anti-Phosphogluconate Dehydrogenase (PGD) Anticorps

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. De plus, nous expédions PGD Protéines (19) et PGD Kits (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PGD 5226 P52209
PGD 110208 Q9DCD0
PGD 100360180 P85968;
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Top anti-PGD Anticorps sur anticorps-enligne.fr

Showing 10 out of 103 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PGD Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell PGD is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB WB Image PGD antibody [N1N3] detects PGD protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with PGD antibody [N1N3] , diluted at 1:1000. IHC-P Image PGD antibody [N1N3] detects PGD protein at cytoplasm on A549 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded A549 xenograft. PGD antibody [N1N3] , dilution: 1:500. 100 μL 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Disponible
$363.46
Détails
Humain Souris Inconjugué IF, IHC, IHC (p), WB Anti-PGD antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μL 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of PGD expression in A549 (A), Raji (B), mouse lung (C), mouse spleen (D), rat kidney (E) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB ABIN6274785 staining A549 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis of extracts from A549 cells, using PGD antibody. 100 μL 11 to 12 Days
$390.77
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis in 293,MCF-7 cell line lysates (35ug/lane).This demonstrates the detected PGD protein (arrow). Western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the detected PGD protein (arrow). 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using PGD antibody. 100 μL 11 to 13 Days
$366.77
Détails
Humain Souris Inconjugué WB Western Blot analysis of PGD expression in transfected 293T cell line by PGD MaxPab polyclonal antibody.Lane 1: PGD transfected lysate(53.13 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Détails

anti-PGD Anticorps mieux référencés

  1. Human Polyclonal PGD Primary Antibody pour ICC, IF - ABIN441587 : Elf, Lin, Xia, Pan, Shan, Wu, Lonial, Gaddh, Arellano, Khoury, Khuri, Lee, Boggon, Fan, Chen: Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. dans Oncogene 2016 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre PGD partenaires d’interaction

Human Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. 6-phosphogluconate dehydrogenase (6PGD) is aberrantly upregulated and activated in cervical cancer cells and patient tissues compared to normal counterparts. 6PGD inhibition decreases growth and migration, and enhances chemosensitivity in cervical cancer. Inhibition of 6PGD activates AMP-activated protein kinase and decreases rhoA GTP-binding protein and rac1 GTP-binding protein activities.

  2. identified that 6-phosphogluconate dehydrogenase (6PGD) is critically involved in the development of anaplastic thyroid cancer (ATC) resistance to doxorubicin. 6PGD inhibition disrupts metabolic reprogramming in doxorubicin-resistant ATC cells.

  3. Studies indicate link between the 6-phosphogluconate dehydrogenase, oxidative pentose phosphate pathway (PPP) and lipogenesis through Ru-5-P-dependent inhibition of serine/threonine protein kinase LKB1-AMPK signalling.

  4. copy number gain of the PGD gene was consistently identified in cervical cancers but not in the normal tissues

  5. Results show that 6PGD activity is upregulated with increased lysine acetylation in primary leukemia cells from human patients, providing mechanistic insights into 6PGD upregulation in cancer cells.

  6. Expression of 6PGD positively correlates with advancing stage of lung carcinoma. Knockdown of 6PGD by shRNA potently inhibits c-Met tyrosine phosphorylation.

  7. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  8. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

  9. Data suggest that the affinity of Nox2 for NADPH is increased in the presence of 6PGDH on cell stimulation.

  10. Hsa-miR-132 and -212 were negatively correlated with PGD in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

Mouse (Murine) Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  2. Taken together, these data suggest that ADD1/SREBP1c is a key transcription factor for 6PGDH gene expression and would coordinate glucose metabolism and lipogenesis for energy homeostasis.

PGD profil antigène

Profil protéine

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.

Gene names and symbols associated with PGD

  • phosphogluconate dehydrogenase (PGD) anticorps
  • Phosphogluconate dehydrogenase (Pgd) anticorps
  • phosphogluconate dehydrogenase (Pgd) anticorps
  • phosphogluconate dehydrogenase L homeolog (pgd.L) anticorps
  • phosphogluconate dehydrogenase (pgd) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (GND1a|GND1b) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (Thal_1580) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (GY4MC1_3101) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (Odosp_2189) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (Marky_1024) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (gnd) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating-like (LOC101451876) anticorps
  • 6-pgd anticorps
  • 6-PGDH anticorps
  • 6Pgd anticorps
  • 6pgdh anticorps
  • 0610042A05Rik anticorps
  • A7 anticorps
  • AU019875 anticorps
  • C78335 anticorps
  • Cc2-27 anticorps
  • CG3724 anticorps
  • Dmel\\CG3724 anticorps
  • EG:87B1.4 anticorps
  • fi03d03 anticorps
  • GND1b anticorps
  • l(1)2Dc anticorps
  • l(1)2De anticorps
  • l(1)A7 anticorps
  • l(1)G0385 anticorps
  • l(1)N1 anticorps
  • l(1)N3[90] anticorps
  • l(1)Pgd anticorps
  • l(1)Pgd-A anticorps
  • l35 anticorps
  • N1 anticorps
  • Pdg anticorps
  • Pgd anticorps
  • wu:fi03d03 anticorps
  • zgc:55585 anticorps
  • zgc:111848 anticorps

Protein level used designations for PGD

6-phosphogluconate dehydrogenase, decarboxylating , 6-phosphogluconate , 6-phosphogluconate dehydrogenase , CG3724-PA , CG3724-PB , NADP-6 phosphogluconate dehydrogenase , Pgd-PA , Pgd-PB , dehydrogenase , phosphogluconate dehydrogenase , 6-phosphogluconate dehydrogenase (decarboxylating) , 6-phosphogluconate dehydrogenase, decarboxylating-like

GENE ID SPECIES
5226 Homo sapiens
31185 Drosophila melanogaster
110208 Mus musculus
398848 Xenopus laevis
406762 Danio rerio
419450 Gallus gallus
443541 Ovis aries
514939 Bos taurus
5722476 Chlamydomonas reinhardtii
8815110 Thermocrinis albus DSM 14484
9929981 Geobacillus sp. Y4.1MC1
10253936 Odoribacter splanchnicus DSM 220712
10433922 Marinithermus hydrothermalis DSM 14884
10448388 Chlamydophila pecorum E58
100534626 Taeniopygia guttata
100598383 Nomascus leucogenys
397546 Sus scrofa
101451876 Ceratitis capitata
100360180 Rattus norvegicus
101788565 Cavia porcellus
101866917 Macaca fascicularis
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