Polycomb Group Ring Finger 6 (PCGF6) Kits ELISA

The protein encoded by PCGF6 contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. De plus, nous expédions PCGF6 Anticorps (45) et PCGF6 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PCGF6 84108 Q9BYE7
PCGF6 71041 Q99NA9
PCGF6 309457 Q5XI70
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Top PCGF6 Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 6 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 20 pg/mL 78-5000 pg/mL   96 Tests 2 to 3 Days
$713.90
Détails
Rat
  96 Tests 15 to 18 Days
$1,029.60
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Souris
  96 Tests 15 to 18 Days
$1,029.60
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Plus Kits ELISA pour PCGF6 partenaires d'interaction

Human Polycomb Group Ring Finger 6 (PCGF6) interaction partners

  1. Pcgf6 acts as a master regulator to maintain embryonic stem cell identity.

  2. regulation by cell cycle-dependent phosphorylation

  3. Thus, we did not find evidence for uniquely interacting partner proteins using this approach, but did identify four new lamin A/C interactive partners

  4. Study shows that JARID1d and MBLR occupy human Engrailed 2 gene and regulate its expression and histone H3 lysine 4 methylation levels.

  5. MEL-18 bound to HSF2 inhibits its sumoylation by binding to and inhibiting the activity of UBC9 enzymes in the vicinity of HSF2.

  6. Mel-18 overexpression showed reduced glycogen synthase kinase-3beta phosphorylation, beta-catenin nuclear localization, T-cell factor/lymphoid enhancer factor promoter activity, and cyclin D1 mRNA level

Mouse (Murine) Polycomb Group Ring Finger 6 (PCGF6) interaction partners

  1. Pcgf6 acts as a master regulator to maintain embryonic stem cell identity.

  2. Conditional ablation of Pcgf6 in embryonic stem cells leads to robust de-repression of germ cell-related genes, in turn affecting cell growth and viability.

  3. The results identify two key regulators, PCGF6 and JARID1c that temper dendritic cells (DC) activation and implicate active transcriptional silencing via histone demethylation as a previously unappreciated mechanism for regulating DC activation and quiescence.

  4. Pcgf6 is essential for recruitment of PRC1.6 to chromatin. Our results reveal a previously uncharacterized, H2AK119ub1-independent chromatin assembly associated with PRC1.6 complex

  5. that Pcgf6 is nonredundantly involved in maintaining the pluripotent nature of embryonic stem cells and it functions in induced pluripotent stem reprogramming

  6. regulation by cell cycle-dependent phosphorylation

PCGF6 profil antigène

Antigen Summary

The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with PCGF6

  • polycomb group ring finger 6 (PCGF6) anticorps
  • polycomb group ring finger 6 (pcgf6) anticorps
  • polycomb group ring finger 6 (Pcgf6) anticorps
  • 4933407A11Rik anticorps
  • AI604840 anticorps
  • im:7144322 anticorps
  • MBLR anticorps
  • Rnf134 anticorps
  • si:ch211-67n3.7 anticorps

Protein level used designations for PCGF6

polycomb group ring finger 6 , polycomb group RING finger protein 6 , polycomb group RING finger protein 6-like , Mel18 and Bmi1-like RING finger protein , ring finger protein 134 , Mel18- and Bmi1-like RING finger protein

GENE ID SPECIES
450710 Pan troglodytes
507739 Bos taurus
555238 Danio rerio
609633 Canis lupus familiaris
714508 Macaca mulatta
770712 Gallus gallus
84108 Homo sapiens
71041 Mus musculus
309457 Rattus norvegicus
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