Poly (ADP-Ribose) Polymerase Family, Member 3 Protéines (PARP3)

The protein encoded by PARP3 belongs to the PARP family. De plus, nous expédions PARP3 Anticorps (105) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PARP3 10039 Q9Y6F1
Souris PARP3 PARP3 235587  
Rat PARP3 PARP3 300985  
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Top PARP3 Protéines sur anticorps-enligne.fr

Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
Baculovirus infected Insect Cells Humain GST tag,His tag 100 μg Connectez-vous pour afficher 14 to 16 Days
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 11 Days
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
Insect cells (Sf21) Humain HA tag,His tag   10 μg Connectez-vous pour afficher 5 to 8 Days
Insect cells (Sf9) Humain Inconjugué   20 μg Connectez-vous pour afficher 11 to 16 Days

PARP3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , , , ,
, , , ,

Plus protéines pour Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) partenaires d'interaction

Zebrafish Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) interaction partners

  1. Parp3 is crucial in the early stages of zebrafish development, possibly by exerting its transcriptional regulatory functions as early as during the specification of the neural plate border

Human Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) interaction partners

  1. Our results indicated this approach with PARP3 inhibitors and vinorelbine is unique and promising for breast cancer patients with metastases. This combination could significantly increase the survival of breast cancer patients with metastases

  2. These data identify PARP3 as a molecular sensor of nicked nucleosomes.

  3. PARP3 controls of TGFbeta-induced epithelial mesenchymal transformation and acquisition of stem-like cell features by stimulation transglutaminase 2/SNAI1 signaling.

  4. Data indicate that PARP3, a DNA damage-activated ADP-ribosyltransferase, can mono-ADP-ribosylate double-stranded DNA ends.

  5. In a process of single-strand DNA repair, PARP3 mono-ADP-ribosylates nucleosomal histone H2B.

  6. we found that PARP3 interacted with FoxM1 to enhance its transcriptional activity and conferred glioblastoma cell radioresistance. Thus, our data suggest that PARP3 could be a therapeutic target to overcome radioresistance in glioblastoma

  7. Identification of ADP-ribosylation sites in PARP3 and the determination of the extent ofpoly(ADP-ribosyl)ated residues in this protein was performed.

  8. MiR-630 reduced apoptosis by downregulating several apoptotic modulators, PARP3, DDIT4, and EP300.

  9. In some cancer cells, repression of PARP3 could be responsible for an increased telomerase activity.

  10. PARP3 likely facilitates the recruitment of Ku80 to double strand breaks to antagonize DNA end resection but facilitate Ku-mediated accurate classical non-homologous end-joining.

  11. PARP3 gene occupancy in the human neuroblastoma cell line SK-N-SH occurs preferentially with developmental genes regulating cell fate specification, tissue patterning, craniofacial development and neurogenesis.

  12. PARP3 is a critical player in the stabilization of the mitotic spindle and in telomere integrity by associating and regulating the mitotic components NuMA and tankyrase 1.

  13. PARP-3 has a role in chromosomal DNA double-strand break repair.

  14. the interaction between PARP-1 and PARP-3 is unrelated to DNA single-strand break repair

  15. PARP-3 is a nuclear protein involved in transcriptional silencing and in the cellular response to DNA damage

Mouse (Murine) Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) interaction partners

  1. these data indicate that Parp3 and Parp1 promote rearrangements with distinct phenotypes.

  2. We show that Poly(ADP)ribose polymerase 3 (Parp3), an enzyme recently implicated in DNA repair, contributes to antibody diversification by negatively regulating class switch recombination without affecting somatic hypermutation.

  3. PARP-3 has a role in chromosomal DNA double-strand break repair.

  4. We cloned and sequenced the cDNAs of the mouse PARP-3 (Adprt3) gene encoding poly(ADP-ribose) polymerase 3 and of the closely linked U3-55k gene coding for the U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein.

Profil protéine PARP3

Profil protéine

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with PARP3

  • seed maturation protein PM38 (PARP3)
  • poly (ADP-ribose) polymerase family, member 3 (parp3)
  • poly(ADP-ribose) polymerase family member 3 (PARP3)
  • poly(ADP-ribose) polymerase family member 3 L homeolog (parp3.L)
  • poly(ADP-ribose) polymerase family member 3 (parp3)
  • poly (ADP-ribose) polymerase family, member 3 (Parp3)
  • A930002C11Rik Protéine
  • ADPRT-3 Protéine
  • Adprt3 Protéine
  • ADPRTL2 Protéine
  • ADPRTL3 Protéine
  • ARTD3 Protéine
  • AW990611 Protéine
  • fj17c06 Protéine
  • IRT1 Protéine
  • pADPRT-3 Protéine
  • PARP-3 Protéine
  • parp3 Protéine
  • PM38 Protéine
  • wu:fj17c06 Protéine
  • zgc:66157 Protéine

Protein level used designations for PARP3

NAD(+) ADP-ribosyltransferase 3 , poly [ADP-ribose] polymerase 3 , poly[ADP-ribose] synthase 3 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3 , poly (ADP-ribose) polymerase family, member 3 , Poly synthetase 3 , poly [ADP-ribose] polymerase 3-like , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3 , ADP-ribosyltransferase diphtheria toxin-like 3 , ADPRT-3 , NAD+ ADP-ribosyltransferase 3 , poly(ADP-ribose) synthetase-3 , poly[ADP-ribose] synthetase 3 , A DP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose polymerase)-like 3 , Poly[ADP-ribose] synthetase-3 , poly (ADP-ribosyl) transferase-like 3

548024 Glycine max
335495 Danio rerio
460409 Pan troglodytes
484745 Canis lupus familiaris
496154 Xenopus laevis
699294 Macaca mulatta
771158 Gallus gallus
100060729 Equus caballus
100145803 Xenopus (Silurana) tropicalis
100194925 Salmo salar
100301771 Oncorhynchus mykiss
100438948 Pongo abelii
100479913 Ailuropoda melanoleuca
100597938 Nomascus leucogenys
100344824 Oryctolagus cuniculus
10039 Homo sapiens
507426 Bos taurus
235587 Mus musculus
300985 Rattus norvegicus
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