Profil protéine

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

Gene names and symbols associated with PCBP1

• poly(rC) binding protein 1 (PCBP1) anticorps
• poly(rC) binding protein 1 L homeolog (pcbp1.L) anticorps
• poly(rC)-binding protein 1 (LOC100388387) anticorps
• poly(rC) binding protein 1 (Pcbp1) anticorps

• alphaCP-1 anticorps
• hnRNP-E1 anticorps
• hnRNP-X anticorps
• hnRNP E1 anticorps
• HNRPE1 anticorps
• Afficher tous les alias de synonymes
• HNRPX anticorps
• PCBP1 anticorps
• RGD1561319 anticorps
• WBP17 anticorps
• [a]CP-1 anticorps

Protein level used designations for PCBP1

poly(rC) binding protein 1 , poly(rC)-binding protein 1-like , alpha-CP1 , heterogeneous nuclear ribonucleoprotein E1 , heterogenous nuclear ribonucleoprotein E1 , heterogenous nuclear ribonucleoprotein X , nucleic acid-binding protein SUB2.3 , poly(rC)-binding protein 1 , hnRNP-E1 protein , hnRNP E1 , hnRNP-E1