anti-Programmed Cell Death 1 (PDCD1) Anticorps

May have a role in the regulation of spermatogenesis.. De plus, nous expédions PD-1 Protéines (93) et PD-1 Kits (24) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PDCD1 5133 Q15116
PDCD1 301626  
PDCD1 18566 Q02242
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Top anti-PD-1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 653 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué BR, FACS   0.5 mg Connectez-vous pour afficher 6 to 8 Days
$271.98
Détails
Souris Hamster arménien Inconjugué BR, FACS, IP   0.1 mg Connectez-vous pour afficher 6 to 8 Days
$163.12
Détails
Humain Chèvre Inconjugué BR, CyTOF, ELISA (Capture), FACS, IHC, WB Detection of Human PD-1 by Western Blot. Western blot shows lysate of human thymus tissue. PVDF membrane was probed with 2 ug/mL of Goat Anti-Human PD-1 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. PD-1 in Human Lymph Node. PD-1 was detected in immersion fixed paraffin-embedded sections of human lymph node using Goat Anti-Human PD-1 Antigen Affinity-purified Polyclonal Antibody  at 3 ug/mL overnight at 4 ᄚC. Tissue was stained using the Anti-Goat HRP-DAB Cell & 100 μg Connectez-vous pour afficher 8 to 9 Days
$463.45
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN185400 (0.6µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Humain Chèvre Biotin ELISA (Detection), FACS, WB Detection of PD-1 in Human PBMCs treated with PHA by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ug/mL PHA overnight were stained with Goat Anti-Human PD-1 Biotinylated Antigen Affinity-purified Polyclonal Antibody. 50 μg Connectez-vous pour afficher 8 to 9 Days
$451.95
Détails
Humain Lapin Inconjugué WB Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml Lane 1: JURKAT Whole Cell Lysate at 40ug Lane 2: Human Placenta Tissue Lysate at 50ug Predicted bind size: 32KD Observed bind size: 38KD Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml WB: Recombinant Human PD1 Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Souris Chèvre PE FACS Detection of PD-1 in Mouse CD4+ T-Cells by Flow Cytometry. Mouse CD4+ T-cells were stained with Goat Anti-Mouse PD-1 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Connectez-vous pour afficher 8 to 9 Days
$351.90
Détails
Humain Lapin Inconjugué WB Western blot analysis of CD279 expression in THP1 (A), HepG2 (B), mouse liver (C), H9C2 (D) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Souris Inconjugué EIA, WB 0.1 mL Connectez-vous pour afficher 6 to 8 Days
$412.50
Détails
Humain Souris Inconjugué CyTOF, FACS, WB Detection of PD-1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ng/mL PHA for 2 days were stained with Mouse Anti-Human PD-1 Monoclonal Antibody. Detection of Human PD-1 by Western Blot. Western blot shows lysates of HEK293 human embryonic kidney cell line either mock transfected or transfected with human PD-1. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human PD-1 Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Connectez-vous pour afficher 8 to 9 Days
$346.15
Détails

PDCD1 Anticorps par réactivité, application, clonalité et conjugué

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anti-PD-1 Anticorps mieux référencés

  1. Human Polyclonal PD-1 Primary Antibody pour BR, CyTOF - ABIN5012979 : Wan, Nie, Liu, Feng, He, Xu, Zhang, Dong, Zhang: Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis. dans Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 11 Pubmed References

  2. Human Polyclonal PD-1 Primary Antibody pour ELISA (Detection), FACS - ABIN4899871 : Sakthivel, Ramanujam, Wang, Pirskanen, Lefvert: Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. dans Journal of neuroimmunology 2008 (PubMed)
    Show all 9 Pubmed References

  3. Human Monoclonal PD-1 Primary Antibody pour BR, FACS - ABIN2689142 : Bennett, Luxenberg, Ling, Wang, Marquette, Lowe, Khan, Veldman, Jacobs, Valge-Archer, Collins, Carreno: Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. dans Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 8 Pubmed References

  4. Mouse (Murine) Monoclonal PD-1 Primary Antibody pour BR, FACS - ABIN2689141 : Nishimura, Agata, Kawasaki, Sato, Imamura, Minato, Yagita, Nakano, Honjo: Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes. dans International immunology 1997 (PubMed)
    Show all 7 Pubmed References

