anti-Plexin D1 (PLXND1) Anticorps

Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. De plus, nous expédions Plexin D1 Protéines (4) et Plexin D1 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PLXND1 23129 Q9Y4D7
PLXND1 67784 Q3UH93
PLXND1 312652  
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Top anti-Plexin D1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 63 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, FACS, IF ABIN185358 Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing membrane/cytoplasmic staining. The nuclear stain i ABIN185358 Flow cytometric analysis of paraformaldehyde fixed K562 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml). IgG control: Unimmunized goat IgG (black line) fol 100 μg 6 to 7 Days
$429.84
Détails
Humain Lapin Inconjugué ICC, IF, WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using Plexin D1, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué EIA 0.4 mL 6 to 8 Days
$484.00
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA   100 μg 11 to 14 Days
$610.50
Détails
Humain Chèvre PE FACS   100 Tests 11 to 14 Days
$1,013.83
Détails
Humain Lapin Inconjugué ICC, WB   100 μL 11 to 14 Days
$537.17
Détails
Humain Chèvre Inconjugué FACS, ELISA, WB   100 μg 11 to 14 Days
$1,167.83
Détails
Boeuf (Vache) Chèvre Inconjugué EIA, IHC (p), WB   0.1 mg 6 to 8 Days
$445.50
Détails
Humain Chèvre Biotin IHC, ELISA, WB   100 μL 16 Days
$760.57
Détails
Humain Chèvre PE IHC, ELISA, WB   100 μL 16 Days
$760.57
Détails

anti-Plexin D1 Anticorps mieux référencés

  1. Human Polyclonal PLXND1 Primary Antibody pour CyTOF, FACS - ABIN4900364 : Lu, Evans, Hirano, Liu: Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity. dans Proceedings of the National Academy of Sciences of the United States of America 2014 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal PLXND1 Primary Antibody pour ELISA, IHC - ABIN268775 : Parikh, Eisner, Venugopalan, Yang, Lam, Bhattacharya: Proteomic analyses of corneal tissue subjected to alkali exposure. dans Investigative ophthalmology & visual science 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal PLXND1 Primary Antibody pour ELISA - ABIN547405 : Gu, Yoshida, Livet, Reimert, Mann, Merte, Henderson, Jessell, Kolodkin, Ginty: Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. dans Science (New York, N.Y.) 2005 (PubMed)

  4. Human Polyclonal PLXND1 Primary Antibody pour ICC, IF - ABIN443493 : Jurcak, Rucki, Muth, Thompson, Sharma, Ding, Zhu, Eshleman, Anders, Jaffee, Fujiwara, Zheng: Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice. dans Gastroenterology 2019 (PubMed)

Plus d’anticorps contre Plexin D1 partenaires d’interaction

Human Plexin D1 (PLXND1) interaction partners

  1. The role of Plexin D1 in tumor development and progression is thereby garnering research interest for its potential as a biomarker and as a therapeutic target.

  2. Anti-plexin D1 antibodies are a novel biomarker for immunotherapy-responsive neuropathic pain.

  3. the receptor Plexin-D1 contains a sorting motif that interacts with the adaptor protein GIPC1 to facilitate transport to recycling endosomes.

  4. SNPs associated with type 2 diabetes and obesity may also increase the risk of developing gestational diabetes mellitus (GDM) in the Chinese population. Among these SNPs, we report for the first time that rs945508 in ARHGEF11, rs10804591 in PLXND1 and rs10245353 in NFE2L3 were associated with GDM.

  5. Authors found that the PlexinD1 cleavage product binds to actin rods, pathological aggregate-like structures which had so far been described for age-related neurodegenerative diseases. Data suggest a novel disease mechanism for SMA involving formation of actin rods as a molecular sink for a cleaved PlexinD1 fragment leading to dysregulation of receptor signaling.

