Protease, serine, 8 (PRSS8) Kits ELISA

PRSS8 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. De plus, nous expédions Protease, serine, 8 Anticorps (101) et Protease, serine, 8 Protéines (11) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PRSS8 5652 Q16651
PRSS8 192107 Q9ES87
PRSS8 76560  
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Top Protease, serine, 8 Kits ELISA sur

Showing 10 out of 19 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.68 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests 13 to 16 Days
Souris 50pg/mL 0.78-50 ng/mL Mouse Prostasin PicoKine ELISA Kit standard curve 96 Tests 4 to 6 Days
Rat 1.95 ng/mL 3.9-250 ng/mL   96 Tests 15 to 18 Days
Porc 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Poulet 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Lapin 0.375 ng/mL 0.625-40 ng/mL   96 Tests 12 to 14 Days
Cobaye 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
Humain 3 pg/mL n/a   96 Tests 11 to 16 Days
  96 Tests 26 to 36 Days
Singe 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days

Protease, serine, 8 Kits ELISA mieux référencés

  1. Human PRSS8 Kit ELISA pour Sandwich ELISA - ABIN421905 : Yang, Zhang, Gong, Liu, Bai, Xu, Zhou: Increased expression of prostasin contributes to early-onset severe preeclampsia through inhibiting trophoblast invasion. dans Journal of perinatology : official journal of the California Perinatal Association 2014 (PubMed)

  2. Human PRSS8 Kit ELISA pour Sandwich ELISA - ABIN848315 : Andersen, Friis, Hansen, Svenningsen, Henriksen, Jensen: Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells. dans Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2015 (PubMed)

  3. Rat (Rattus) PRSS8 Kit ELISA pour Sandwich ELISA - ABIN848317 : Oxlund, Kurt, Schwarzensteiner, Hansen, Stæhr, Svenningsen, Jacobsen, Hansen, Thuesen, Toft, Hinrichs, Bistrup, Jensen: Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin. dans Pflügers Archiv : European journal of physiology 2018 (PubMed)

Plus Kits ELISA pour Protease, serine, 8 partenaires d'interaction

Human Protease, serine, 8 (PRSS8) interaction partners

  1. Compared with normal mucosa, PRSS8 mRNA levels were significantly reduced in colorectal adenocarcinomas. It was reduced in poorly differentiated cancers and in lymph node metastatic cancers in a progressive colorectal cancer tissue microarray.

  2. limited role for HAI-2 in the inhibition of matriptase and prostasin is the result of its primarily intracellular localization in basal and spinous layer keratinocytes, which probably prevents the Kunitz inhibitor from interacting with active prostasin or matriptase

  3. PRSS8 was downregulated in glioma tissues.PRSS8 role in the glioma cell proliferation, migration, and invasion.

  4. PRSS8 acts as a tumor suppressor in colorectal cancer

  5. Data show that PRSS8 was reduced in esophageal squamous cell carcinomas (ESCC) tissues and the reduction of PRSS8 was associated with poor differentiation and shorter survival time.

  6. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 and IL-13, down-regulates matriptase as well as prostasin through phosphorylation of the transcriptional regulator STAT6

  7. PRSS8 may serve as a tumour suppressor in hepatocellular carcinoma progression.

  8. Overexpression of PRSS8 mRNA and high levels of prostasin in multiple subtypes of early stage ovarian tumors may provide clinical biomarkers for early detection of ovarian cancer.

  9. It is concluded that prostasin protein level change is less likely to be causally involved in placental dysfunction in preeclampsia.

  10. In urinary exosomes, NCC and prostasin had a diurnal pattern parallel to ADH and aquaporin 2, confirming that, in healthy subjects, both prostasin and NCC relate to water balance.

  11. Polymorphism of the prostasin gene is closely associated with poor pregnancy outcomes of early-onset severe preeclampsia.

  12. Prostasin regulate the Lin28/Let-7 loop in ovarian cancer cells.

  13. The higher frequency of C allele of prostasin gene at rs12597511 is associated with severe preeclampsia.

  14. Prostasin repress cancer cells and contribute to chemoresistance by modulating the CASP/PAK2-p34/actin pathway.

  15. Our study suggested that Axl and prostasin expression may be closely related to carcinogenesis, metastasis, and prognosis of ovarian adenocarcinoma.

  16. urinary prostasin correlates with the aldosterone to renin ratio, and it is physiologically modulated by natriuresis in normotensive individuals

  17. prostasin is a non-enzymatic co-factor for matriptase activation

  18. Prostasin requires expression of endogenous matriptase to stimulate barrier formation since matriptase depletion by siRNA silencing abrogates prostasin barrier-forming activity.

