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Displays magnesium-independent phosphatidate phosphatase activity in vitro. De plus, nous expédions Phosphatidic Acid Phosphatase Type 2 Domain Containing 1B Protéines (3) et et beaucoup plus de produits pour cette protéine.
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genetic variants at loci -1053 and +64 of the HTPAP promoter affect the expression of HTPAP, which might be a novel determinant and target for HCC prognosis
PPAPDC1B and WHSC1L1 played a major role in regulating the survival of breast cancer, pancreatic adenocarcinoma and small-cell lung cancer-derived cell lines.
Findings identify an HTPAP genotype and associated gene expression pattern that favors metastasis progression and that could be used to predict tumor metastasis and prognosis in HCC patients.
HTPAP-1 may be the transcript of HTPAP to exhibit a suppressive role on hepatocellular cancer(HCC) metastasis, and can be a prognostic marker for HCC.
HTPAP is a novel metastatic suppressor gene for hepatocellular carcinoma
DPPL1 and DPPL2 represent a novel type of mammalian phosphatidate phosphatase.
microarray experiments on PPAPDC1B knockdown indicated this gene interfered with cell signaling pathways, including Janus-activated kinase-signal transducer and activator of transcription, mitogen-activated protein kinase, and protein kinase C pathways
Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol (By similarity).
phosphatidic acid phosphatase type 2 domain containing 1B
, HTPAP protein
, diacylglycerol pyrophosphate like 1
, phosphatidate phosphatase PPAPDC1B
, phosphatidic acid phosphatase type 2 domain-containing protein 1B
, phosphatidic acid phosphatase type 2 domain containing 1