  6. Measuring electrical impedance allows real-time monitoring of changes in endothelial cell morphology and adhesion induced by SEMA3E via plexin D1

  7. Plexin D1 plays a role in collagen contraction in human lung fibroblasts.

  8. Findings suggest that Plexin-D1/class III semaphorin (Sema3E) axis is triggered in systemic sclerosis (SSc) endothelium.

  9. finding that PLXND1 and REV3L mutations are responsible for a proportion of MBS patients suggests that de novo mutations in other genes might account for other MBS patients

  10. The data indicate that Plexin-D1 operates in a cell context-specific fashion, mediating different synaptogenic outcomes depending upon neuron type.

  11. Plxnd1 is a novel regulator of VAT growth, body fat distribution, and insulin sensitivity in both zebrafish and humans

  12. The identification and characterization of SH3BP1 as a novel downstream effector of Sema3E-PlexinD1 provides an explanation for how extracellular signals are translated into cytoskeletal changes and unique cell behavior.

  13. It is therefore suggested that SEMA3C signaling, propagated through the heterodimer receptor plexin-D1/neuropilin, is important for truncus arteriosus septation

  14. A critical role of Sema3E/Plexin D1 interaction in tumor resistance to apoptosis.

  15. Strong expression of plexD1 was detected in endothelial cells of cervical cancer samples, yet no expression was seen in endothelial cells of normal cervical tissues, which suggests a potential role of PlexD1 in cervical cancer-associated angiogenesis

  16. analysis of Sema3E/plexin-D1 mediated epithelial-to-mesenchymal transition in ovarian endometrioid cancer

  17. a novel phospholipid-regulated antiangiogenic signaling pathway whereby Sema3E activates Arf6 through Plexin-D1 and consequently controls integrin-mediated endothelial cell attachment to the extracellular matrix and migration.

  18. Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

  19. Semaphorin 3E-Plexin D1 signaling in cancer cells is crucially implicated in their metastatic behavior and may therefore be a promising target for strategies aimed at blocking tumor metastasis.

  20. Sema3E acts on plexin D1 to initiate a two-pronged mechanism involving R-Ras inactivation and Arf6 stimulation, which affect the status of activation of integrins and their intracellular trafficking, respectively.

Mouse (Murine) Plexin D1 (PLXND1) interaction partners

  1. Results describe new roles of Sema3E/PlexinD1 signaling during development and in adult hippocampal formation and provide evidence for an implication of Sema3E/PlexinD1 in the layer-specific development of the entorhino-hippocampal connection.

  2. Authors found that the PlexinD1 cleavage product binds to actin rods, pathological aggregate-like structures which had so far been described for age-related neurodegenerative diseases. Data suggest a novel disease mechanism for SMA involving formation of actin rods as a molecular sink for a cleaved PlexinD1 fragment leading to dysregulation of receptor signaling.

  3. GIPC1 forms a domain-swapped dimer in an autoinhibited conformation that hinders binding of both PlexinD1 and myosin VI. PlexinD1 binding to GIPC1 releases the autoinhibition, promoting its interaction with myosin VI. GIPCs and myosin VI interact through two distinct interfaces and form an open-ended alternating array.

  4. Sema3G induces cell collapse in an Nrp2/PlexinD1-dependent manner.

  5. Our results demonstrate that sema3e/plexin D1 modulates IS formation and Ag-scanning activities of thymocytes within thymic tissues.

  6. Sema3E/PlexinD1 signaling controls the motogenic potential of Cajal-Retzius (CR) cells in vitro and in vivo. Absence of Sema3E/PlexinD1 signalling increased the migratory properties of CR cells.

  7. Sema3E-PlexinD1 signaling is involved in the development of CNV. Stimulation of the pathway has therapeutic potential for CNV.

  8. Proprioceptive sensory afferents that express PlexinD1 avoid forming monosynaptic connections with neurons in Sema3E(+) motor pools yet are able to form direct connections with neurons in Sema3E(off) motor pools.

