Phosphogluconate Dehydrogenase (PGD) Kits ELISA

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. De plus, nous expédions PGD Anticorps (102) et PGD Protéines (19) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PGD 5226 P52209
PGD 110208 Q9DCD0
PGD 100360180 P85968;
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Showing 4 out of 9 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.2 ng/mL 0.78-50 ng/mL Typical standard curve 96 Tests 13 to 16 Days
$1,026.67
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Rat
  96 Tests 11 to 18 Days
$618.29
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Souris
  96 Tests 15 to 18 Days
$875.60
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Porc
  96 Tests 15 to 18 Days
$1,029.60
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Plus Kits ELISA pour PGD partenaires d'interaction

Human Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. 6-phosphogluconate dehydrogenase (6PGD) is aberrantly upregulated and activated in cervical cancer cells and patient tissues compared to normal counterparts. 6PGD inhibition decreases growth and migration, and enhances chemosensitivity in cervical cancer. Inhibition of 6PGD activates AMP-activated protein kinase and decreases rhoA GTP-binding protein and rac1 GTP-binding protein activities.

  2. identified that 6-phosphogluconate dehydrogenase (6PGD) is critically involved in the development of anaplastic thyroid cancer (ATC) resistance to doxorubicin. 6PGD inhibition disrupts metabolic reprogramming in doxorubicin-resistant ATC cells.

  3. Studies indicate link between the 6-phosphogluconate dehydrogenase, oxidative pentose phosphate pathway (PPP) and lipogenesis through Ru-5-P-dependent inhibition of serine/threonine protein kinase LKB1-AMPK signalling.

  4. copy number gain of the PGD gene was consistently identified in cervical cancers but not in the normal tissues

  5. Results show that 6PGD activity is upregulated with increased lysine acetylation in primary leukemia cells from human patients, providing mechanistic insights into 6PGD upregulation in cancer cells.

  6. Expression of 6PGD positively correlates with advancing stage of lung carcinoma. Knockdown of 6PGD by shRNA potently inhibits c-Met tyrosine phosphorylation.

  7. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  8. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

  9. Data suggest that the affinity of Nox2 for NADPH is increased in the presence of 6PGDH on cell stimulation.

  10. Hsa-miR-132 and -212 were negatively correlated with PGD in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

Mouse (Murine) Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  2. Taken together, these data suggest that ADD1/SREBP1c is a key transcription factor for 6PGDH gene expression and would coordinate glucose metabolism and lipogenesis for energy homeostasis.

PGD profil antigène

Antigen Summary

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.

Gene names and symbols associated with PGD

  • phosphogluconate dehydrogenase (PGD) anticorps
  • Phosphogluconate dehydrogenase (Pgd) anticorps
  • phosphogluconate dehydrogenase (Pgd) anticorps
  • phosphogluconate dehydrogenase L homeolog (pgd.L) anticorps
  • phosphogluconate dehydrogenase (pgd) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (GND1a|GND1b) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (Thal_1580) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (GY4MC1_3101) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (Odosp_2189) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (Marky_1024) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating (gnd) anticorps
  • 6-phosphogluconate dehydrogenase, decarboxylating-like (LOC101451876) anticorps
  • 6-pgd anticorps
  • 6-PGDH anticorps
  • 6Pgd anticorps
  • 6pgdh anticorps
  • 0610042A05Rik anticorps
  • A7 anticorps
  • AU019875 anticorps
  • C78335 anticorps
  • Cc2-27 anticorps
  • CG3724 anticorps
  • Dmel\\CG3724 anticorps
  • EG:87B1.4 anticorps
  • fi03d03 anticorps
  • GND1b anticorps
  • l(1)2Dc anticorps
  • l(1)2De anticorps
  • l(1)A7 anticorps
  • l(1)G0385 anticorps
  • l(1)N1 anticorps
  • l(1)N3[90] anticorps
  • l(1)Pgd anticorps
  • l(1)Pgd-A anticorps
  • l35 anticorps
  • N1 anticorps
  • Pdg anticorps
  • Pgd anticorps
  • wu:fi03d03 anticorps
  • zgc:55585 anticorps
  • zgc:111848 anticorps

Protein level used designations for PGD

6-phosphogluconate dehydrogenase, decarboxylating , 6-phosphogluconate , 6-phosphogluconate dehydrogenase , CG3724-PA , CG3724-PB , NADP-6 phosphogluconate dehydrogenase , Pgd-PA , Pgd-PB , dehydrogenase , phosphogluconate dehydrogenase , 6-phosphogluconate dehydrogenase (decarboxylating) , 6-phosphogluconate dehydrogenase, decarboxylating-like

GENE ID SPECIES
5226 Homo sapiens
31185 Drosophila melanogaster
110208 Mus musculus
398848 Xenopus laevis
406762 Danio rerio
419450 Gallus gallus
443541 Ovis aries
514939 Bos taurus
5722476 Chlamydomonas reinhardtii
8815110 Thermocrinis albus DSM 14484
9929981 Geobacillus sp. Y4.1MC1
10253936 Odoribacter splanchnicus DSM 220712
10433922 Marinithermus hydrothermalis DSM 14884
10448388 Chlamydophila pecorum E58
100534626 Taeniopygia guttata
100598383 Nomascus leucogenys
397546 Sus scrofa
101451876 Ceratitis capitata
100360180 Rattus norvegicus
101788565 Cavia porcellus
101866917 Macaca fascicularis
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