphate cytidylyltransferase (LOC5566800)
  • putative ethanolamine-phosphate cytidylyltransferase (LMJF_32_0890)
  • ethanolamine-phosphate cytidylyltransferase (EDI_013070)
  • ethanolamine-phosphate cytidylyltransferase (EDI_204270)
  • ethanolamine-phosphate cytidylyltransferase (CpipJ_CPIJ009320)
  • ethanolamine-phosphate cytidylyltransferase (Bm1_01855)
  • Ethanolamine-phosphate cytidylyltransferase (pcy2)
  • phosphate cytidylyltransferase 2, ethanolamine (PCYT2)
  • phosphate cytidylyltransferase 2, ethanolamine (Pcyt2)
  • phosphate cytidylyltransferase 2, ethanolamine L homeolog (pcyt2.L)
  • 1110033E03Rik Protéine
  • ET Protéine

Protein level used designations for PCYT2

ethanolamine-phosphate cytidylyltransferase , putative ethanolamine-phosphate cytidylyltransferase , Ethanolamine-phosphate cytidylyltransferase , CTP:phosphoethanolamine cytidylyltransferase , phosphorylethanolamine transferase , CTP:phopshoethanolamine cytidylyltransferase

GENE ID SPECIES
3551699 Trypanosoma cruzi strain CL Brener
3665178 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5071833 Leishmania infantum JPCM5
5566800 Aedes aegypti
5656202 Leishmania major strain Friedlin
5880432 Entamoeba dispar SAW760
5886247 Entamoeba dispar SAW760
6042098 Culex quinquefasciatus
6095325 Brugia malayi
100380284 Salmo salar
5833 Homo sapiens
68671 Mus musculus
444649 Xenopus laevis
510274 Bos taurus
89841 Rattus norvegicus
607608 Canis lupus familiaris
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