anti-Proteolipid Protein 1 (PLP1) Anticorps

PLP1 encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain PLP1 PLP1 5354 P60201
Anti-Rat PLP1 PLP1 24943 P60203
Anti-Souris PLP1 PLP1 18823 P60202
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Top anti-Proteolipid Protein 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 49 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-PLP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  721_B cell lysate Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5µg/ml using anti-PLP1 antibody (ARP33843_P050) 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PLP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Hela cell lysate Host:  Mouse  Target Name:  PLP1  Sample Tissue:  Mouse Heart  Antibody Dilution:  1ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Souris Inconjugué FACS, IHC (fro), IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 6 to 8 Days
$544.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of Myelin PLP expression in rat brain extract ( Lane 1), mouse brain extract ( Lane 2) and SHG-44 whole cell lysates ( Lane 3). Myelin PLP at 34KD was detected using rabbit anti- Myelin PLP Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué IP, WB PLP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLP1 expression in mouse testis. PLP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLP1 expression in A-431. 100 μL Connectez-vous pour afficher 11 to 12 Days
$425.71
Détails
Souris Lapin Inconjugué ICC, WB Western Blot: Myelin PLP Antibody [ABIN2615973] - Analysis of adult mouse brain samples. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Boeuf (Vache) Souris Inconjugué IHC, IHC (fro), IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PLP1 antibody ABIN364261 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PLP1 antibody ABIN364261 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB Anti-PLP1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959011 concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 7 to 9 Days
$727.83
Détails
Humain Souris Inconjugué ICC, IHC, IHC (fro), IHC (p), WB Anti-PLP1 antibody IHC staining of human brain cerebellum, neuropil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103681 dilution 10 ug/ml. 50 μg Connectez-vous pour afficher 7 to 9 Days
$727.83
Détails
Humain Poulet Inconjugué ICC, IF, IHC (p), IHC, WB In this tissue section through an e 13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei. 0.25 mL Connectez-vous pour afficher 7 to 9 Days
$415.44
Détails

anti-Proteolipid Protein 1 Anticorps mieux référencés

  1. Cow (Bovine) Monoclonal PLP1 Primary Antibody pour IHC (fro), FACS - ABIN2475779 : Ballard: Retrospective studies of left atrial thrombus: does misclassification impair their clinical utility? dans Journal of general internal medicine 1991 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Polyclonal PLP1 Primary Antibody pour ICC, WB - ABIN261597 : Horiuchi, Maezawa, Itoh, Wakayama, Jin, Itoh, Decarli: Amyloid β1-42 oligomer inhibits myelin sheet formation in vitro. dans Neurobiology of aging 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal PLP1 Primary Antibody pour ICC, IF - ABIN151155 : Cachón-González, Wang, Ziegler, Cheng, Cox: Reversibility of neuropathology in Tay-Sachs-related diseases. dans Human molecular genetics 2014 (PubMed)

Plus d’anticorps contre Proteolipid Protein 1 partenaires d’interaction

Human Proteolipid Protein 1 (PLP1) interaction partners

  1. Authors investigated the disease progression in mouse models carrying PLP1 point mutations previously found in patients displaying clinical features of multiple sclerosis. These mouse models show loss-of-function of PLP1 associated with neuroinflammation.

  2. Review focusing on sequences in hPLP1 intron 1 DNA deemed important for hPLP1 gene activity as well as a couple of "human-specific" supplementary exons within the first intron which are utilized to generate novel splice variants, and the potential role that these sequences may play in PLP1-linked disorders.

  3. it seems that the epitopes of some microorganisms mimicking PLP such as PLP58-74 might have a potential role in the initiation of Multiple Sclerosis.

  4. Human induced pluripotent stem cells-derived oligodendrocytes from 12 individuals with Pelizaeus-Merzbacher and identified individual and shared defects in PLP1 mRNA expression and splicing, oligodendrocyte progenitor development, and oligodendrocyte morphology and capacity for myelination.

  5. report a novel mutation of the PLP1 gene in two siblings with Pelizaeus-Merzbacher disease associated with a rare and protean neuroimaging finding of optic nerve enlargement

  6. Identification and functional study of novel PLP1 mutations in Chinese patients with Pelizaeus-Merzbacher disease. We identified PLP1 mutations in seven male patients with PMD.

  7. In major depressive disorder there was a significantly reduced expression of PLP1 mRNA.

  8. Study investigated 17 unrelated Pelizaeus-Merzbacher disease subjects with copy number gains at the PLP1 locus including triplication and quadruplication of specific genomic intervals-16/17 were found to have a duplication-inverted triplication-duplication rearrangement product.

