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may play a role in phospholipase activation, production of prostaglandins, and regulation of inflammatory response [RGD, Feb 2006].. De plus, nous expédions PLAA Kits (36) et PLAA Protéines (14) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal PLAA Primary Antibody pour IF (p), IHC (p) - ABIN704411
Rosing, Fobker, Kannenberg, Gunia, DellAquila, Kwiecien, Stypmann, Nofer: Everolimus therapy is associated with reduced lipoprotein-associated phospholipase A2 (Lp-Pla2) activity and oxidative stress in heart transplant recipients. dans Atherosclerosis 2013
In both human and mouse, hypomorphic mutations in the ubiquitin adaptor protein PLAA cause an infantile-lethal neurodysfunction syndrome with seizures.
Upon damage, p97 (Montrer EIF4G2 Anticorps) translocates to lysosomes and there cooperates with a distinct set of cofactors including UBXD1 (Montrer UBXN6 Anticorps), PLAA, and the deubiquitinating enzyme YOD1 (Montrer YOD1 Anticorps), which we term ELDR components for Endo-Lysosomal Damage Response.
This study presented that Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy.
This review provides evidence that 1,25-dihydroxy vitamin D3 stimulates PLA2 (Montrer YWHAZ Anticorps) via PLAA and CaMKII (Montrer CAMK2G Anticorps), a process initiated by Pdia3 (Montrer PDIA3 Anticorps)/PLAA interaction, which further triggers CaMKII (Montrer CAMK2G Anticorps)-dependent PLA2 (Montrer YWHAZ Anticorps) activation. [review]
PLAP (Montrer ALP Anticorps) inhibits sPLA2 (Montrer PLA2G2A Anticorps)-triggered release of fatty acids from erythrocyte membranes
identified one stimulatory element, with Sp1 (Montrer PSG1 Anticorps) binding sites, and one inhibitory element, in exon 1 of the plaa gene
Structural basis for ubiquitin recognition by a novel domain from the human phospholipase A2-activating protein
We demonstrate that PLAA is essential for neural function, through dual roles of (1) regulating post-endocytic trafficking of signaling receptors necessary for neural development and (2) directing sorting of synaptic vesicle (SV) components during recycling, essential for synaptic function.
miR (Montrer MLXIP Anticorps)-203 may regulate expression of the novel nociceptive mediator PLAA after incision.
Phospholipase A2 activating protein is required for 1alpha,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3 (Montrer PDIA3 Anticorps)
may play a role in phospholipase activation, production of prostaglandins, and regulation of inflammatory response
phospholipase A-2-activating protein
, phospholipase A2-activating protein
, phospholipase A-2-activating protein-like
, DOA1 homolog
, phospholipase A2 activating protein