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Regulatory subunit of protein phosphatase 1 (By similarity).. De plus, nous expédions Protein Phosphatase 1, Regulatory Subunit 7 Anticorps (51) et Protein Phosphatase 1, Regulatory Subunit 7 Protéines (8) et beaucoup plus de produits pour cette protéine.
a Fra-1 (Montrer FOSL1 Kits ELISA)-miR (Montrer MLXIP Kits ELISA)-134 axis drives a positive feedback loop that amplifies ERK (Montrer EPHB2 Kits ELISA)/JNK (Montrer MAPK8 Kits ELISA) signaling and reduces chemosensitivity in ovarian cancer cells.
Mechanistically, the phosphorylation of Sds22 by PLK1 (Montrer PLK1 Kits ELISA) strengthens the binding of Sds22 to PP1 (Montrer PPA1 Kits ELISA) and inhibits the dephosphorylation of Thr (Montrer TRH Kits ELISA)(232) of Aurora B (Montrer AURKB Kits ELISA) to ensure a robust, error-free metaphase-anaphase transition.
there is a second, parallel signalling pathway which triggers the relaxation of the polar cell cortex at mid anaphase--independent of furrow formation, centrosomes and microtubules, pathway depends on PP1 (Montrer PPA1 PLURAL_@12788@) phosphatase and regulatory subunit Sds22
a model in which I3 regulates an SDS22-mediated PP1 (Montrer PPA1 Kits ELISA) activation step in solution that precedes SDS22 dissociation and transfer of PP1 (Montrer PPA1 Kits ELISA) to kinetochores, and which is required for PP1 (Montrer PPA1 Kits ELISA) to efficiently antagonize Aurora B (Montrer AURKB Kits ELISA).
It was shown that Repo-Man (Montrer CDCA2 Kits ELISA) and Sds22 contribute to timely Aurora B kinase (Montrer AURKB Kits ELISA) substrate dephosphorylation on anaphase chromatin.
human Sds22 is focally deleted and downregulated in multiple carcinomas, and this downregulation correlates with tumor progression, suggesting that sds22 inactivation may contribute to tumorigenesis and metastatic potential
Sds22 specifically defines protein phosphatase 1 (Montrer PPP1CB Kits ELISA) function and localization in mitosis.
Sds22 and Inhibitor-3 (Montrer PPP1R11 Kits ELISA) form a heterotrimeric complex with PP1 (Montrer PPA1 Kits ELISA), both in cell lysates and after purification. A pool of PP1 (Montrer PPA1 Kits ELISA) is complexly controlled by both Sds22 and Inhibitor-3 (Montrer PPP1R11 Kits ELISA).
Regulatory subunit of protein phosphatase 1 (By similarity).
protein phosphatase 1 regulatory subunit 22
, protein phosphatase 1 regulatory subunit 7
, protein phosphatase-1 regulatory subunit 7
, protein phosphatase 1, regulatory (inhibitor) subunit 7
, protein phosphatase-1 regulatory subunit 7 alpha2
, protein phosphatase-1 regulatory subunit 7 beta1
, protein phosphatase-1 regulatory subunit 7 beta2