anti-Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Anticorps

PTGIS encodes a member of the cytochrome P450 superfamily of enzymes. De plus, nous expédions Prostaglandin I2 (Prostacyclin) Synthase Kits (38) et Prostaglandin I2 (Prostacyclin) Synthase Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PTGIS 5740 Q16647
PTGIS 19223 O35074
PTGIS 25527 Q62969
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Top anti-Prostaglandin I2 (Prostacyclin) Synthase Anticorps sur anticorps-enligne.fr

Showing 10 out of 70 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PTGIS Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human brain 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of CYP8A1 Antibody (C-term) (ABIN652421) in CEM cell line lysates (35 µg/lane). CYP8A1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with PAX3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-CYP8A1 Antibody (N-term) (ABIN392532) in mouse lung tissue lysates (35 µg/lane). CYP8A1(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP8A1 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué EIA, WB Formalin-fixed and paraffin-embedded human prostate carcinoma reacted withPTGIS Antibody (C-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of PTGIS Antibody (C-term) Cat.-No AP17980PU-N in CEM cell line lysates (35ug/lane). CYP8A1 (arrow) was detected using the purified Pab. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Humain Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Rat Prostate lysate; Primary Ab: 2µg/ml Rabbit Anti-Human PTGIS Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg Connectez-vous pour afficher 13 to 16 Days
$316.00
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis in K562 cell line lysates (35ug/lane). PTGIR Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué IP, WB Immunoprecipitation of PTGIS transfected lysate using anti-PTGIS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PTGIS purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of PTGIS expression in transfected 293T cell line by PTGIS MaxPab polyclonal antibody.<br><br>Lane 1: PTGIS transfected lysate(57.10 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μL Connectez-vous pour afficher 11 to 12 Days
$425.71
Détails

PTGIS Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Prostaglandin I2 (Prostacyclin) Synthase Anticorps mieux référencés

  1. Human Polyclonal PTGIS Primary Antibody pour ELISA, WB - ABIN562513 : Gurgul-Convey, Hanzelka, Lenzen: Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion. dans Endocrinology 2012 (PubMed)

Plus d’anticorps contre Prostaglandin I2 (Prostacyclin) Synthase partenaires d’interaction

Human Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) interaction partners

  1. In examining the tumor suppressor PTGIS as a potential biomarker for treatment with either 5-Aza-dC or TSA (Montrer PRDX2 Anticorps), 5-Aza-dC effectively stabilized cell cycling, restricted genetic instability and derepressed PTGIS expression

  2. Based on the predicted crystal structure of CYP8A1( *)5 using the Molecular Operating Environment platform, the distance from CYP8A1 Cys441 to the heme was altered with a significantly changed binding free energy for the mutant protein.

  3. results indicate that PGIS expression was associated with radiotherapy efficiency

  4. Type-2 diabetes is associated with higher COX-2 (Montrer COX2 Anticorps) expression, but lower eNOS (Montrer NOS3 Anticorps) and PGIS expression in subcutaneous arteries.

  5. In a case-control study unaffected carriers of a BMPR2 mutation, linked to pulmonary artery hypertension (PAH), were most often found to have prostacyclin synthase promoter sequence variants, which were thought to protect against PAH.

  6. These findings suggest that PGIS is induced by hypoxia and regulates the expression of VEGF (Montrer VEGFA Anticorps) in fibroblasts.

  7. High PTGIS expression is associated with colorectal cancer hepatic metastasis.

  8. The CC genotype of C1117A polymorphism is associated with higher risk of LM-CAD (Montrer CAD Anticorps)

  9. Overexpression of PTGIS is associated with liver metastasis in colon cancer.

  10. diabetes preferentially increases PGIS nitration that is associated with excessive vascular inflammation in atherosclerotic carotid arteries from patients with type 2 diabetes

Mouse (Murine) Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) interaction partners

  1. Prostacyclin synthase and prostaglandin E synthase (Montrer PTGES Anticorps)-1 cooperatively exacerbate inflammatory reactions but have opposing effects on carcinogenesis.

