Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2) Kits ELISA

PIM2 encodes a protooncogene that acts as a serine/threonine protein kinase. De plus, nous expédions Proto-Oncogene Pim-2 (Serine Threonine Kinase) Anticorps (130) et Proto-Oncogene Pim-2 (Serine Threonine Kinase) Protéines (18) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PIM2 11040 Q9P1W9
Anti-Rat PIM2 PIM2 317366  
PIM2 18715 Q62070
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.257 ng/mL 0.62 ng/mL - 40 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
  96 Tests Connectez-vous pour afficher 2 to 3 Days

Plus Kits ELISA pour Proto-Oncogene Pim-2 (Serine Threonine Kinase) partenaires d'interaction

Zebrafish Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2) interaction partners

  1. Inhibition of the Pim1 (Montrer PIM1 Kits ELISA) oncogene (Montrer RAB1A Kits ELISA) results in diminished visual function.

Human Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2) interaction partners

  1. Inhibition of PIM2 attenuated asthma symptoms and increased expression levels of interleukin (IL)10 (Montrer IL10 Kits ELISA) and forkhead box protein 3 (Montrer HSPB3 Kits ELISA) (FOXP3 (Montrer FOXP3 Kits ELISA)) in bronchoalveolar lavage fluid.

  2. data suggest that PIM1 (Montrer PIM1 Kits ELISA)/2 kinase overexpression is a common feature of male reproductive organs tumors, which provoke tissue alterations and a large inflammatory response that may act synergistically during the process of tumorigenesis.

  3. show that PIM1 (Montrer PIM1 Kits ELISA) contributes to melanoma cell proliferation and tumor growth in vivo; however, the presence of PIM2 and PIM3 (Montrer PIM3 Kits ELISA) could also influence the outcome.

  4. the elevated expression of PIM2 in blastic cells is associated with poor prognosis of AML (Montrer RUNX1 Kits ELISA) patients and their resistance to induction therapy.

  5. Our data provide evidence for a novel role for Pim2 in the regulation of the DNA damage response (DDR (Montrer DDR1 Kits ELISA)). Knockdown of Pim2 upregulates several downstream DDR (Montrer DDR1 Kits ELISA) markers, mimicking the effects of doxorubicin (Dox) treatment of MM cells, and suggesting a role for the kinase as a negative regulator of this pathway.

  6. These results demonstrate the involvement of PIM (Montrer PIM1 Kits ELISA) kinases in LIF (Montrer LIF Kits ELISA)-induced regulation in different trophoblastic cell lines which may indicate similar functions in primary cells.

  7. PIM (Montrer PIM1 Kits ELISA) kinases in classical Hodgkin lymphoma exhibit pleiotropic effects, orchestrating tumor immune escape and supporting Reed-Sternberg cell survival.

  8. High PIM2 expression is associated with osteosarcoma.

  9. We show that Pim2 inhibitors and proteasome inhibitors, such as bortezomib, have additive effects to inhibit the growth of myeloma cells, suggesting that Pim2 could be an interesting target for the treatment of multiple myeloma.

  10. PIM2 gene knockdown enhances the anti-proliferative effect of AZD1208 in non-Hodgkin lymphoma cell line.

Mouse (Murine) Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2) interaction partners

  1. studies define a pathway for limiting the regulation of Foxp3 (Montrer FOXP3 Kits ELISA) function because the Pim-2 kinase represents a potential therapeutic target for modulating the Treg cell suppressive activities in controlling immune responses

  2. Pim2 facilitated allograft rejection primarily by modulating the apoptosis of effector T cells and the function of regulatory T cells.

  3. Loss of PIM2 is associated with abnormal hematopoietic phenotypes.

  4. signals from IL-7 (Montrer IL7 Kits ELISA) and RAG DSBs activate distinct Pim (Montrer PIM1 Kits ELISA) kinase family members that have context-dependent activities in regulating pre-B cell proliferation and survival.

  5. Targeting cap-dependent translation blocks converging survival signals by AKT (Montrer AKT1 Kits ELISA) and PIM 1 (Montrer PIM1 Kits ELISA), 2 kinases in lymphoma

  6. PIM2 controls the expression of the pro-inflammatory cytokine IL-6 (Montrer IL6 Kits ELISA).

  7. results support the hypothesis that Pim2, which is also a known target of Flt3 (Montrer FLT3 Kits ELISA)-ITD (another gene that cooperates with PML (Montrer PML Kits ELISA)-RARalpha (Montrer RARA Kits ELISA)), cooperates with PRalpha to induce acute promyelocytic leukemia (Montrer PML Kits ELISA)-like disease

  8. Pim-2 is a direct link between growth factor-induced transcription and a novel, kinase-dependent pathway that promotes cell-autonomous survival

  9. pim-2 functions similarly to pim-1 (Montrer PIM1 Kits ELISA) as a pro-survival kinase; BAD is a legitimate PIM-2 substrate

  10. Pim-2 and Akt-1 (Montrer AKT1 Kits ELISA) are critical components of overlapping but independent pathways, either of which is sufficient to promote the growth and survival of nontransformed hematopoietic cells

Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2) profil antigène

Antigen Summary

This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.

Gene names and symbols associated with PIM2

  • Pim-2 proto-oncogene, serine/threonine kinase (pim2) anticorps
  • Pim-2 proto-oncogene, serine/threonine kinase (PIM2) anticorps
  • Pim-2 proto-oncogene, serine/threonine kinase (Pim2) anticorps
  • proviral integration site 2 (Pim2) anticorps
  • cb1068 anticorps
  • DXCch3 anticorps
  • fj47b05 anticorps
  • Pim-2 anticorps
  • pim2 anticorps
  • wu:fj47b05 anticorps

Protein level used designations for PIM2

kinase pim-1 , proviral integration site 2 , serine/threonine-protein kinase Pim-1 , serine/threonine-protein kinase pim-2 , pim-2h , proto-oncogene Pim-2 (serine threonine kinase) , serine/threonine protein kinase pim-2 , serine/threonine kinase

58054 Danio rerio
11040 Homo sapiens
442959 Canis lupus familiaris
508424 Bos taurus
317366 Rattus norvegicus
473600 Pan troglodytes
18715 Mus musculus
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