Polymerase (DNA-Directed), delta Interacting Protein 3 Protéines (POLDIP3)

POLDIP3 encodes a protein that interacts with the DNA polymerase delta p50 subunit. De plus, nous expédions POLDIP3 Anticorps (77) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
POLDIP3 84271 Q9BY77
POLDIP3 73826 Q8BG81
Rat POLDIP3 POLDIP3 315170  
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Top POLDIP3 Protéines sur anticorps-enligne.fr

Showing 4 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 11 Days
$888.80
Détails
Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
Détails

POLDIP3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour Polymerase (DNA-Directed), delta Interacting Protein 3 (POLDIP3) partenaires d'interaction

Human Polymerase (DNA-Directed), delta Interacting Protein 3 (POLDIP3) interaction partners

  1. Altered expression of PDIP46 or its mutation may affect Pol delta functions in vivo, and thereby be a nexus for altered genomic stability.

  2. hnRNP-U inhibits TDP-43-mediated alterations in splicing of POLDIP3 mRNA.

  3. PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export.

  4. these findings establish critical and essential roles for SKAR in the regulation of mRNA translation of IFN-sensitive genes and induction of IFN-alpha biological responses.

  5. Alteration of POLDIP3 splicing associated with loss of function of TDP-43 in tissues affected with amyotrophic lateral sclerosis (ALS) .

  6. SKAR is a specific target of S6K1 and regulates cell growth.

  7. This study showed that PDIP46 aka SKAR, a protein possessing one RNA recognition motif (RRM) and being a protein partner of both the p50 subunit of DNA polymerase delta and p70 ribosomal protein S6 kinase 1 (S6K1).

  8. SKAR-mediated recruitment of activated S6K1 to newly processed mRNPs serves as a conduit between mTOR checkpoint signaling and the pioneer round of translation when cells exist in conditions supportive of protein synthesis.

Profil protéine POLDIP3

Profil protéine

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.

Gene names and symbols associated with POLDIP3

  • polymerase (DNA-directed), delta interacting protein 3 S homeolog (poldip3.S)
  • DNA polymerase delta interacting protein 3 (POLDIP3)
  • polymerase (DNA-directed), delta interacting protein 3 (Poldip3)
  • DNA polymerase delta interacting protein 3 (Poldip3)
  • 1110008P04Rik Protéine
  • AA408269 Protéine
  • AL022852 Protéine
  • C77954 Protéine
  • mKIAA1649 Protéine
  • PDIP46 Protéine
  • SKAR Protéine

Protein level used designations for POLDIP3

DNA polymerase delta interacting protein 3 , polymerase delta-interacting protein 3 , 46 kDa DNA polymerase delta interaction protein , RNA-binding protein P46 , S6K1 Aly/REF-like target , polymerase delta interacting protein 46

GENE ID SPECIES
444041 Xenopus laevis
417974 Gallus gallus
84271 Homo sapiens
474480 Canis lupus familiaris
512693 Bos taurus
73826 Mus musculus
315170 Rattus norvegicus
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