  5. Human Polyclonal PD-1 Primary Antibody pour IHC, ELISA - ABIN1002980 : Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. dans Human immunology 2004 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal PD-1 Primary Antibody pour IHC, ELISA - ABIN1002981 : Ishida, Agata, Shibahara, Honjo: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. dans The EMBO journal 1992 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal PD-1 Primary Antibody pour ICC, FACS - ABIN438813 : Dorrell, Abraham, Lanxon-Cookson, Canaday, Streeter, Grompe: Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. dans Stem cell research 2009 (PubMed)
    Show all 3 Pubmed References

  8. Mouse (Murine) Polyclonal PD-1 Primary Antibody pour CyTOF, FACS - ABIN4899873 : Kasagi, Kawano, Okazaki, Honjo, Morinobu, Hatachi, Shimatani, Tanaka, Minato, Kumagai: Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. dans Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal PD-1 Primary Antibody pour IF (p), IHC (p) - ABIN735608 : Zhang, Niyazi, Hong, Tuluwengjiang, Zhang, Zhang, Su, Bao: Effect of EBI3 on radiation-induced immunosuppression of cervical cancer HeLa cells by regulating Treg cells through PD-1/PD-L1 pathway. dans Tumour biology 2017 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal PD-1 Primary Antibody pour FACS - ABIN2479653 : Ochonisky, Chosidow, Kuentz, Man, Fraitag, Pelisse, Revuz: Cogan's syndrome. An unusual etiology of urticarial vasculitis. dans Dermatologica 1992 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre PD-1 partenaires d’interaction

Human Programmed Cell Death 1 (PDCD1) interaction partners

  1. These results demonstrate the involvement of sPD (Montrer HOXD13 Anticorps)-1 in the disease course of chronic HBV infection and indicate the potential to apply sPD (Montrer HOXD13 Anticorps)-1 as a biomarker for differentiating IT from other phases and HCC (Montrer FAM126A Anticorps) from other disease conditions in chronic HBV infection.

  2. summarizes the latest research on PD-1 in infectious diseases and discusses its role in acute and chronic viral infection[review]

  3. Our study demonstrates a cross-talk between PARPi and tumor-associated immunosuppression and provides evidence to support the combination of PARPi and PD-L1 (Montrer CD274 Anticorps) or PD-1 immune checkpoint blockade as a potential therapeutic approach to treat breast cancer

  4. Results show that high programmed cell death 1 (PDCD1, PD-1)methylation (mPDCD1) was associated with a significantly shorter overall survival after surgical resection.

  5. Suggest that genetic polymorphisms of PD-1 function as sex-dependent risk factors for development of acute rejection in an Iranian kidney transplant population.

  6. downregulation in PD-1 inhibitory signaling in RA could be attributed to increased serum sPD (Montrer HOXD13 Anticorps)-1 and decreased synovial tissue PD-L1 (Montrer CD274 Anticorps) levels

  7. PD1 polymorphisms are associated with susceptibility to chronic hepatitis B infection in the Chinese population.

  8. PD-1 seems to correlate with disease progression in epitheliotropic T cell dyscrasias ranging from minimal staining in prelymphomatous dyscrasias to significant staining in mycosis fungoides

  9. in some tumor types, PD-L2 (Montrer PDCD1LG2 Anticorps) expression is more closely linked to Th1 (Montrer TH1L Anticorps)/IFNG (Montrer IFNG Anticorps) expression and PD-1 and CD8 (Montrer CD8A Anticorps) signaling than PD-L1 (Montrer CD274 Anticorps)

  10. Although mutational and immunologic differences have been proposed as the primary determinants of heterogeneous response/resistance to targeted therapies and immunotherapies, respectively, differential lesional gene expression profiles may also dictate anti-PD-1 outcomes

Mouse (Murine) Programmed Cell Death 1 (PDCD1) interaction partners

  1. An examination of the mechanisms of immunity behind this long-term protection in PD-1 knockout mice showed a key role for parasite-specific CD8 (Montrer CD8A Anticorps)(+) T cells even when CD4 (Montrer CD4 Anticorps)(+) T cells and B cells responded to re-infection.

  2. To test the in vivo activity of REGN2810, which does not cross-react with murine PD-1, knock-in mice were generated to express a hybrid protein containing the extracellular domain of human PD-1, and transmembrane and intracellular domains of mouse PD-1

  3. The combination of tumor vaccination to induce high avidity tumor specific T cell responses and PD-1 blockade synergises to provide tumor therapy and 85% survival in the aggressive B16 melanoma model.