  2. Cyclooxygenase-2 (Montrer PTGS2 Anticorps)-derived prostacyclin regulates arterial thrombus formation by suppressing tissue factor (Montrer F3 Anticorps) in a sirtuin-1 (Montrer SIRT1 Anticorps)-dependent-manner.

  3. CD40 ligand (Montrer CD40LG Anticorps) might contribute to the initiation and progression of atherosclerosis by increasing activity of prostacyclin synthase.

  4. Sepiapterin not only reversed the effects of high glucose on both angiotensin II-induced relaxation and PGI(2 (Montrer PTGIR Anticorps)) release but also abolished high-glucose-enhanced PGIS nitration.

  5. Alpha(2)-adrenoreceptor activation is required for coupling heart rate to central inspiratory drive during acute hypoxia, and PGI(2 (Montrer PTGIR Anticorps)) is required to enhance the inhibition of sympathoactivation.

  6. The results provide strong evidence that the protective effects of COX-2 (Montrer COX2 Anticorps) within the liver are mediated through the production of PGE (Montrer LIPF Anticorps)(2) and PGI(2 (Montrer PTGIR Anticorps)), which exert anti-inflammatory functions.

  7. Endothelial PGI (Montrer BGN Anticorps) synthase-mediated prostacyclin contributes to renal protection against endotoxemia-related acute kidney injury.

  8. identify PGI(2)-prostaglandin I2 receptor (Montrer PTGIR Anticorps) as an important pathway for inhibiting allergic pulmonary inflammation by controlling recruitment of CD4 (Montrer CD4 Anticorps)(+) Th2 cells into the inflammatory site

  9. COX-1 (Montrer PTGS1 Anticorps) contributes to the enhanced formation of both PGI(2 (Montrer PTGIR Anticorps)) and TXA(2 (Montrer TBXA2R Anticorps)) in atherosclerosis, and to the development of the disease

  10. PGIS/ IP transgenic animals with lung-specific PPARgamma (Montrer PPARG Anticorps) overexpression also developed fewer lung tumors.

Zebrafish Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) interaction partners

  1. crystal structures of ligand-free, inhibitor (minoxidil)-bound and substrate analog U51605-bound PGIS

Pig (Porcine) Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) interaction partners

  1. Disturbances in prostacyclin synthase and its receptor may lead to disruption of the oviductal environment and, in turn, perturbed development of embryos and their transport to the uterus.

  2. Prostacyclin synthase is differentially expressed in the endometrium of cyclic and pregnant gilts resulting in higher PGI(2 (Montrer PTGIR Anticorps)) synthesis in pregnant animals

  3. CRP (Montrer CRP Anticorps) stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2 (Montrer PTGIR Anticorps)) synthesis.

Cow (Bovine) Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) interaction partners

Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) profil antigène

Profil protéine

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Gene names and symbols associated with PTGIS

  • prostaglandin I2 synthase (PTGIS) anticorps
  • prostaglandin I2 (prostacyclin) synthase (Ptgis) anticorps
  • prostaglandin I2 (prostacyclin) synthase (ptgis) anticorps
  • prostacyclin synthase (VDBG_06319) anticorps
  • prostaglandin I2 synthase (Ptgis) anticorps
  • Cyp8 anticorps
  • Cyp8a1 anticorps
  • Pgis anticorps
  • PTGI anticorps
  • PTGIS anticorps
  • ptgisl anticorps

Protein level used designations for PTGIS

cytochrome P450, family 8, subfamily A, polypeptide 1 , prostacyclin synthase , prostaglandin I2 synthase , prostaglandin I2 (prostacyclin) synthase like , prostaglandin I2 (prostacyclin) synthase , cytochrome P450 8A1

GENE ID SPECIES
5740 Homo sapiens
19223 Mus musculus
559148 Danio rerio
9535224 Verticillium alfalfae VaMs.102
458323 Pan troglodytes
703407 Macaca mulatta
100126284 Sus scrofa
100592236 Nomascus leucogenys
25527 Rattus norvegicus
282021 Bos taurus
100734621 Cavia porcellus
101116418 Ovis aries
100071412 Equus caballus
100856661 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour anti-Prostaglandin I2 (Prostacyclin) Synthase (PTGIS) Anticorps
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