  9. beta1 integrin adhesion is controlled by the plexinD1-sema3E axis in mice

  10. Data an association between Plexin-B2 and Plexin-D1 with the negative regulation of IL-12/IL-23p40 in DCs.

  11. This study demonstrated that Sema3E and Plexin-D1 specify the degree of glutamatergic connectivity between a specific source and target in the complex circuitry of the basal ganglia.

  12. a novel role of Sema3E-Plexin-D1 function in modulating angiogenesis via a VEGF-induced feedback mechanism

  13. Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

  14. Plexin-D1 is expressed by B lymphocytes. PlxnD1 deficient B cells fail to participate efficiently in the GC reaction. And, recall immune responses are attenuated in the absence of plexin-D1, leading to defective Ab production.

  15. Sema3E acts on plexin D1 to initiate a two-pronged mechanism involving R-Ras inactivation and Arf6 stimulation, which affect the status of activation of integrins and their intracellular trafficking, respectively.

  16. Interruption of Plexin D1 pathway in mice results in congenital heart disease and vascular patterning defects due to endothelial defects.

  17. signaling by semaphorin 3E and its receptor plexin-D1 controls endothelial cell positioning and the patterning of the developing vasculature in the mouse

  18. Plexin D1 mRNA was preferentially expressed in layers II-V in the mouse cortices.

  19. Data show that PlexinD1 is involved in the patterning of axial skeletogenesis.

  20. Our data reveal a "gating" function of neuropilin-1 in semaphorin3e-plexinD1 signaling during the assembly of forebrain neuronal circuits

Zebrafish Plexin D1 (PLXND1) interaction partners

  1. Sema3d regulates collective endothelial cell migration in zebrafish through two separate mechanisms. Mesenchymal Sema3d guides outgrowth of the common cardinal vein via repulsion and signals through PlexinD1.

  2. Plxnd1 is a novel regulator of VAT growth, body fat distribution, and insulin sensitivity in both zebrafish and humans

  3. Somite expression of known vascular guidance cues, efnb2, sema3a2, and plexinD1 are disrupted, suggesting that the inter-somitic vessel vascular phenotype is due to disruption of these cues.

  4. We show that proper blood vessel pathfinding requires the endothelial receptor PlexinD1 and semaphorin signals, and we identify mutations in plexinD1 in the zebrafish vascular patterning mutant out of bounds

  5. Loss of plxnB2 results in delayed ISV sprouting identical to that seen in sema3e morphants, while loss of plexinD1 in out of bounds (obd) mutants results in precocious ISV sprouting.

Plexin D1 (PLXND1) profil antigène

Profil protéine

Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Mediates anti-angiogenic signaling in response to SEMA3E. Required for normal development of the heart and vasculature.

Gene names and symbols associated with anti-Plexin D1 (PLXND1) Anticorps

  • plexin D1 (PLXND1) anticorps
  • plexin D1 (Plxnd1) anticorps
  • plexin D1 (plxnd1) anticorps
  • plexin-D1 (LOC100409974) anticorps
  • 6230425C21Rik anticorps
  • b2b553Clo anticorps
  • plexd1 anticorps
  • zgc:77379 anticorps

Protein level used designations for anti-Plexin D1 (PLXND1) Anticorps

plexin-D1 , obd , out of bounds , plexin D1 , plexin-D1-like , LOW QUALITY PROTEIN: plexin-D1

GENE ID SPECIES
23129 Homo sapiens
67784 Mus musculus
312652 Rattus norvegicus
402998 Danio rerio
416124 Gallus gallus
460687 Pan troglodytes
476526 Canis lupus familiaris
779491 Xenopus (Silurana) tropicalis
781625 Bos taurus
100409974 Callithrix jacchus
100451917 Pongo abelii
100483438 Ailuropoda melanoleuca
100545536 Meleagris gallopavo
100595621 Nomascus leucogenys
100152254 Sus scrofa
100716223 Cavia porcellus
Fournisseurs de qualité sélectionnés pour anti-Plexin D1 (PLXND1) Anticorps
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