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The protein encoded by PLTP is one of at least two lipid transfer proteins found in human plasma. De plus, nous expédions PLTP Kits (39) et PLTP Protéines (10) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal PLTP Primary Antibody pour ICC, IF - ABIN152885
Valenta, Ogier, Bradshaw, Black, Bonnet, Lagrost, Curtiss, Desrumaux: Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression. dans Arteriosclerosis, thrombosis, and vascular biology 2006
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Polyclonal PLTP Primary Antibody pour WB - ABIN4369769
Desrumaux, Mak, Boisvert, Masson, Stupack, Jauhiainen, Ehnholm, Curtiss: Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells. dans Journal of lipid research 2003
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Human Monoclonal PLTP Primary Antibody pour IHC (p), ELISA - ABIN562287
Derbali, Bossé, Côté, Pibarot, Audet, Pépin, Arsenault, Couture, Després, Mathieu: Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via Toll-like receptor 2. dans The American journal of pathology 2010
identification and characterization of CaM-binding domain of non-specific lipid transfer proteins
PLTP activity did not affect this metric. Thus, deviations in PLTP activity from the wild-type level reduce HDL (Montrer HSD11B1 Anticorps) mass and ex vivo cholesterol efflux capacity, but not the rate of macrophage cholesterol efflux to plasma or in vivo mRCT.
serum CETP (Montrer CETP Anticorps) and PLTP activity in patients diagnosed with hypothyroidism, was examined.
PLTP may regulate cigarette smoke extract-induced IL-8 expression via the ERK1/2 signaling pathway in human pulmonary epithelial cells
LPL (Montrer LCP1 Anticorps) and PLTP appear to be novel glioma-associated proteins and play a role in the progression of human glioma
association of PON-1 (Montrer PON1 Anticorps) activity with PLTP activity was lost in analysis which included large HDL (Montrer HSD11B1 Anticorps) particles
a novel association between PLTPa and PON1 (Montrer PON1 Anticorps) activity
The domain of apolipoprotein E4 required for PLTP activation resides within its amino-terminal 1-185 region.
Elevated baseline plasma levels of PLTP are associated with an increased risk of long-term all-cause mortality in patients with diabetes and known or suspected coronary disease.
This review summarizes the recent progresses made in the PLTP research field and focuses on the complexity of the implication of PLTP in obesity, insulin (Montrer INS Anticorps) resistance and type 2 diabetes mellitus. [review]
Elevated plasma PLTP activity may predict an increased risk of T2DM in men
this work reports a physiological role for PLTP in the polarization of CD4 (Montrer CD4 Anticorps)(+) T cells toward the pro-inflammatory Th1 (Montrer HAND1 Anticorps) phenotype.
these findings elucidated that PLTP repressed LPS (Montrer TLR4 Anticorps) induced inflammation due to extracellular LPS (Montrer TLR4 Anticorps) binding capability, and the protective effects were not related to HDL (Montrer HSD11B1 Anticorps) pool size in mice.
Data presented a novel model to link phospholipid metabolism to APP (Montrer APP Anticorps) processing and also suggested that PLTP played an important role in Abeta (Montrer APP Anticorps) metabolism and would be useful to further elucidate functions of PLTP in Alzheimer's disease susceptibility.
In hepatocytes, initial recruitment of phospholipid (PL) by apoB (Montrer APOB Anticorps):1000 leading to the formation of the PL-rich apoB (Montrer APOB Anticorps)-containing initiation complex is mediated to a large extent by PLTP.
PLTP plays an important role in modulating the stability of atherosclerotic plaques. The receptor-interacting protein 3 (Montrer RIPK3 Anticorps)- reactive oxygen species signal pathway could be involved in this PLTP-mediated process.
Adipocyte PLTP plays a small but significant role in plasma PLTP activity and promotes cholesterol efflux from adipose tissues.
PLTP exerts significant effects on apoA-I (Montrer APOA1 Anticorps) lipidation and nascent HDL (Montrer HSD11B1 Anticorps) biogenesis in hepatocytes by promoting ATP-binding cassette transporter A1 (Montrer ABCA1 Anticorps)-mediated lipid efflux and the remodeling of nascent HDL (Montrer HSD11B1 Anticorps) particles.
Plasma Sphingosine-1-phosphate contents were decreased by 60.1 % in PLTP knockout mice (PLTP-/-, N = 5) compared with their wild type littermates (WT, N = 5) (151.70 +/- 38.59 vs. 379.32 +/- 59.90 nmol/l, P<0.01).
Therefore we concluded that PLTP deficiency impaired cognition and aggravated AD by enhancing the generation of Abeta (Montrer APP Anticorps) in the cortex of old mice.
Cerebrovascular oxidative stress increased in PLTP deficient mice, including increased levels of reactive oxygen species (ROS) and lipid peroxidation marker 4-hydroxy-2-nonenal (HNE) and reduced superoxide dismutase (SOD) activity.
PLTP is actively involved in lipid transfer, cholesterol efflux, HDL (Montrer HSD11B1 Anticorps) genesis, and remodeling at the blood-brain barrier.
Results suggest that phospholipid transfer protein (PLTP) polymorphisms might be an important genetic influence on economic traits in Hanwoo (Korean cattle).
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.
phospholipid transfer protein
, BPI fold containing family E
, lipid transfer protein II
, plasma phospholipid transfer protein
, PLTP-like protein