Proteasome Maturation Protein (POMP) Kits ELISA

The protein encoded by POMP is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. De plus, nous expédions POMP Anticorps (28) et POMP Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
POMP 51371 Q9Y244
POMP 66537 Q9CQT5
Anti-Rat POMP POMP 288455  
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Plus Kits ELISA pour POMP partenaires d'interaction

Human Proteasome Maturation Protein (POMP) interaction partners

  1. POMP-related autoinflammation and immune dysregulation disease (PRAID) discovered in two unrelated individuals with a unique constellation of early-onset combined immunodeficiency, inflammatory neutrophilic dermatosis, and autoimmunity, is reported.

  2. POMP is overexpressed and participates in the increase of proteasome assembly and activity in psoriatic skin.

  3. MCM3AP and POMP Mutations Cause a DNA-Repair and DNA-Damage-Signaling Defect in an Immunodeficient Child

  4. studies validate a role for the NRF2/POMP axis in bortezomib resistance and identify NRF2 and POMP as potentially attractive targets for chemosensitization to this proteasome inhibitor

  5. microRNA-101 (miR-101) targets the proteasome maturation protein POMP, leading to impaired proteasome assembly and activity, and resulting in accumulation of p53 and cyclin-dependent kinase inhibitors, cell cycle arrest, and apoptosis.

  6. Single-nucleotide polymorphisms in POMP gene is associated with breast cancer risk after menopausal hormone replacement therapy.

  7. KLICK is caused by reduced levels of POMP, leading to proteasome insufficiency in differentiating keratinocytes

  8. A single-nucleotide deletion in the POMP 5' UTR causes a transcriptional switch and altered epidermal proteasome distribution in KLICK genodermatosis.

  9. POMP/proteassemblin/hUmp1 may be tetramerised and is localized to the cytoplasm and the nucleus

  10. Data show that POMP facilitates the main steps in 20S core complex formation at the ER to coordinate the assembly process and to provide cells with freshly formed proteasomes at their site of function.

POMP profil antigène

Antigen Summary

The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.

Gene names and symbols associated with POMP

  • proteasome maturation protein S homeolog (pomp.S) anticorps
  • proteasome maturation protein (POMP) anticorps
  • proteasome maturation protein (pomp) anticorps
  • proteasome maturation protein (Pomp) anticorps
  • 2510048O06Rik anticorps
  • C13orf12 anticorps
  • fa13f09 anticorps
  • MGC81104 anticorps
  • MGC89819 anticorps
  • PNAS-110 anticorps
  • RGD1305831 anticorps
  • Ump1 anticorps
  • wu:fa13f09 anticorps
  • zgc:92775 anticorps

Protein level used designations for POMP

proteasome maturation protein , 2510048O06Rik , hUMP1 , proteassemblin , protein UMP1 homolog , voltage-gated K channel beta subunit 4.1 , voltage-gated potassium channel beta subunit 4.1 , mUMP1

414726 Xenopus laevis
418925 Gallus gallus
448670 Xenopus (Silurana) tropicalis
445030 Danio rerio
100168236 Acyrthosiphon pisum
100528728 Ictalurus punctatus
51371 Homo sapiens
66537 Mus musculus
288455 Rattus norvegicus
510314 Bos taurus
100172839 Pongo abelii
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