Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Protéines
The protein encoded by PPM1A is a member of the PP2C family of Ser/Thr protein phosphatases.
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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein (His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein (His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein (His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Active) Protéine Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Active) Protéine Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) Protéine Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Transcript Variant 1) protein (His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) protein (GST tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein (T7 tag,His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein (His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) protein (His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) protein (His tag) Protein
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Protéine Protein
Profil protéine Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Profil protéine
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene names and symbols associated with PPM1A
- protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A) anticorps
- protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a) anticorps
- protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a) anticorps
- protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L) anticorps
- protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a) anticorps
- protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa) anticorps
- 2310003C21Rik anticorps
- 2900017D14Rik anticorps
- AI427932 anticorps
- AU017636 anticorps
- MMPa-2 anticorps
- MPPa-1 anticorps
- pp2c-alpha anticorps
- Pp2c1 anticorps
- pp2ca anticorps
- pp2ca2 anticorps
- pp2calpha anticorps
Protein level used designations for PPM1A
protein phosphatase 1A , protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform , Mpp alpha , PP2C-alpha , protein phosphatase 2C isoform alpha , protein phosphatase IA , IA , Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform , Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform , protein phosphatase 1A, magnesium dependent, alpha isoform , protein phosphatase 2C alpha , protein phosphatase type 2C alpha 2
| GENE ID | SPECIES |
|---|---|
| 5494 | Homo sapiens |
| 19042 | Mus musculus |
| 24666 | Rattus norvegicus |
| 380058 | Xenopus laevis |
| 423525 | Gallus gallus |
| 480344 | Canis lupus familiaris |
| 281994 | Bos taurus |
| 100009431 | Oryctolagus cuniculus |
| 100738389 | Sus scrofa |
| 100734826 | Cavia porcellus |
| 30704 | Danio rerio |
