anti-Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) Anticorps

is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate.

afficher tous les anticorps Gène GeneID UniProt
Anti-Souris  319801 Q8BZA9
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Top anti-Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) Anticorps sur anticorps-enligne.fr

Showing 10 out of 109 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Anti-C12orf5 / TIGAR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960902 concentration 10 ug/ml. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Chien Lapin Inconjugué IHC, IHC (p), WB Anti-C12orf5 / TIGAR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960901 concentration 10 ug/ml. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$474.10
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$474.10
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Breast (formalin-fixed, paraffin-embedded) stained with C12orf5 antibody ABIN213914 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with C12orf5 antibody ABIN214419 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Souris Lapin Inconjugué WB TIGAR Antibody (N-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TIGAR antibody detected the TIGAR protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué WB Western Blot: TIGAR/C12orf5 Antibody  - Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE gel, diluted at 1:2000. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse intestine labeled with Rabbit Anti TIGAR Polyclonal Antibody, Unconjugated (ABIN671286) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit Anti TIGAR Polyclonal Antibody, Unconjugated (ABIN671286) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$306.90
Détails

anti-Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) Anticorps mieux référencés

  1. Human Polyclonal Primary Antibody pour IHC, ELISA - ABIN1003279 : Corcoran, Huang, Sheikh: The regulation of energy generating metabolic pathways by p53. dans Cancer biology & therapy 2007 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal Primary Antibody pour IHC, ELISA - ABIN1003280 : Bensaad, Tsuruta, Selak, Vidal, Nakano, Bartrons, Gottlieb, Vousden: TIGAR, a p53-inducible regulator of glycolysis and apoptosis. dans Cell 2006 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) partenaires d’interaction

Mouse (Murine) Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) interaction partners

  1. TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis.

  2. Results suggest that TIGAR expression changes during development and its expression level may be correlated with the vulnerability of neurons to ischemic injury.

  3. Although mouse TIGAR expression is clearly induced in the intestines of mice following DNA-damaging stress of ionizing radiation, that was not dependent on p53 (Montrer TP53 Anticorps) or TAp73 (Montrer TP73 Anticorps).

  4. TIGAR protein expression in brain is increased following ischemia reperfusion injury.

  5. Therefore, we conclude that TIGAR knockdown-induced radiosensitization of glioma cells may be dependent on the inhibition of TRX1 (Montrer TXN Anticorps) nuclear translocation.

  6. TIGAR protects ischemic brain injury and preserves mitochodrial function.

  7. TIGAR has roles in efficient intestinal regeneration and tumorigenesis

  8. p53/TIGAR-mediated inhibition of myocyte mitophagy is responsible for impairment of mitochondrial integrity and subsequent apoptosis.

  9. p53 and TIGAR inhibit glycolysis in hypoxic myocytes and that inhibition of glycolysis is closely involved in apoptosis, suggesting that p53 and TIGAR are significant mediators of cellular energy homeostasis and cell death under ischemic stress.

Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) profil antigène

Profil protéine

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.

Gene names and symbols associated with

  • Trp53 induced glycolysis repulatory phosphatase (Tigar) anticorps
  • AA793651 anticorps
  • AI595337 anticorps
  • C79710 anticorps
  • C85509 anticorps
  • Tigar anticorps

Protein level used designations for

TP53-induced glycolysis and apoptosis regulator , fructose-2,6-bisphosphatase TIGAR , probable fructose-2,6-bisphosphatase TIGAR

GENE ID SPECIES
319801 Mus musculus
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