Polyhomeotic Homolog 3 (Drosophila) Protéines (PHC3)

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. De plus, nous expédions Polyhomeotic Homolog 3 (Drosophila) Anticorps (21) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat PHC3 PHC3 310258  
PHC3 80012 Q8NDX5
PHC3 241915 Q8CHP6
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Top Polyhomeotic Homolog 3 (Drosophila) Protéines sur anticorps-enligne.fr

Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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PHC3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Polyhomeotic Homolog 3 (Drosophila) (PHC3) partenaires d'interaction

Human Polyhomeotic Homolog 3 (Drosophila) (PHC3) interaction partners

  1. Data show that polycomb (Montrer CBX2 Protéines)-group proteins BMI1 (Montrer BMI1 Protéines), PHC3, CBX6 (Montrer CBX6 Protéines) and CBX7 (Montrer CBX7 Protéines) expression was significantly increased during imatinib treatment.

  2. PHC3 amplification may emerge as a biomarker in cancer.

  3. SAM (Montrer TTN Protéines) linker controls PHC3 SAM (Montrer TTN Protéines) polymerization

  4. PHC3 is a tumor suppressor in osteosarcoma cells abd its suppression may be caused by modification of polycomb (Montrer CBX2 Protéines) repressive complex 1 in cancer cells.

  5. loss of PHC3 may favor tumorigenesis by potentially disrupting the ability of cells to remain in G(0)

Profil protéine Polyhomeotic Homolog 3 (Drosophila) (PHC3)

Profil protéine

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

Gene names and symbols associated with PHC3

  • polyhomeotic homolog 3 (Phc3)
  • polyhomeotic homolog 3 (PHC3)
  • polyhomeotic-like 3 (Drosophila) (Phc3)
  • E030046K01Rik Protéine
  • Edr3 Protéine
  • Hph3 Protéine

Protein level used designations for PHC3

polyhomeotic-like protein 3 , polyhomeotic like 3 , polyhomeotic homolog 3 (Drosophila) , early development regulator 3 , early development regulatory protein 3 , homolog of polyhomeotic 3 , polyhomeotic 3

GENE ID SPECIES
310258 Rattus norvegicus
460843 Pan troglodytes
100346297 Oryctolagus cuniculus
80012 Homo sapiens
241915 Mus musculus
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