anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) Anticorps

The protein encoded by PTPRA is a member of the protein tyrosine phosphatase (PTP) family. De plus, nous expédions PTPRA Protéines (14) et PTPRA Kits (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PTPRA 5786 P18433
PTPRA 19262 P18052
PTPRA 25167  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-PTPRA Anticorps sur anticorps-enligne.fr

Showing 10 out of 135 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PTPRA Antibody Titration:  0.2-1 ug/ml  Positive Control:  293T cell lysate PTPRA is supported by BioGPS gene expression data to be expressed in HEK293T 100 μL 2 to 3 Days
$289.00
Détails
Poulet Lapin Inconjugué WB   200 μL 13 to 14 Days
$575.00
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué WB   200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HeLa cells treated with serum 20% 15', using PTPRA (Phospho-Tyr798) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, IHC, WB ABIN6269914 at 1/100 staining mouse lung tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6269914 at 1/100 staining human gastric cancer tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$450.00
Détails
Humain Lapin Inconjugué IHC, IHC (p) Anti-PTPRA antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049272 concentration 4 ug/ml. Anti-PTPRA antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049272 concentration 4 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p) Anti-PTPRA antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049270 dilution 10 ug/ml. Anti-PTPRA antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049270 dilution 10 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p) Anti-PTPRA antibody IHC staining of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049271 dilution 4 ug/ml. Anti-PTPRA antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049271 dilution 4 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails

anti-PTPRA Anticorps mieux référencés

  1. Bat Polyclonal PTPRA Primary Antibody pour IHC (p) - ABIN271250 : Wu, Kao, Li, Chi, Lin: Protein tyrosine-phosphatase expression profiling in gastric cancer tissues. dans Cancer letters 2006 (PubMed)

  2. Human Polyclonal PTPRA Primary Antibody pour ELISA, WB - ABIN545016 : Kaplan, Morse, Huebner, Croce, Howk, Ravera, Ricca, Jaye, Schlessinger: Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain. dans Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre PTPRA partenaires d’interaction

Human Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) interaction partners

  1. Multivariate Cox regression analysis suggested that PTPRA expression was an independent prognostic factor in SCC patients. In the cellular models, PTPRA promotes SCC cell proliferation through modulating Src activation as well as cell cycle progression. In conclusion, higher PTPRA level was associated with worse prognosis of SCC patients and PTPRA could promote the cell cycle progression

  2. VacA mediates CagA phosphorylation through RPTPalpha in AZ-521 cells.

  3. A receptor type-protein tyrosine phosphatase alpha-Src family kinase-Rap1 pathway was identified as responsible for recruiting myosin IIB to the zonula adherens in epithelial cells and supporting contractile tension.

  4. no evidence was seen for the association of rare, missense mutations in the PTPRA gene with schizophrenia or autism spectrum disorders

  5. Data indicate that scaffold protein RACK1 plays a role in IGF-1-mediated protein-tyrosine phosphatase alpha (PTPalpha) tyrosine phosphorylation in MCF-7 Cells.

  6. recruited to epithelial adherens junctions for cadherin-dependent cell adhesion and tissue architecture formation

  7. Results suggest that inhibition of PTPalpha can have a beneficial effect on HER2-positive breast cancers, but that inhibition of additional targets is needed to block breast tumorigenesis.

  8. new role for PTPalpha in the regulation of motility of mammary epithelial cells in response to ErbB2 activation.

  9. results suggest that PTPalpha links activation of epidermal growth factor receptor (EGFR) signaling with Src activation and may provide a novel therapeutic target for treatment of breast cancer.

  10. A single-nucleotide polymorphism (rs6138953) on the PTPRA gene in the 20p13 region was found to be associated with elevated fasting glucose level.

  11. The extracellular proteolytic processing is a novel mechanism for PTPalpha regulation.

  12. our results suggest that plasma PTPalpha and fibronectin may be associated with opisthorchiasis.

  13. convergent evidence reported here links RPTP to schizophrenia.

  14. The transformed cells were tumourigenic in nude mice, suggesting that RPTPalpha245-induced activation of Src in the human tumours may have contributed to carcinogenesis.

  15. the PTPalpha-mediated increase of NB-3 level at the cell surface represents a novel function of PTPalpha in NB-3 signaling in neural development

  16. a novel role for E-loop residue Lys182 in enhancing HePTP catalytic activity through its interaction with Asp236 of the WPD loop was revealed.

  17. IL-1-induced signaling through focal adhesions leading to MMP3 release and interactions between SHP-2 and PTPalpha are dependent on the integrity of the catalytic domains of PTPalpha.

  18. force-responsive proteins such as RPTPalpha can influence cancer-cell behavior and identify potential targets for cancer therapy.

  19. Physical and functional interactions between protein tyrosine phosphatase alpha, PI 3-kinase, and PKCdelta.

  20. In entering mitosis the cell cycle-specific regulation of c-Src by RPTPalpha can occur by dephosphorylation of phospho-Tyr527 that activates c-Src in a reaction catalyzed by the transmembrane receptor-like protein tyrosine phosphatase RPTPalpha.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) interaction partners

  1. In a model of spinal cord injury, blocking PTPalpha and LAR receptors promotes oligodendrogenesis.

  2. PTPalpha coordinates oligodendroglial and neuronal development and myelination.

  3. RPTPalpha mediates proinflammatory and proinvasive signaling in rheumatoid arthritis fibroblast-like synoviocytes (FLS), correlating with the promotion of disease in an FLS-dependent model of rheumatoid arthritis.

