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Plxna2 encodes a member of the plexin-A family of semaphorin co-receptors. De plus, nous expédions Plexin A2 Kits (16) et Plexin A2 Protéines (5) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 49 products:
Dog (Canine) Polyclonal Plxna2 Primary Antibody pour WB - ABIN2783972
Budel, Shim, Feng, Zhao, Hisama, Strittmatter: No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios. dans Schizophrenia research 2008
Show all 2 Pubmed References
Human Polyclonal Plxna2 Primary Antibody pour CyTOF, FACS - ABIN4900258
Plein, Calmont, Fantin, Denti, Anderson, Scambler, Ruhrberg: Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation. dans The Journal of clinical investigation 2015
used Sema6A (Montrer SEMA6A Anticorps)-deficient and PlxnA2-deficient zebrafish embryos in a microarray analysis to identify genes that were differentially expressed when this signaling pathway was disrupted.
Sema6a (Montrer SEMA6A Anticorps) and Plxna2 have roles in promoting eye vesicle cohesion through mediating spatially regulated repulsion within the developing zebrafish eye
Data indicate that plexin A1 (Montrer PLXNA1 Anticorps)-4 (PLXNA1 (Montrer PLXNA1 Anticorps)-4) mediation of neuroanatomical traits can be detected using in vivo neuroimaging techniques.
although plexin-A4 (Montrer PLXNA4 Anticorps) overexpression restored Sema3A (Montrer SEMA3A Anticorps) signaling in plexin-A1 (Montrer PLXNA1 Anticorps)-silenced cells, it failed to restore Sema3B (Montrer SEMA3B Anticorps) signaling in plexin-A2-silenced cells.
PLXNA2 upregulation contributes to TMPRSS2 (Montrer TMPRSS2 Anticorps):ERG (Montrer ERG Anticorps)-mediated enhancements of PC3c cell migration and invasion.
PLXNA2 has been identified as a new rare copy number variations gene for tetralogy of Fallot.
results of our study reveal that PlxnA2 has a pro-osteogenic function by modulating BMP2 (Montrer BMP2 Anticorps) signaling
PLXNA2 polymorphisms show association with ankylosing spondylitis.
in vitro analysis of PLXNA2 revealed that the gene has higher expression in more aggressive breast cancer cell types.
An association is identified between variants in the PLXNA2 gene and schizophrenia in two collections of schizophrenia cases and controls. High-density SNP mapping showed that the region of association spans approximately 60 kb of the PLXNA2 gene.
results suggest that PLXNA2 may not play a major role in the development of schizophrenia in our Japanese sample
PLXNA2 confers a varying genetic risk for schizophrenia among different populations.
These findings implicate Semaphorin-6A (Montrer SEMA6A Anticorps) - Plexin-A2/Plexin-A4 (Montrer PLXNA4 Anticorps) interactions in dorsal lateral geniculate nucleus axon guidance and in the spatiotemporal organization of guidepost cell populations in the mammalian subpallium.
describe procedures for protein production and purification that we utilized in the crystallographic study of the mouse Plexin A2 (mPlxnA2) extracellular fragment, including the sema (Montrer SEMA3B Anticorps) domain
Using time-lapse videomicroscopy we provide evidence that Sema6A (Montrer SEMA6A Anticorps)/PlexinA2 signaling participates to interkinetic nuclear migration of retinal progenitor cell
Plexin A2 is expressed in both On and Off starburst amacrine cell.
crystal structures of cognate complexes of the semaphorin-binding regions of plexins B1 and A2 with semaphorin ectodomains (human PLXNB1 (Montrer PLXNB1 Anticorps)(1-2)-SEMA4D (Montrer SEMA4D Anticorps)(ecto (Montrer TRIM33 Anticorps)) and murine PlxnA2(1-4)-Sema6A (Montrer SEMA6A Anticorps)(ecto (Montrer TRIM33 Anticorps))), plus unliganded structures of PlxnA2(1-4) and Sema6A (Montrer SEMA6A Anticorps)(ecto (Montrer TRIM33 Anticorps))
crystal structures of the semaphorin 6A (Sema6A (Montrer SEMA6A Anticorps)) receptor-binding fragment and the plexin A2 (PlxnA2) ligand-binding fragment in both their pre-signalling (that is, before binding) and signalling (after complex formation) states
This study demonstrated that Sema6B (Montrer SEMA6B Anticorps), another class 6 transmembrane semaphorin, is expressed in CA3 (Montrer CA3 Anticorps) and repels mossy fibers in a PlxnA4 (Montrer PLXNA4 Anticorps)-dependent manner in vitro.
In plexin-A2-deficient mice many granule cells remained in the molecular layer; mouse chimera studies further suggested that plexin-A2 acts in a cell-autonomous manner.
mutations in GATA6 (Montrer GATA6 Anticorps) are genetic causes of congenital heart diseases involving outflow tract defects, as a result of the disruption of the direct regulation of semaphorin 3C (Montrer SEMA3C Anticorps)-plexin A2 signaling
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.
, plexin A2
, plexin 2
, semaphorin receptor OCT
, transmembrane protein OCT
, plex 2