PCBP1 Kits ELISA
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA.
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PCBP1 profil antigène
Profil protéine
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
Gene names and symbols associated with PCBP1
- poly(rC) binding protein 1 (PCBP1) anticorps
- poly(rC) binding protein 1 L homeolog (pcbp1.L) anticorps
- poly(rC)-binding protein 1 (LOC100388387) anticorps
- poly(rC) binding protein 1 (Pcbp1) anticorps
- alphaCP-1 anticorps
- hnRNP-E1 anticorps
- hnRNP-X anticorps
- hnRNP E1 anticorps
- HNRPE1 anticorps
- HNRPX anticorps
- PCBP1 anticorps
- RGD1561319 anticorps
- WBP17 anticorps
- [a]CP-1 anticorps
Protein level used designations for PCBP1
poly(rC) binding protein 1 , poly(rC)-binding protein 1-like , alpha-CP1 , heterogeneous nuclear ribonucleoprotein E1 , heterogenous nuclear ribonucleoprotein E1 , heterogenous nuclear ribonucleoprotein X , nucleic acid-binding protein SUB2.3 , poly(rC)-binding protein 1 , hnRNP-E1 protein , hnRNP E1 , hnRNP-E1
GENE ID | SPECIES |
---|---|
459300 | Pan troglodytes |
100037147 | Xenopus laevis |
100388387 | Callithrix jacchus |
100459720 | Pongo abelii |
5093 | Homo sapiens |
509917 | Bos taurus |
100008848 | Oryctolagus cuniculus |
23983 | Mus musculus |
500242 | Rattus norvegicus |
481417 | Canis lupus familiaris |
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