  4. Ptpra coordinates the regulation of the Fyn signaling pathway in corpus striatum.

  5. PTPs alpha and epsilon play distinct roles in osteoclasts.

  6. PTP-alpha promotes profibrotic signaling pathways in fibroblasts through control of cellular responsiveness to TGF-beta.

  7. The focal adhesion targeting domain of FAK interacts with protein-tyrosine phosphatase-alpha to restrict IL1-induced Ca2+ release, ERK activation, and MMP-9 expression.

  8. PTPalpha may be involved in the formation of axoglial junctions and ensheathment in small axons during myelination of the spinal cord.

  9. Findings indicate Grb2 as a new FAK activator and in coordinating PTPalpha tyrosine phosphorylation to enable downstream integrin signaling and migration.

  10. Results suggest that inhibition of PTPalpha can have a beneficial effect on HER2-positive breast cancers, but that inhibition of additional targets is needed to block breast tumorigenesis.

  11. Inflammation-induced connective tissue degradation involving fibroblasts requires functionally active PTPalpha.

  12. study described a molecular complex of PTPalpha-BCAR3-Cas-Src; this complex forms in response to PTPalpha Tyr789 phosphorylation and mediates Cas localization to focal adhesions and Cas downstream signaling to promote cell migration

  13. Protein-tyrosine phosphatase alpha acts in oligodendrocyte progenitor cells to limit self-renewal and facilitate differentiation.

  14. protein kinase C and protein tyrosine phosphatase alpha participate in Src activation by 1alpha,25OH2 vitamin D3 in C2C12 skeletal muscle cells

  15. the PTPalpha-mediated increase of NB-3 level at the cell surface represents a novel function of PTPalpha in NB-3 signaling in neural development

  16. these findings indicate that PTPalpha acts as an Ag-stimulated Lyn-Fyn phosphatase and a critical positive regulator of these Src family kinases in FcepsilonRI signaling

  17. The results suggest that transformation by PTPalpha involves at least one function other than, or in addition to, its activation of Src and that this depends on PTPalpha's extracellular domain.

  18. Expression of CD45RA and -RC isoforms is increased 20- to 200-fold on T cells from mice with a loss-of-function mutation in RNA-binding protein heterogeneous nuclear ribonucleoprotein L-like, although total CD45 expression is unaltered.

  19. Results describe the role of nitric oxide in regulating the focal adhesion proteins, Src, FAK, p130 Cas, and PTP-alpha.

  20. IL-1-induced signaling through focal adhesions leading to MMP3 release and interactions between SHP-2 and PTPalpha are dependent on the integrity of the catalytic domains of PTPalpha.

Zebrafish Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) interaction partners

  1. ptpra protein, zebrafish, signaling is essential for convergence and extension cell movements during gastrulation.

PTPRA profil antigène

Profil protéine

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Gene names and symbols associated with PTPRA

  • protein tyrosine phosphatase, receptor type A (PTPRA) anticorps
  • protein tyrosine phosphatase, receptor type A (ptpra) anticorps
  • protein tyrosine phosphatase, receptor type, A (PTPRA) anticorps
  • protein tyrosine phosphatase, receptor type, A (Ptpra) anticorps
  • protein tyrosine phosphatase, receptor type, A (ptpra) anticorps
  • protein tyrosine phosphatase, receptor type A S homeolog (ptpra.S) anticorps
  • HEPTP anticorps
  • HLPR anticorps
  • HPTPA anticorps
  • HPTPalpha anticorps
  • LRP anticorps
  • Ptpa anticorps
  • ptpa-a anticorps
  • Ptpalpha anticorps
  • PTPRA anticorps
  • PTPRL2 anticorps
  • R-PTP-alpha anticorps
  • RPTPA anticorps
  • Rptpalpha anticorps
  • RPTP[a] anticorps
  • Rptra anticorps
  • Rptralpha anticorps
  • zf-RPTP[a] anticorps

Protein level used designations for PTPRA

protein tyrosine phosphatase, receptor type, A , receptor-type tyrosine-protein phosphatase alpha-like , Leukocyte common antigen-related peptide (protein tyrosine phosphate) , PTPLCA-related phosphatase , PTPase-alpha , protein tyrosine phosphatase, receptor type, alpha polypeptide , protein-tyrosine phosphatase alpha , receptor-type tyrosine-protein phosphatase alpha , tyrosine phosphatase alpha , LCA-related phosphatase , PTPTY-28 , R-PTP-alpha , protein tyrosine phosphatase alpha , protein tyrosine phosphatase receptor type alpha , protein-tyrosine-phosphatase alpha

GENE ID SPECIES
100066880 Equus caballus
574364 Macaca mulatta
746684 Pan troglodytes
100017832 Monodelphis domestica
100158513 Xenopus (Silurana) tropicalis
100342875 Oryctolagus cuniculus
100373726 Saccoglossus kowalevskii
100404748 Callithrix jacchus
100449130 Pongo abelii
100464070 Ailuropoda melanoleuca
100605844 Nomascus leucogenys
5786 Homo sapiens
19262 Mus musculus
25167 Rattus norvegicus
140818 Danio rerio
394358 Xenopus laevis
396060 Gallus gallus
477176 Canis lupus familiaris
100138017 Bos taurus
100157496 Sus scrofa
Fournisseurs de qualité sélectionnés pour anti-PTPRA (PTPRA) Anticorps
Avez-vous cherché autre chose?