  9. Myelin proteolipid protein is critical to regulating oligodendrocyte progenitor cell migration.

  10. PLP1 splicing mutations may result in a wide variety of disease phenotypes through a combination of multiple molecular pathogenic mechanisms.

Mouse (Murine) Proteolipid Protein 1 (PLP1) interaction partners

  1. This study demonstrated that Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2.

  2. The rumpshaker missense mutation in the Plp1 gene gives rise to subcortical myoclonus

  3. axonal mitochondria, smooth endoplasmic reticulum, and microtubules were characterized in rodent optic nerves where PLP (Montrer C3 Anticorps) is replaced by the peripheral nerve myelin protein, P0.

  4. The observations collectively support the idea that GST-pi (Montrer GSTP1 Anticorps)(Nuc (Montrer SREBF2 Anticorps))/DM-20 mRNA-expressing cells are the progeny of NG2 (Montrer Vcan Anticorps)-positive OPCs rather than a novel type of oligodendrocyte-lineage progenitor cells and that DM-20 mRNA expression is dynamically regulated during differentiation of OPCs into oligodendrocytes.

  5. In the absence of P0, thus, PLP (Montrer C3 Anticorps) also contributes to myelination by Schwann cells and to the preservation of peripheral axons

  6. while PLP (Montrer C3 Anticorps) can co-exist with P0 in peripheral nervous system(PNS) myelin, PLP (Montrer C3 Anticorps) cannot replace P0 as the major structural protein of PNS myelin.

  7. Both extracellular and intracellular epitopes of PLP (Montrer C3 Anticorps) contribute to the pathogenesis of MP4-induced experimental autoimmune encephalomyelitis already in the setting of intact myelin.

  8. The insertion of native PLP (Montrer C3 Anticorps) into Olg mitochondria of animals with PLP1/Plp1 regulates extracellular pH and adenosine triphosphate.

  9. This study shows for the first time that Plp (Montrer C3 Anticorps)-null mice exhibit severe early-onset thermal hyperalgesia that is not associated with changes in thermal allodynic behavior.

  10. A novel mechanism sheds light on the immune regulation by which sulfatide-reactive type II natural killer (NK)T cells suppress inflammatory class II histocompatibility-restricted pathogenic CD4 (Montrer CD4 Anticorps)+ T cell responses in a T cell-mediated autoimmune disease.

Proteolipid Protein 1 (PLP1) profil antigène

Profil protéine

This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.

Gene names and symbols associated with PLP1

  • proteolipid protein 1 (PLP1) anticorps
  • proteolipid protein 1 (Plp1) anticorps
  • proteolipid protein 1 (plp1) anticorps
  • proteolipid protein (myelin) 1 (Plp1) anticorps
  • myelin proteolipid protein (Tsp_11640) anticorps
  • myelin proteolipid protein (plp) anticorps
  • proteolipid protein 1 L homeolog (plp1.L) anticorps
  • proteolipid protein 1a (plp1a) anticorps
  • DKFZp459O081 anticorps
  • DKFZp459O113 anticorps
  • DM20 anticorps
  • DMalpha2c anticorps
  • GPM6C anticorps
  • hld1 anticorps
  • jimpy anticorps
  • jp anticorps
  • mmpl anticorps
  • msd anticorps
  • plp anticorps
  • PLP/DM20 anticorps
  • plp1 anticorps
  • plp1a anticorps
  • pmd anticorps
  • rsh anticorps
  • spg2 anticorps
  • wu:fc27f01 anticorps
  • wu:fj36d03 anticorps
  • wu:fj42d08 anticorps
  • zgc:110499 anticorps

Protein level used designations for PLP1

lipophilin , major myelin proteolipid protein , myelin proteolipid protein , Proteolipid protein (Pelizaeus-Merzbacher disease spastic paraplegia 2 uncomplicated) , Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) , proteolipid protein (myelin) 1 , proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) , proteolipid protein, lipophilin , proteolipid protein 1 , myelin synthesis deficiency , rump shaker , PLP , PLP-A , lipophilin-A , myelin proteolipid protein (PLP) , myelin proteolipid protein A , proteolipid protein 1 a , DMalpha1 , etID60288.14

GENE ID SPECIES
5354 Homo sapiens
24943 Rattus norvegicus
281410 Bos taurus
397029 Sus scrofa
465785 Pan troglodytes
481002 Canis lupus familiaris
613099 Xenopus (Silurana) tropicalis
100009169 Oryctolagus cuniculus
100173486 Pongo abelii
100174736 Pongo abelii
18823 Mus musculus
396214 Gallus gallus
10903177 Trichinella spiralis
100136749 Oncorhynchus mykiss
398334 Xenopus laevis
100220245 Taeniopygia guttata
64264 Danio rerio
100714212 Cavia porcellus
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