  19. Essential hypertension in Xinjiang Kazakhs is not associated with the 2827C>T polymorphism in the prostasin gene.

  20. prostasin is present, mature and active on the apical surface of wild-type and cystic fibrosis bronchial epithelial cells

Mouse (Murine) Protease, serine, 8 (PRSS8) interaction partners

  1. Genetic Prss8 deficiency caused colitis and an inflamed rectum at an early age and intestinal tumors at a late age, with increased intestinal cell proliferation and migration but decreased cell differentiation. Increased PRSS8 inhibited cancer growth and metastasis in nude mice and inhibited cancer cell migration, invasion, colony and tumor sphere formation.PRSS8 targeted Wnt/beta-catenin, stem-cell, and EMT signaling.

  2. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 and IL-13, down-regulates matriptase as well as prostasin through phosphorylation of the transcriptional regulator STAT6

  3. a proteolysis-dependent function of activated prostasin in hair follicles, dependent on zymogen conversion by matriptase.

  4. The claudin-4-mediated chloride conductance can be regulated endogenously by a protease-channel-activating protease 1 (cap1).

  5. HAI-1 regulates the activity of activated matriptase, whereas HAI-2 has an essential role in regulating prostasin-dependent matriptase zymogen activation.

  6. a novel inhibitory interaction between CAP1/Prss8 and nexin-1, opening the search for specific CAP1/Prss8 antagonists that are independent of its catalytic activity

  7. Data indicate that liver-specific serine protease prostasin (PRSS8) knockout (LKO) mice develop insulin resistance associated with the increase in hepatic Toll-like receptor 4 (TLR4).

  8. Data indicate that serine protease prostasin (CAP1/PRSS8) supports terminal epidermal differentiation through a non-catalytic mechanism.

  9. mutations in Prss8 restored placentation and normal development of HAI-1-deficient embryos and prevented early embryonic lethality, mid-gestation lethality due to placental labyrinth failure, and neural tube defects in HAI-2-deficient embryos.

  10. Mutations of the serine protease CAP1/Prss8 lead to reduced embryonic viability, skin defects, and decreased ENaC activity.

  11. The T to A mutation at residue 170 (Val to Asp) in Prss8 is responsible for the mutant frizzy (fr) phenotype.

  12. Deficiency of CAP1/Prss8 in alveolar epithelial cells induced in vitro a 40% decrease in epithelial sodium channel-mediated sodium currents.

  13. 546 backcross progeny were typed for linked markers to position fr centromeric of Fgfr2, between D7Csu5 and D7Mit165; an interval that contains only 2.7 Mb and fewer than 70 genes

  14. conditional allelle mutations at Prss8 can be generated by Cre- and FLP-mediated recombination

  15. CAP1/Prss8 expression in the epidermis is crucial for the epidermal permeability barrier and is, thereby, indispensable for postnatal survival.

  16. mutations in conserved residues of mCAP2 located in two protein-protein interacting domains significantly modulated ENaC activation

  17. findings demonstrate that prostasin is expressed in bladder epithelium; expression is downregulated during inflammation produced by intraperitoneal LPS injection; prostasin may play a role in bladder inflammatory response by modulating cytokine signaling

  18. Results suggest that cell-specific Gpld1- or peptidase-dependent pathways for prostasin secretion may control prostasin functions in a tissue-specific manner.

  19. Results indicate that PN-1 could have a natriuretic role by inhibiting prostasin activity. Aldosterone and TGF-beta reciprocally regulate the expression of PN-1. PN-1 could represent a new factor that contributes to regulation of ENaC activity.

Protease, serine, 8 (PRSS8) profil antigène

Antigen Summary

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

Gene names and symbols associated with Protease, serine, 8 (PRSS8) Kits ELISA

  • protease, serine 8 (PRSS8) anticorps
  • protease, serine, 8 (Prss8) anticorps
  • protease, serine 8 (prostasin) (Prss8) anticorps
  • protease, serine, 8 (PRSS8) anticorps
  • 2410039E18Rik anticorps
  • AI313909 anticorps
  • C79772 anticorps
  • CAP1 anticorps
  • fr anticorps
  • mCAP1 anticorps
  • prostasin anticorps

Protein level used designations for Protease, serine, 8 (PRSS8) Kits ELISA

channel-activating protease 1 , prostasin , serine protease 8 , channel activating protease 1

5652 Homo sapiens
192107 Rattus norvegicus
613506 Bos taurus
76560 Mus musculus
102148278 Equus caballus
102157328 Canis lupus familiaris
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