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Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombos. De plus, nous expédions Protein O-Fucosyltransferase 2 Protéines (4) et beaucoup plus de produits pour cette protéine.
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Cow (Bovine) Polyclonal POFUT2 Primary Antibody pour WB - ABIN2782385
Luo, Nita-Lazar, Haltiwanger: Two distinct pathways for O-fucosylation of epidermal growth factor-like or thrombospondin type 1 repeats. dans The Journal of biological chemistry 2006
Show all 2 Pubmed References
This study demonstrated that the alteration of POFUT2 expression in the superior temporal gyrus of elderly patients with schizophrenia.
POFUT2 and B3GLCT (Montrer B3GALTL Anticorps) mediate a noncanonical endoplasmic reticulum quality-control mechanism that recognizes folded thrombospondin type 1 repeats and stabilizes them by glycosylation.
Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O-fucosylation.
cDNA sequences and genomic structure of POFUT2 are reported.
Pofut2 was required during mouse gastrulation to coordinate morphogenetic movements and specify a range of tissues in the mouse embryo.
Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF\; MIM 131530)-like repeats or thrombospondin (THBS\; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006
GDP-fucose protein O-fucosyltransferase 2
, peptide-O-fucosyltransferase 2
, putative protein-O-fucosyltransferase
, protein O-fucosyltransferase 2a
, protein O-fucosyltransferase 2c
, protein O-fucosyltransferase 2d
, protein O-fucosyltransferase 2e