anti-Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) Anticorps

The protein encoded by PCSK7 belongs to the subtilisin-like proprotein convertase family. De plus, nous expédions Proprotein Convertase Subtilisin/kexin Type 7 Protéines (8) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PCSK7 9159 Q16549
PCSK7 18554 Q61139
PCSK7 29606 Q62849
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Top anti-Proprotein Convertase Subtilisin/kexin Type 7 Anticorps sur anticorps-enligne.fr

Showing 10 out of 34 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB PCSK7 Antibody (C-term) (ABIN657966) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the PCSK7 antibody detected the PCSK7 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Souris Inconjugué FACS, IF HEK293T cells transfected with either pCMV6-ENTRY PCSK7 (RC203896) (Red) or empty vector control plasmid (Blue) were immunostained with anti-PCSK7 mouse monoclonal (ABIN2453428, Dilution 1:1,000), and then analyzed by flow cytometry. Anti-PCSK7 mouse monoclonal antibody (ABIN2453428) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PCSK7 (RC203896). 0.1 mL Connectez-vous pour afficher Disponible
$482.90
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Connectez-vous pour afficher 11 to 12 Days
$305.71
Détails
Humain Lapin Inconjugué ELISA, WB PCSK7 antibody western blot analysis in K562 lysate. 0.4 mL Connectez-vous pour afficher 2 to 3 Days
$411.13
Détails
Humain Souris Inconjugué WB Western Blot analysis of PCSK7 expression in transfected 293T cell line by PCSK7 MaxPab polyclonal antibody.<br><br>Lane 1: PCSK7 transfected lysate(65.01 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué ELISA, WB   200 μL Connectez-vous pour afficher 11 to 16 Days
$594.00
Détails
Humain Lapin PE ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails
Humain Lapin FITC ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails
Humain Lapin HRP ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails
Humain Lapin APC ELISA, WB   200 μL Connectez-vous pour afficher 16 Days
$743.29
Détails

PCSK7 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Plus d’anticorps contre Proprotein Convertase Subtilisin/kexin Type 7 partenaires d’interaction

Xenopus laevis Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) interaction partners

  1. SPC7 is required for normal development of the eye and brain, possibly through processing BMPs, though other potential substrates cannot be excluded.

Zebrafish Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) interaction partners

  1. PCSK7 is essential for zebrafish development and regulates the expression and proteolytic cleavage of TGFbeta1a.

Human Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) interaction partners

  1. Our present data suggest that PCSK7 as well as PCSK9 (Montrer PCSK9 Anticorps) may be associated with lipids, especially triglyceride, and may serve as a candidate for a new drug target to treat lipid abnormality syndromes.

  2. PCSK7 rs236918 C allele is a risk factor for cirrhosis development in Italian patients with HFE-Hemochromatosis (Montrer HFE Anticorps).

  3. Furin (Montrer FURIN Anticorps) and PC7 siRNAs induced HIF-1alpha (Montrer HIF1A Anticorps) protein by increasing its translation, resulting in upregulation of VEGF-A (Montrer VEGFA Anticorps).

  4. The data suggest that PCSK7 genotypes may interact with dietary CHO (Montrer COL11A1 Anticorps) intake on changes in insulin (Montrer INS Anticorps) sensitivity in the white Americans.

  5. Results demonstrate that PCSK7 variation is a strong host risk factor of liver cirrhosis in hereditary hemochromatosis (Montrer HFE Anticorps) patients homozygous for HFE (Montrer HFE Anticorps) C282Y.

  6. overexpression of PCs, furin (Montrer FURIN Anticorps) and PC5 (Montrer PCSK5 Anticorps), but not PC7, which are all expressed in SMC (Montrer DYM Anticorps), increase PKGI (Montrer PRKG1 Anticorps) cleavage in a dose-dependent manner

  7. Among the PC family members, only furin (Montrer FURIN Anticorps) activates hepcidin (Montrer HAMP Anticorps) in hepatocytes, and uniquely the full-length membrane-bound PC7 can directly shed hTfR1 by cleavage at Arg100

  8. PCSK7 is involved in sTfR (Montrer TFRC Anticorps) generation and iron homeostasis.

  9. Proprotein convertase PC7 enhances the activation of the EGF receptor (Montrer EGFR Anticorps) pathway through processing of the EGF (Montrer EGF Anticorps) precursor.

  10. PC7 is distinct from other proprotein convertases in its zymogen activation, subcellular localization, and trafficking.

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) interaction partners

  1. PC7 has a critical role in normal processing of cholecystokinin (Montrer CCK Anticorps) in mouse brain

  2. PC7 and the related proteases Furin (Montrer FURIN Anticorps) and Pace4 (Montrer PCSK6 Anticorps) regulate E-cadherin (Montrer CDH1 Anticorps) function during blastocyst formation.

  3. Data show that BDNF (Montrer BDNF Anticorps) and PC7 mRNAs are colocalized in hippocampus and amygdala and that mature BDNF (Montrer BDNF Anticorps) protein levels are reduced in these brain areas in proprotein convertase PC7 knockout mice.

  4. overexpression of PCs, furin (Montrer FURIN Anticorps) and PC5 (Montrer PCSK5 Anticorps), but not PC7, which are all expressed in SMC (Montrer DYM Anticorps), increase PKGI (Montrer PRKG1 Anticorps) cleavage in a dose-dependent manner

  5. Proprotein convertase PC7 enhances the activation of the EGF receptor (Montrer EGFR Anticorps) pathway through processing of the EGF (Montrer EGF Anticorps) precursor.

  6. in binding VEGFR-2 (Montrer KDR Anticorps), furin (Montrer FURIN Anticorps) and PC5 (Montrer PCSK5 Anticorps) promote cleavage of N-and C-terminal VEGF-D (Montrer Figf Anticorps) propeptides, whereas PC7 promotes cleavage of the C-terminal propeptide only

Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) profil antigène

Profil protéine

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.

Gene names and symbols associated with PCSK7

  • proprotein convertase subtilisin/kexin type 7 (PCSK7) anticorps
  • proprotein convertase subtilisin/kexin type 7 L homeolog (pcsk7.L) anticorps
  • proprotein convertase subtilisin/kexin type 7 (pcsk7) anticorps
  • proprotein convertase subtilisin/kexin type 7 (Pcsk7) anticorps
  • AA959856 anticorps
  • LPC anticorps
  • MGC115258 anticorps
  • pc7 anticorps
  • PC8 anticorps
  • PCSK7 anticorps
  • SPC7 anticorps
  • wu:fj05c03 anticorps
  • zgc:158336 anticorps

Protein level used designations for PCSK7

proprotein convertase PC7 , proprotein convertase subtilisin/kexin type 7 , fj05c03 , proprotein convertase subtilisin/kexin type 7-like , hPC8 , lymphoma proprotein convertase , prohormone convertase 7 , prohormone convertase PC7 , proprotein convertase 7 , proprotein convertase 8 , subtilisin/kexin-like protease PC7 , subtilisin-like proprotein convertase 7 , rPC7

GENE ID SPECIES
395455 Gallus gallus
451571 Pan troglodytes
479423 Canis lupus familiaris
515398 Bos taurus
697567 Macaca mulatta
735091 Xenopus laevis
100009656 Danio rerio
100062727 Equus caballus
100388007 Callithrix jacchus
100461035 Pongo abelii
100544206 Meleagris gallopavo
9159 Homo sapiens
18554 Mus musculus
29606 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) Anticorps
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