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may regulate renin release and renal ion transport. De plus, nous expédions Protein Kinase, CGMP-Dependent, Type II Anticorps (68) et et beaucoup plus de produits pour cette protéine.
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Mouse (Murine) PRKG2 Kit ELISA pour Sandwich ELISA - ABIN430219
Tripathi, Sullivan, Fan, Wang, Sun, Reed, Gladysheva: Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy. dans PLoS ONE 2017
This study indicates that loss of PRKG2 function results in differential expression of P53 (Montrer TP53 Kits ELISA) regulated genes as well as additional pathways consistent with increased proliferation and apoptosis in the growth plate due to achondroplastic dwarfism.
PRKG2 R678X as a causative mutation for dwarfism cattle was presented.
L-Arginine (Montrer GATM Kits ELISA) is a potential alternative to PKG (Montrer PRKG1 Kits ELISA) II activation.
Comparative analysis of the backbone hydrogen/deuterium exchange patterns in PKG (Montrer PRKG1 Kits ELISA) II:8-pCPT-cGMP and previously reported PKG (Montrer PRKG1 Kits ELISA) Ibeta:cGMP XN structures suggests that the ability of these agonists to activate PKG (Montrer PRKG1 Kits ELISA) is related to how effectively they quench dynamics of the cyclic nucleotide binding pocket and the surrounding regions.
the results indicated that PKG II could block c-Met activation via phosphorylating Ser985
These affinity and activation measurements show that beta-phenyl-1,N2-ethenoguanosine 3',5'-monophosphate (PET-cGMP) is most selective for PKG (Montrer PRKG1 Kits ELISA) I, whereas 8-(4-chlorophenylthio)guanosine-3'-5'-cyclic monophosphate (8-pCPT-cGMP) is most selective for PKG (Montrer PRKG1 Kits ELISA) II.
PKG (Montrer PRKG1 Kits ELISA) II inhibits EGFinduced activation of HER2 (Montrer ERBB2 Kits ELISA) through binding with and causing threonine 686 phosphorylation of this oncogenic protein.
The C-terminal cyclic nucleotide binding (CNB (Montrer PPP3R1 Kits ELISA)-B) domain of cGMP-dependent protein kinase II binds cGMP with higher affinity and selectivity when compared with its N-terminal CNB (CNB (Montrer PPP3R1 Kits ELISA)-A) domain.
Han Chinese patients with rs10033237 polymorphism of cGKII/PRKG2 gene are more likely to suffer from gout.
Our replication study suggests that cGKII is not involved in gout susceptibility.
we determined a crystal structure of the PKG (Montrer PRKG1 Kits ELISA) II LZ-Rab11b (Montrer RAB11B Kits ELISA) complex. The PKG (Montrer PRKG1 Kits ELISA) II LZ domain presents a mostly nonpolar surface onto which Rab11b (Montrer RAB11B Kits ELISA) docks, through van der (Montrer GDF3 Kits ELISA) Waals interactions
PKGII inhibits RhoA (Montrer RHOA Kits ELISA) activity by binding to this small GTPase (Montrer RACGAP1 Kits ELISA) and causing phosphorylation at its Ser188 site.
Study shows that there are brain region-specific effects of cGMP-dependent protein kinase II knock-out on AMPA (Montrer GRIA3 Kits ELISA) receptor trafficking that affects animal behavior. Study shows that GluA1 (Montrer GRIA1 Kits ELISA) phosphorylation levels differ in various brain regions, and specific behaviors are altered according to region-specific changes in GluA1 (Montrer GRIA1 Kits ELISA) phosphorylation.
cGKII may play a role in the integration of information that conveys both anxiety-provoking stimuli as well as the spatial and environmental cues that facilitate functional memory processes and appropriate behavioral response.
urine volume was decreased significantly in cGKII-KO subjected to volume load.
Cyclic GMP kinase (Montrer GUK1 Kits ELISA) II (cGKII) inhibits NHE3 (Montrer SLC9A3 Kits ELISA) by altering its trafficking and phosphorylating NHE3 (Montrer SLC9A3 Kits ELISA) at three required sites
Increased PKG2 activity alters homeostasis by suppressing proliferation and apoptosis while promoting differentiation. The PKG2-dependent mechanism was shown to involve increased DUSP10 and subsequent inhibition of JNK (Montrer MAPK8 Kits ELISA) activity.
cGKII KO mice are significantly deficient in spatial learning while exhibiting facilitated motor coordination. Data suggest that the role of cGKII may be more robust in particular regions.
cGKII and HCN2 (Montrer HCN2 Kits ELISA) interact and colocalize with each other
The homeobox (Montrer PRRX1 Kits ELISA) gene Nkx family is critical for the transcriptional regulation of cGK-II during chondrogenesis.
Inhibition of cGMP-dependent protein kinase II by its own splice isoform
study provides in vivo and in vitro genetic evidence that cGKII plays a critical role in C-type natriuretic peptide (Montrer NPPC Kits ELISA)-mediated endochondral ossification
may regulate renin release and renal ion transport
protein kinase, cGMP-dependent, type II
, cGMP-dependant type II protein kinase
, cGMP-dependent protein kinase 2
, cGMP-dependent protein kinase 2-like
, cGK 2
, cGMP-dependent protein kinase II
, CGK 2
, cGMP dependent protein kinase type II
, protein kinase cGMP- dependent type 2
, protein kinase, cGMP- dependent, type 2
, protein kinase, cGMP- dependent, type II
, type II cGMP-dependent protein kinase