anti-Pyridoxamine 5'-Phosphate Oxidase (PNPO) Anticorps

The enzyme encoded by PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. De plus, nous expédions PNPO Protéines (15) et PNPO Kits (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PNPO 55163 Q9NVS9
PNPO 64533 O88794
PNPO 103711 Q91XF0
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Top anti-PNPO Anticorps sur anticorps-enligne.fr

Showing 10 out of 77 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-PNPO Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Muscle 100 μL 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué FACS, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Souris Inconjugué EIA, WB 0.1 mL 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of PNPO Antibody (C-term) in 293 cell line lysates (35ug/lane). PNPO (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Souris Inconjugué ELISA, IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-PNPO antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μL 11 to 14 Days
$484.00
Détails
Cheval Lapin Inconjugué IHC, IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 to 14 Days
$727.83
Détails
Humain Souris Inconjugué FACS, IHC, WB Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-PNPO mouse monoclonal antibody. (ABIN2455004) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PNPO (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PNPO. 0.1 mL 2 to 3 Days
$462.00
Détails
Humain Souris Inconjugué FACS, IF, WB HEK293T cells transfected with either RC200133 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PNPO antibody (ABIN2454781), and then analyzed by flow cytometry. Anti-PNPO mouse monoclonal antibody (ABIN2454781) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNPO (RC200133). 0.1 mL 2 to 3 Days
$462.00
Détails
Humain Souris Inconjugué IHC, WB Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-PNPO mouse monoclonal antibody. (ABIN2454900) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PNPO (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PNPO. 0.1 mL 2 to 3 Days
$462.00
Détails

anti-PNPO Anticorps mieux référencés

  1. Human Polyclonal PNPO Primary Antibody pour ELISA, WB - ABIN565829 : Khayat, Korman, Frankel, Weintraub, Hershckowitz, Sheffer, Ben Elisha, Wevers, Falik-Zaccai: PNPO deficiency: an under diagnosed inborn error of pyridoxine metabolism. dans Molecular genetics and metabolism 2008 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal PNPO Primary Antibody pour WB - ABIN2787718 : Song, Ueno, Numata, Iga, Shibuya-Tayoshi, Nakataki, Tayoshi, Yamauchi, Sumitani, Tomotake, Tada, Tanahashi, Itakura, Ohmori: Association between PNPO and schizophrenia in the Japanese population. dans Schizophrenia research 2007 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre PNPO partenaires d’interaction

Human Pyridoxamine 5'-Phosphate Oxidase (PNPO) interaction partners

  1. TGF-beta1-mediated PNPO expression was at least in part through the upregulation of miR-143-3p in epithelial ovarian cancer.

  2. data support a pathogenic role of the c.347G>A (p.Arg116Gln) mutation in PNPO deficiency; the later onset of symptoms and the milder epilepsy phenotype of these expand the disease phenotype

  3. Exome sequencing revealed that the patient was compound heterozygous for pathogenic mutations [c.546+1G>A (IVS5+1 G>A) and c.620delG (p.G207VfsX215)] in the PNPO gene.

  4. One sequence variant, R116Q, a single nucleotide polymorphism that has been reported in the general population, was found to have an effect on PNPO activity.

  5. Challenge to the paradigm of exclusive PLP responsiveness in patients with pyridoxal 5'-phosphate oxidase deficiency and underlines the importance of consecutive testing of pyridoxine and PLP in neonates with antiepileptic drug-resistant seizures.

  6. Generalized epilepsies implicates susceptibility genes: CHRM3 at 1q43, VRK2 at 2p16.1, ZEB2 at 2q22.3, SCN1A at 2q24.3 and PNPO at 17q21.32.

  7. provide evidence that a single arginine residue of the C terminus of pyridoxal 5'-phosphate synthase is responsible for coordinating co-operativity in this elaborate protein machinery

  8. Results describe a combined computer and biochemical approach to characterize human pyridoxine 5'-phosphate oxidase (PNPO).

  9. several mutations appear to cause epilepsy

  10. We examined 8 single nucleotide polymorphisms (SNPs) in PNPO and its 5'-flanking regions in 359 schizophrenia patients and 582 control subjects.

  11. Sequencing of the PNPO gene revealed a novel homozygous nonsense mutationt in exon 3 in the neonatal and infantile seizure.

  12. PNP oxidase R229W mutation identified in patients with neonatal epileptic encephalopathy sgnificantly affect the catalytic efficiency of the enzyme.

PNPO profil antigène

Profil protéine

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Gene names and symbols associated with PNPO

  • pyridoxamine 5'-phosphate oxidase (pnpo) anticorps
  • pyridoxine 5'-phosphate oxidase (pdxH) anticorps
  • pyridoxamine 5'-phosphate oxidase (Mrub_2888) anticorps
  • pyridoxamine 5'-phosphate oxidase (Arnit_1624) anticorps
  • pyridoxamine 5'-phosphate oxidase (Ndas_4168) anticorps
  • pyridoxamine 5'-phosphate oxidase (Mesil_2817) anticorps
  • Pyridoxamine 5'-phosphate oxidase (Isop_0296) anticorps
  • Pyridoxamine 5'-phosphate oxidase (Despr_1960) anticorps
  • Pyridoxamine 5'-phosphate oxidase (Pedsa_1348) anticorps
  • pyridoxamine 5'-phosphate oxidase (Mesop_5639) anticorps
  • pyridoxamine 5'-phosphate oxidase (PNPO) anticorps
  • pyridoxamine 5'-phosphate oxidase (Pnpo) anticorps
  • pyridoxine 5'-phosphate oxidase (Pnpo) anticorps
  • AI415282 anticorps
  • ECK1634 anticorps
  • im:7138360 anticorps
  • JW1630 anticorps
  • PDXPO anticorps

Protein level used designations for PNPO

pyridoxine-5'-phosphate oxidase , pyridoxamine 5'-phosphate oxidase , Pyridoxamine 5'-phosphate oxidase , pyridoxal 5'-phosphate synthase , pyridoxamine-phosphate oxidase , pyridoxine 5'-phosphate oxidase , pyridoxine 5-phosphate oxidase

GENE ID SPECIES
402868 Danio rerio
946806 Escherichia coli str. K-12 substr. MG1655
8881004 Meiothermus ruber DSM 1279
9171784 Arcobacter nitrofigilis DSM 7299
9248042 Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111
9252339 Meiothermus silvanus DSM 9946
10154400 Isosphaera pallida ATCC 43644
10174688 Desulfobulbus propionicus DSM 2032
10230903 Pedobacter saltans DSM 12145
10829504 Mesorhizobium opportunistum WSM2075
55163 Homo sapiens
480540 Canis lupus familiaris
512573 Bos taurus
64533 Rattus norvegicus
103711 Mus musculus
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