  4. Blockade of PD-1 with monoclonal antibody may be an effective treatment during the postoperative period for restoring surgery-induced immunosuppression.

  5. Data suggest that genetic or environmental factors that even moderately affect the expression of both PD-1 and FoxP3 (Montrer FOXP3 Anticorps) can cause life-threatening autoimmune diseases by disrupting the T-cell homeostasis.

  6. Data (including data from studies in transgenic/knockout mice) suggest that T-cell expression of Mirn155 is required to limit melanoma growth; miR (Montrer MLXIP Anticorps)-155, Pdcd1, Pdcd1l1 (Montrer CD274 Anticorps), and Ctla4 (Montrer CTLA4 Anticorps) appear to regulate overlapping pathways promoting antitumor immunity. [Mirn155 = microRNA 155; Pdcd1 = programmed cell death 1 protein; Pdcd1l1 (Montrer CD274 Anticorps) = programmed cell death 1 ligand 1 (Montrer CD274 Anticorps) protein; Ctla4 (Montrer CTLA4 Anticorps) = cytotoxic T-lymphocyte-associated protein 4 (Montrer CTLA4 Anticorps)]

  7. PD-1 plays a vital role in brain inflammation via regulation of Fgl-2 (Montrer FGL2 Anticorps) after ICH (Montrer ACE Anticorps), and that manipulation of PD-1 might be a promising therapeutical target in ICH (Montrer ACE Anticorps).

  8. We identified PD-1 to be specifically expressed in PLZF (Montrer ZBTB16 Anticorps)(+) ILCp and revealed that the timing and order of expression of the transcription factors NFIL3 (Montrer NFIL3 Anticorps), ID2, and TCF-1 (Montrer HNF1A Anticorps) was critical. Importantly, induction of ILC (Montrer CCL27 Anticorps) lineage commitment required only transient expression of NFIL3 (Montrer NFIL3 Anticorps) prior to ID2 and TCF-1 (Montrer HNF1A Anticorps) expression.

  9. The identification of the role for PD-1 in regulating B cell-dependent antitumor immunity to Tn antigen highlights an opportunity to develop new therapeutic strategies targeting tumor-associated carbohydrate antigens

  10. These findings suggest that PD-1 pathway blockade may reverse adaptive immune resistance following cyclic dinucleotide treatment, enhancing both local and systemic antitumor immunity.

Rhesus Monkey Programmed Cell Death 1 (PDCD1) interaction partners

  1. Data show that CTLA-4 (Montrer CTLA4 Anticorps)(+)PD-1(-) memory CD4 (Montrer CD4 Anticorps)(+) T cells, which share phenotypic markers with regulatory T cells, were enriched in SIV DNA in blood, lymph nodes (LN), spleen, and gut (Montrer GUSB Anticorps), and contained replication-competent and infectious virus.

  2. Compared to before immunosuppression, PD-1 expression increased at reactivation. Increased T cells before zoster is likely due to virus reactivation.

  3. A PD-1(high) phenotype is associated with accelerated in vivo CD8 (Montrer CD8A Anticorps) T cell turnover in SIV-infections, especially within the SIV-specific CD8 (Montrer CD8A Anticorps) T cell pool.

  4. High levels of PD-1 expression on CD4 (Montrer CD4 Anticorps)(+) T cells in lymph nodes of rhesus macaques can serve as a valuable marker to identify T follicular helper cells.

  5. Data indicate that PD-1 expression is increased as a result of T cell activation during a primary immune response as well as during persistent immune activation in macaques.

  6. PD-1 can serve as a sensitive indicator of persistent, low-level virus replication

PD-1 (PDCD1) profil antigène

Profil protéine

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Gene names and symbols associated with PDCD1

  • programmed cell death 1 (PDCD1) anticorps
  • programmed cell death 1 (Pdcd1) anticorps
  • CD279 anticorps
  • hPD-1 anticorps
  • hPD-l anticorps
  • Ly101 anticorps
  • PD-1 anticorps
  • PD1 anticorps
  • Pdc1 anticorps
  • SLEB2 anticorps

Protein level used designations for PDCD1

programmed cell death protein 1 , protein PD-1 , programmed cell death 1 , programmed death 1 , mPD-1

GENE ID SPECIES
5133 Homo sapiens
301626 Rattus norvegicus
424913 Gallus gallus
613842 Bos taurus
18566 Mus musculus
486213 Canis lupus familiaris
100135775 Macaca mulatta
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